Article
Plant Sciences
Begona Miras-Moreno, Biancamaria Senizza, Luca Regni, Ciro Tolisano, Primo Proietti, Marco Trevisan, Luigi Lucini, Youssef Rouphael, Daniele Del Buono
Summary: This study found that a plant extract of an aquatic species, Lemna minor L. (LE), can improve the resistance of maize to copper toxicity. LE can reverse the effects of copper on maize photosynthetic activity, evapotranspiration, stomatal conductance, sub-stomatal CO2 concentration, and biomass. Furthermore, LE can reduce the content of hydrogen peroxide and malondialdehyde and increase the activity of antioxidant enzymes in maize. Untargeted metabolomic profiling revealed that LE can activate maize secondary metabolism and modulate plant stress-related hormones and non-enzymatic antioxidants. These findings have important implications for using LE as a biostimulant to enhance the resistance of maize to metal trace elements.
Article
Biology
Jolanta Nawrocka-Rutkowska, Iwona Szydlowska, Katarzyna Jakubowska, Maria Olszewska, Dariusz Chlubek, Aleksandra Ryl, Malgorzata Szczuko, Andrzej Starczewski
Summary: Polycystic ovary syndrome (PCOS) is a common endocrinopathy in reproductive-age females that is associated with metabolic disorders. This study identified abnormal oxidative stress (OS) parameters in patients with PCOS and found that insulin resistance (IR) may be the main risk factor for exposure to OS in these patients. Additionally, glutathione peroxidase (GPx) plays a crucial role in the development of PCOS.
Article
Biology
Tatyana Sakharova, Almas Mukhametov, Dmitry Bokov
Summary: The present study examines the culture of propionic acid bacteria (PAB) and the effects of iron ions on their enzymatic activity and growth rate. Results show that increased iron concentration leads to increased enzyme activity, but excessive iron content inhibits bacterial growth and metabolism. Optimal iron ion doses for active PAB growth were determined. The study also highlights the high adhesion capabilities of certain PAB strains.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Environmental Sciences
Azra Yasmin, Samina Ambreen, Sumera Shabir
Summary: Bacterial strain Pseudomonas kilonensis MB490 isolated from agricultural fields in Mianwali showed promising potential in degrading the organophosphate insecticide dimethoate. The strain exhibited efficient degradation of dimethoate under varying pH and temperature conditions, with optimal degradation observed under shaking conditions. Overall, the study demonstrates the effectiveness of strain MB490 in degrading dimethoate and its metabolites, showcasing its potential for bioremediation applications.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES
(2022)
Article
Chemistry, Inorganic & Nuclear
Janetsi Y. Caro-Ramirez, Juliana E. Parente, Gisela M. Gaddi, Nancy Martini, Carlos A. Franca, Nora M. Urquiza, Luis Lezama, Oscar E. Piro, Gustavo A. Echeverria, Patricia A. M. Williams, Evelina G. Ferrer
Summary: In this study, a binuclear copper(II) complex with a unique crystal structure was synthesized through a redox process. The complex showed excellent catalytic performance in various reactions. The molecular structure and electronic properties of the complex were determined through comprehensive experimental characterization and computational analysis. Additionally, the catalytic properties and structural features of the complex were compared with other copper(II) metal complexes, and its interaction with albumin was also investigated.
Article
Biochemistry & Molecular Biology
Gita Kholghi, Vahide Alipour, Maede Rezaie, Mohammad-Reza Zarrindast, Salar Vaseghi
Summary: Sleep deprivation has negative effects on cognitive functions, but some studies suggest it may improve cognitive functions. This study investigated the effects of 4-hour and 24-hour sleep deprivation, as well as mild short-term and moderate long-term treadmill exercise, on spatial memory performance and oxidative and antioxidant markers in rats. The results showed that 24-hour sleep deprivation and long-term moderate treadmill exercise had negative effects on memory and oxidative status. However, both treadmill exercise protocols reversed the negative effects of sleep deprivation on memory and oxidative stress.
NEUROCHEMICAL RESEARCH
(2023)
Review
Forestry
Kseniya M. Nikerova, Natalia A. Galibina, Yulia L. Moshchenskaya, Tatiana V. Tarelkina, Marina N. Borodina, Irina N. Sofronova, Ludmila I. Semenova, Diana S. Ivanova, Ludmila L. Novitskaya
Summary: AOS enzymes can serve as biochemical indicators of abnormal xylogenesis in Karelian birch. The increase in enzymatic activity is correlated with the intensity of wood figure, reflecting different biochemical strategies in various xylogenesis scenarios. Results demonstrate that the formation of figured wood is closely linked to secondary metabolism processes, with AOS enzymes acting as markers of figured wood formation during active cambial growth.
TREES-STRUCTURE AND FUNCTION
(2022)
Article
Microbiology
Daniel Gonzalez-Reguero, Marina Robas-Mora, Agustin Probanza, Pedro A. Jimenez
Summary: This study evaluates the phytoprotective capacity of bacterial strains and their consortia in Lupinus albus var. orden Dorado. The results show that the inoculation of strains B1 and B2, as well as their corresponding consortium, significantly improves plant growth and resistance against Hg contamination.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Nutrition & Dietetics
Maria Dolores Ordonez-Diaz, Mercedes Gil-Campos, Katherine Flores-Rojas, Maria Carmen Munoz-Villanueva, Maria Dolores Mesa, Maria Jose de la Torre-aguilar, Angel Gil, Juan Luis Perez-Navero
Summary: This study demonstrates that prepubertal children with a history of prematurity but without FGR have impaired antioxidant status, particularly in those with EUGR. This could potentially increase the risk of adverse metabolic outcomes later in life.
FRONTIERS IN NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Marta Janczak-Pieniazek, Jan Cichonski, Patrycja Michalik, Grzegorz Chrzanowski
Summary: Heavy metal stress inhibits cellular processes and decreases plant productivity. Phenolic compounds play significant roles in plants' response to stress. Increasing biosynthesis of phenolic compounds protects plants from oxidative stress caused by heavy metal stress.
Article
Multidisciplinary Sciences
Nurkhasanah Mahfudh, Nanik Sulistyani, Asiilah Fatihatul Khoirot, Tsanawiyah Indah Safira, Fezah Othman, Zainul Amiruddin Zakaria
Summary: This study investigated the effect of the ethanol extract of purple sweet potato leaves on the endogenous antioxidant activity in hyperlipidemic rats. The results showed that the extract significantly increased the activities of SOD, CAT, and GSH-Px, and lowered the MDA level.
Article
Plant Sciences
E. H. M. Cisse, D-D Li, J. Zhang, L-Y Guo, L-F Miao, F. Yang
Summary: This study investigated the effect of exogenous glycine betaine on Dalbergia odorifera under cold and drought stresses. The results showed that glycine betaine had significant beneficial impacts on the phenotypic traits, antioxidant machinery, photosynthetic pigments, and water status of D. odorifera seedlings.
BIOLOGIA PLANTARUM
(2022)
Article
Biochemistry & Molecular Biology
Stephanie Coakley, Gary Cahill, Anne-Marie Enright, Brian O'Rourke, Carloalberto Petti
Summary: The study investigates the impact of cadmium on Impatiens glandulifera, focusing on its stress response and enzymatic activities. Results show that exposure to cadmium induces oxidative stress and enhances the activity of antioxidant enzymes. Despite an increase in detoxifying enzyme activity, plants did not show significant physiological stress in the presence of cadmium.
BIOCHEMISTRY AND BIOPHYSICS REPORTS
(2021)
Article
Environmental Sciences
Majid Jasim Fahad, Asaad Kadhim Abdullah
Summary: Sulphur oxide is a serious issue in air pollution, and this study found that sulphur dioxide stress increased antioxidant enzyme and non-enzymatic antioxidant activities in tomato plants. Spraying trehalose helped mitigate the negative effects of sulphur dioxide.
ASIAN JOURNAL OF WATER ENVIRONMENT AND POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Magdalena Wojciak, Aleksandra Ziemlewska, Martyna Zagorska-Dziok, Zofia Niziol-Lukaszewska, Dariusz Szczepanek, Tomasz Oniszczuk, Ireneusz Sowa
Summary: This study aimed to evaluate the antioxidant, anti-inflammatory, and protective effects of Sambucus nigra fruit extract and its ferment obtained through fermentation with kombucha tea fungus. The chemical composition of fermented and non-fermented extracts was compared using HPLC/ESI-MS chromatographic method. The antioxidant activity of the samples was assessed using DPPH and ABTS assays. The results showed that the extract and the ferment possess antioxidant properties and promote cell proliferation in both fibroblast and keratinocyte skin cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Jaromir Jarecki, Izabela Polkowska, Waldemar Kazimierczak, Magdalena Wojciak, Ireneusz Sowa, Slawomir Dresler, Tomasz Blicharski
Summary: The aim of this study was to assess the impact of physical activity on the musculoskeletal system in an animal model of early degenerative knee joint lesions. The results showed that compared to inactive rats, active rats had decreased bone density, reduced weight of fat and muscle tissues, indicating the impact of physical activity on bone mineralization.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Aleksandra Ziemlewska, Martyna Zagorska-Dziok, Zofia Niziol-Lukaszewska, Patrycja Kielar, Mateusz Molon, Dariusz Szczepanek, Ireneusz Sowa, Magdalena Wojciak
Summary: This study compared the antioxidant properties of extracts and ferments from R. nigrum L., A. melanocarpa Michx., and V. myrtillus L. The ferments showed a greater variety of biologically active compounds, strong antioxidant properties, and the ability to reduce oxidative stress in human and yeast cells. The results suggest that the tested ferments can be considered as valuable raw materials for protecting cells against oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Slawomir Dresler, Maciej Strzemski, Izabela Baczewska, Mateusz Koselski, Mohammad Bagher Hassanpouraghdam, Dariusz Szczepanek, Ireneusz Sowa, Magdalena Wojciak, Agnieszka Hanaka
Summary: Soybeans are a valuable source of biologically active compounds such as isoflavones, allantoin, and alpha-hydroxy acids. This study optimized three solvent systems to increase the efficiency of extracting these compounds from soybean leaves. A mixture design with three solvents was used to create an experimental plan, and polynomial regression models were developed based on the results. The optimal solvent mixture composition provided high extraction efficiency and antioxidant properties.
Article
Agricultural Engineering
Slawomir Dresler, Aleksandra Ziemlewska, Zofia Niziol-Lukaszewska, Martyna Zagorska-Dziok, Tomasz Bujak, Kamil Skic, Marcin Feldo, Agnieszka Hanaka, Magdalena Wojciak, Ireneusz Sowa, Maciej Strzemski
Summary: This study aimed to optimize a three-solvent system to maximize the extraction efficiency of active compounds in comfrey. The optimized solvent composition showed good extraction efficiency and high antioxidant properties, but did not show correlation with metalloproteinase activity and cell viability inhibition. Further in vivo studies are needed to evaluate the practical application of the extracts in the cosmetic industry.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Marcin Feldo, Magdalena Wojciak, Slawomir Dresler, Pawel Sowa, Bartosz J. Plachno, Dariusz Samborski, Ireneusz Sowa
Summary: Chronic venous disease (CVD) affects up to 30% of the global population and is characterized by disturbances in the microcirculation of veins. Diosmin, a phlebotropic drug, has been used in the treatment of CVD, but its molecular mechanism of action is not fully understood. In this study, patients were administered diosmin and biochemical assays were used to evaluate its effects on oxygen management, angiogenesis, and inflammation. The findings suggest that diosmin may regulate angiogenesis, inflammation, and hypoxia-inducible factor pathway in CVD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Agnieszka Hanaka, Slawomir Dresler, Wieslaw Mulenko, Magdalena Wojciak, Ireneusz Sowa, Magdalena Sawic, Katarzyna Stanislawek, Maciej Strzemski
Summary: This study investigated the impact of the herbivore Cameraria ohridella and the pathogen Erysiphe flexuosa on secondary metabolite accumulation in chestnut leaves. The results showed that the accumulation of metabolites depended on the degree of pest infection, indicating the development of a metabolic response mechanism in chestnut trees to biological stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Anna Danielewicz, Magdalena Wojciak, Ireneusz Sowa, Monika Kusz, Joanna Wessely-Szponder, Slawomir Dresler, Michal Latalski
Summary: This study investigated the concentrations of bone remodeling-related agents in adolescent idiopathic scoliosis (AIS) patients, and found that the levels of vitamin D, N-terminal propeptide of type I procollagen, and fibroblast growth factor-23 were altered in these patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Ireneusz Sowa, Jaroslaw Moldoch, Roman Paduch, Maciej Strzemski, Jacek Szkutnik, Katarzyna Tyszczuk-Rotko, Slawomir Dresler, Dariusz Szczepanek, Magdalena Wojciak
Summary: This study investigated the polyphenolic composition of Carlina acaulis and demonstrated its anti-cancer potential. The plant was found to be rich in chlorogenic acids and flavonoids. Further fractionation revealed that subfractions containing fatty acids had significant inhibitory effects on cancer cells. The research highlighted the promising attributes of C. acaulis and called for further exploration of its biological activity.
Article
Chemistry, Physical
Jedrzej Kozak, Katarzyna Tyszczuk-Rotko, Aleksy Keller, Magdalena Wojciak, Ireneusz Sowa
Summary: The purpose of this study was to develop a simple, fast, and sensitive method for determining the polyphenolic antioxidant curcumin. By electrochemically activating a screen-printed boron-doped diamond electrode, the analytical signal of curcumin was significantly amplified. Under optimized conditions, the method achieved a very low detection limit and yielded consistent results compared to other commonly used methods.
Review
Medicine, General & Internal
Jaromir Jarecki, Marcin Krzysztof Wasko, Wojciech Widuchowski, Agnieszka Tomczyk-Warunek, Magdalena Wojciak, Ireneusz Sowa, Tomasz Blicharski
Summary: This review provides an overview of the commonly used clinical methods for treating articular cartilage defects, with a specific emphasis on recent clinical trials. Currently, no single method fully satisfies the requirements for effective cartilage healing while remaining easily applicable during surgical procedures. However, there are several available options and the choice of treatment should take into consideration factors such as the location and size of the cartilage lesion, patient preferences, and whether it is chondral or osteochondral in nature. Promising future directions include tissue engineering, stem cell therapies, and the development of pre-formed scaffolds from hyaline cartilage, offering hope for improved outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)