PIWIL1 suppresses circadian rhythms through GSK3β‐induced phosphorylation and degradation of CLOCK and BMAL1 in cancer cells

Cancer-testis gene PIWIL1 promotes cell proliferation, migration, and invasion in lung adenocarcinoma

(2017) Kaipeng Xie et al.   Cancer Medicine

Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism

(2016) Jiyeon Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Piwi-interacting RNAs and PIWI genes as novel prognostic markers for breast cancer

(2016) Preethi Krishnan et al.   Oncotarget

Overexpression of Hiwi Promotes Growth of Human Breast Cancer Cells

(2014) Da-Wei Wang et al.   Asian Pacific Journal of Cancer Prevention

Silencing HIWI suppresses the growth, invasion and migration of glioma cells

(2014) XIUYU WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hiwi downregulation, mediated by shRNA, reduces the proliferation and migration of human hepatocellular carcinoma cells

(2014) YINGJUN XIE et al.   Molecular Medicine Reports

The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

(2014) Nicole C. Gossan et al.   NUCLEIC ACIDS RESEARCH

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(2013) Christos Savvidis et al.   MOLECULAR MEDICINE

Inhibition of GSK3 by lithium, from single molecules to signaling networks

(2012) Laure Freland et al.   Frontiers in Molecular Neuroscience

PIWI Expression and Function in Cancer

(2012) Ryusuke Suzuki et al.   Frontiers in Genetics

A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation

(2011) Mary L. Spengler et al.   CELL CYCLE

A Hierarchical Phosphorylation Cascade That Regulates the Timing of PERIOD Nuclear Entry Reveals Novel Roles for Proline-Directed Kinases and GSK-3 /SGG in Circadian Clocks

(2010) H. W. Ko et al.   JOURNAL OF NEUROSCIENCE

Regulation of BMAL1 Protein Stability and Circadian Function by GSK3β-Mediated Phosphorylation

(2010) Saurabh Sahar et al.   PLoS One

THE CROSSTALK BETWEEN PHYSIOLOGY AND CIRCADIAN CLOCK PROTEINS

(2009) David Duguay et al.   CHRONOBIOLOGY INTERNATIONAL

Roles of CLOCK Phosphorylation in Suppression of E-Box-Dependent Transcription

(2009) H. Yoshitane et al.   MOLECULAR AND CELLULAR BIOLOGY