Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/ijms20081853
Keywords
glioblastoma (GBM); SUMOylation; SUMO1-3; post-translational modifications (PTMs)
Funding
- University of Alabama at Birmingham Medical Scientist Training Program (MSTP)
- Rally Foundation for Childhood Cancer Research
- Hyundai Hope on Wheels
- Department of Defense [W81XWH-15-1-0108]
Ask authors/readers for more resources
Protein SUMOylation is a dynamic post-translational modification which is involved in a diverse set of physiologic processes throughout the cell. Of note, SUMOylation also plays a role in the pathobiology of a myriad of cancers, one of which is glioblastoma (GBM). Accordingly, herein, we review core aspects of SUMOylation as it relates to GBM and in so doing highlight putative methods/modalities capable of therapeutically engaging the pathway for treatment of this deadly neoplasm.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
