HDAC5 catalytic activity suppresses cardiomyocyte oxidative stress and NRF2 target gene expression

Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition

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Developing New Treatments for Heart Failure

(2016) Mihai Gheorghiade et al.   Circulation-Heart Failure

Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle

(2015) Douglas D. Lemon et al.   FEBS LETTERS

The Nuclear Factor Erythroid 2–Related Factor 2 Activator Oltipraz Attenuates Chronic Hypoxia–Induced Cardiopulmonary Alterations in Mice

(2013) Shunsuke Eba et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

(2013) Yang Bai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

(2013) Mercedes Lobera et al.   Nature Chemical Biology

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy

(2013) B. S. Ferguson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Oxidative Stress in the Nucleus Caused by Nox4 Mediates Oxidation of HDAC4 and Cardiac Hypertrophy

(2012) Shouji Matsushima et al.   CIRCULATION RESEARCH

Triterpenoid Dihydro-CDDO-Trifluoroethyl Amide Protects against Maladaptive Cardiac Remodeling and Dysfunction in Mice: A Critical Role of Nrf2

(2012) Yifan Xing et al.   PLoS One

Plaque Assay for Murine Norovirus

(2012) Mariam B. Gonzalez-Hernandez et al.   Jove-Journal of Visualized Experiments

Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

(2011) Douglas D. Lemon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Small-Molecule Inducer of the Antioxidant Response Element

(2010) Wooyoung Hur et al.   CHEMISTRY & BIOLOGY

Modulation of Angiotensin II–Mediated Cardiac Remodeling by the MEF2A Target Gene Xirp2

(2010) Sarah A. McCalmon et al.   CIRCULATION RESEARCH

Chemical phylogenetics of histone deacetylases

(2010) James E Bradner et al.   Nature Chemical Biology

ConsensusPathDB: toward a more complete picture of cell biology

(2010) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress

(2009) Jinqing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of redox modulation of class II histone deacetylases in mediating pathological cardiac hypertrophy

(2009) Shin-ichi Oka et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Dihydro-CDDO-Trifluoroethyl Amide (dh404), a Novel Nrf2 Activator, Suppresses Oxidative Stress in Cardiomyocytes

(2009) Tomonaga Ichikawa et al.   PLoS One

A Redox-Dependent Pathway for Regulating Class II HDACs and Cardiac Hypertrophy

(2008) Tetsuro Ago et al.   CELL

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Cardiac Plasticity

(2008) Joseph A. Hill et al.   NEW ENGLAND JOURNAL OF MEDICINE

ConsensusPathDB—a database for integrating human functional interaction networks

(2008) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH