Prostate Cancer and Bone Metastases: The Underlying Mechanisms

Dual targeting c-met and VEGFR2 in osteoblasts suppresses growth and osteolysis of prostate cancer bone metastasis

(2018) Changki Lee et al.   CANCER LETTERS

Exosomal miR-141-3p regulates osteoblast activity to promote the osteoblastic metastasis of prostate cancer

(2017) Yun Ye et al.   Oncotarget

Cabozantinib (XL184) in metastatic castration-resistant prostate cancer (mCRPC): Results from a phase II randomized discontinuation trial.

(2017) M. Hussain et al.   JOURNAL OF CLINICAL ONCOLOGY

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells

(2017) Carmen Streicher et al.   Scientific Reports

Estrogen and estrogen receptor alpha promotes malignancy and osteoblastic tumorigenesis in prostate cancer

(2015) Sweta Mishra et al.   Oncotarget

The IGR-CaP1 Xenograft Model Recapitulates Mixed Osteolytic/Blastic Bone Lesions Observed in Metastatic Prostate Cancer

(2015) Nader Al Nakouzi et al.   NEOPLASIA

Secretome Analysis of an Osteogenic Prostate Tumor Identifies Complex Signaling Networks Mediating Cross-talk of Cancer and Stromal Cells Within the Tumor Microenvironment

(2014) Yu-Chen Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

Prostate cancer cells induce osteoblastic differentiation via semaphorin 3A

(2014) Fuzhou Liu et al.   PROSTATE

Molecular Signaling Pathways Mediating Osteoclastogenesis Induced by Prostate Cancer Cells

(2013) Shahrzad Rafiei et al.   BMC CANCER

The clinical utility of bone marker measurements in osteoporosis

(2013) Gillian Wheater et al.   Journal of Translational Medicine

Estrogen and the skeleton

(2012) Sundeep Khosla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dasatinib combined with docetaxel for castration-resistant prostate cancer

(2011) John C. Araujo et al.   CANCER

Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial

(2011) Matthew R Smith et al.   LANCET

Bone metastasis: mechanisms and therapeutic opportunities

(2011) Larry J. Suva et al.   Nature Reviews Endocrinology

Blockade of transforming growth factor-beta (TGFβ) signaling inhibits osteoblastic tumorigenesis by a novel human prostate cancer cell line

(2011) Sweta Mishra et al.   PROSTATE

Ectopic Production of Parathyroid Hormone in a Patient with Sporadic Medullary Thyroid Cancer

(2010) Masashi DEMURA et al.   ENDOCRINE JOURNAL

Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling

(2009) Åse Bratland et al.   CLINICAL & EXPERIMENTAL METASTASIS

Denosumab in Men Receiving Androgen-Deprivation Therapy for Prostate Cancer

(2009) Matthew R. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

The expression of osteoclastogenesis-associated factors and osteoblast response to osteolytic prostate cancer cells

(2009) Colm Morrissey et al.   PROSTATE

The endothelin axis in cancer: the promise and the challenges of molecularly targeted therapyThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.

(2008) Anna Bagnato et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Prostate Cancer, Serum Parathyroid Hormone, and the Progression of Skeletal Metastases

(2008) G. G. Schwartz   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Prostate Cancer Induces Bone Metastasis through Wnt-Induced Bone Morphogenetic Protein-Dependent and Independent Mechanisms

(2008) J. Dai et al.   CANCER RESEARCH

Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone

(2008) Yi Lu et al.   CLINICAL & EXPERIMENTAL METASTASIS

Soluble ErbB3 Levels in Bone Marrow and Plasma of Men with Prostate Cancer

(2008) S.-H. Lin et al.   CLINICAL CANCER RESEARCH

Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions

(2008) Jinhui Liao et al.   INTERNATIONAL JOURNAL OF CANCER

Androgen receptor–negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms

(2008) Zhi Gang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling

(2007) William A. Ricke et al.   FASEB JOURNAL

The role of estrogens and estrogen receptors in normal prostate growth and disease

(2007) Gail S. Prins et al.   STEROIDS