Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis

Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription

(2017) Kenia Ubieta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages

(2017) Nicole Hannemann et al.   JOURNAL OF IMMUNOLOGY

c-Jun Is Required for Nuclear Factor-κB–Dependent, LPS-Stimulated Fos-Related Antigen-1 Transcription in Alveolar Macrophages

(2016) Rakesh K. Mishra et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Species differences of 11beta-hydroxysteroid dehydrogenase type 2 function in human and rat term placenta determined via LC-MS/MS

(2016) Kirsten Heussner et al.   PLACENTA

TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection

(2016) Ulrike Schleicher et al.   Cell Reports

Visualization of Fra-1/AP-1 activation during LPS-induced inflammatory lung injury using fluorescence optical imaging

(2015) Subbiah Rajasekaran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Fra-1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitro

(2015) SONGSHU XIAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis

(2015) Leticia Monin et al.   JOURNAL OF CLINICAL INVESTIGATION

Fra-1 is upregulated in lung cancer tissues and inhibits the apoptosis of lung cancer cells by the P53 signaling pathway

(2015) GUANGWEI ZHONG et al.   ONCOLOGY REPORTS

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

Arginase: an old enzyme with new tricks

(2015) Ruth B. Caldwell et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Fra-2/AP-1 controls adipocyte differentiation and survival by regulating PPARγ and hypoxia

(2014) J Luther et al.   CELL DEATH AND DIFFERENTIATION

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Small Molecule Inhibitors Targeting Activator Protein 1 (AP-1)

(2014) Na Ye et al.   JOURNAL OF MEDICINAL CHEMISTRY

FOS-like antigen 1 is highly expressed in human psoriasis tissues and promotes the growth of HaCaT cells in vitro

(2014) WU ZHU et al.   Molecular Medicine Reports

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis

(2013) Subbiah Rajasekaran et al.   BMC GENOMICS

IL-17A Induces Pro-Inflammatory Cytokines Production in Macrophages via MAPKinases, NF-κB and AP-1

(2013) Jian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Local Arginase 1 Activity Is Required for Cutaneous Wound Healing

(2013) Laura Campbell et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Increased circulating myeloid-derived suppressor cells correlated negatively with Th17 cells in patients with rheumatoid arthritis

(2012) Z Jiao et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Genetic Disruption of Fra-1 Decreases Susceptibility to Endotoxin-Induced Acute Lung Injury and Mortality in Mice

(2011) Michelle Vaz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase

(2011) D. R. Sharda et al.   JOURNAL OF IMMUNOLOGY

Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1

(2011) Y Takada et al.   ONCOGENE

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages

(2010) Qingshan Wang et al.   CELL RESEARCH

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Regulation of macrophage function in tumors: the multifaceted role of NF- B

(2009) T. Hagemann et al.   BLOOD

L-Arginine deprivation impairs Leishmania major-specific T-cell responses

(2009) Markus Munder et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cyclic Adenosine Monophosphate Suppresses the Transcription of Proinflammatory Cytokines via the Phosphorylated c-Fos Protein

(2009) Keiko Koga et al.   IMMUNITY

Mammalian polyamine metabolism and function

(2009) Anthony E. Pegg   IUBMB LIFE

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1

(2008) Yukihiko Aikawa et al.   NATURE BIOTECHNOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY