Article
Pharmacology & Pharmacy
Valerie Berger, Ludwig Gabriel, Elena Lilliu, Benjamin Hackl, Jessica Marksteiner, Karlheinz Hilber, Xaver Koenig, Pavel Uhrin, Hannes Todt
Summary: Alterations in cardiac impulse conduction can have both positive and negative effects. The assessment of ventricular conduction properties is crucial in both clinical and experimental settings. The duration and amplitude of the QRS complex are important factors to consider in evaluating ventricular conduction time in murine ECG. This study found that QRS duration and QRS amplitude were inversely related in mice, and both parameters should be considered in the analysis of ventricular conduction time.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Adam Budai, Ferenc Imre Suhai, Kristof Csorba, Zsofia Dohy, Liliana Szabo, Bela Merkely, Hajnalka Vago
Summary: A machine learning-based model was developed to automatically detect left ventricular hypertrophy in cardiac magnetic resonance images. The model achieved high accuracy and recall by introducing a standardization method. This algorithm has the potential to improve the diagnostic accuracy of left ventricular hypertrophy and has important applications in cardiac magnetic resonance.
APPLIED SCIENCES-BASEL
(2022)
Article
Cardiac & Cardiovascular Systems
Hans Henrik Odland, Torbjorn Holm, Richard Cornelussen, Erik Kongsgard
Summary: This study aimed to optimize cardiac resynchronization therapy (CRT) by exploring the acute effects of different electrical wave-front fusion strategies. The results showed that fusion pacing and multipoint pacing can shorten time-to-peak dP/dt (Td) and QRS duration (QRSd), which can improve the benefits of CRT.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Elena Galli, Virginie Le Rolle, Otto A. Smiseth, Jurgen Duchenne, John M. Aalen, Camilla K. Larsen, Elif A. Sade, Arnaud Hubert, Smitha Anilkumar, Martin Penicka, Cecilia Linde, Christophe Leclercq, Alfredo Hernandez, Jens-Uwe Voigt, Erwan Donal
Summary: This study evaluated the impact of clinical, electrocardiographic, and echocardiographic data on left ventricular remodeling and prognosis of CRT candidates. Machine learning techniques identified features predictive of CRT response and prognosis, highlighting the importance of evaluating right ventricular size and function in risk stratification of CRT candidates.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Article
Multidisciplinary Sciences
Fabiola De Marco, Filomena Ferrucci, Michele Risi, Genoveffa Tortora
Summary: Detection of Premature Ventricular Contractions (PVC) is crucial in cardiology. This study introduces a machine learning approach to identify PVCs without feature extraction and cross-validation techniques. The results show excellent performance and promising results for PVC diagnosis.
Article
Cardiac & Cardiovascular Systems
Stacey J. Howell, Tim Stivland, Kenneth Stein, Kenneth A. Ellenbogen, Larisa G. Tereshchenko
Summary: This study developed a prediction model using machine learning to identify suitable candidates for CRT, facilitating early multidisciplinary care for heart failure patients.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sam Straw, Melanie McGinlay, John Gierula, Judith E. Lowry, Maria F. Paton, Charlotte Cole, Michael Drozd, Aaron O. Koshy, Wilfried Mullens, Richard M. Cubbon, Mark T. Kearney, Klaus K. Witte
Summary: This study found that patients with wide QRS had less left ventricular reverse remodelling compared to those with narrow QRS in the absence of CRT, and patients with narrow QRS were more likely to achieve at least a 10% improvement in LVEF.
JOURNAL OF CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Mitsuhiro Fukata, Hiro Yamasaki, Eikou Sai, Kojiro Ogawa, Kenji Kuroki, Miyako Igarashi, Yukio Sekiguchi, Keizo Kimura, Yoshihiro Seo, Keita Odashiro, Koich Akashi, Akihiko Nogami, Kazutaka Aonuma
Summary: The study showed that in heart failure patients with a moderately wide QRS (120-149 ms), the use of aCRT algorithm in CRT has a significant therapeutic effect on electrical and mechanical parameters, especially in terms of the proportion of LV volume responders compared to conventional BiV-CRT.
JOURNAL OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Mohammed Ali Ghossein, Francesco Zanon, Floor Salden, Antonius van Stipdonk, Lina Marcantoni, Elien Engels, Justin Luermans, Sjoerd Westra, Frits Prinzen, Kevin Vernooy
Summary: The reduction in QRS area is associated with hemodynamic improvement by pacing different LV sites in CRT, and can guide LV lead placement. Lateral LV pacing resulted in a larger % increment LVdP/dt(max) than anterior or posterior pacing, suggesting QRS area may be useful in guiding LV lead placement.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biology
Angela W. C. Lee, Orod Razeghi, Jose Alonso Solis-Lemus, Marina Strocchi, Baldeep Sidhu, Justin Gould, Jonathan M. Behar, Mark Elliott, Vishal Mehta, Gernot Plank, Christopher A. Rinaldi, Steven A. Niederer
Summary: CRT in dyssynchronous heart failure patients is ineffective in 20-30% of cases. Non-invasive electrical and mechanical indices can predict optimal epicardial lead location, potentially reducing time, costs and risks to patients.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Yixiu Liang, Ruifeng Ding, Jingfeng Wang, Xue Gong, Ziqing Yu, Lei Pan, Jingjuan Huang, Ruogu Li, Yangang Su, Sibo Zhu, Junbo Ge
Summary: The study demonstrates that predictive models developed using machine learning can effectively evaluate the response of cardiac resynchronization therapy in patients, assisting in the early selection of suitable candidates and reducing non-response rates.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Environmental Sciences
Tao Han, Gerardo Arturo Sanchez-Azofeifa
Summary: Lianas are increasingly dominating tropical forests due to climate change. Remote sensing techniques play a key role in separating lianas from their host trees, and this separation provides valuable insights into how tropical forests respond to climate and environmental change. In this study, a new machine learning method based on Random Forest and eXtreme Gradient Boosting algorithms is proposed to separate lianas and trees using Terrestrial Laser Scanning point clouds. The method is tested on tropical dry forest trees with different levels of liana infestation, and the results show high accuracy and recall rates. This method provides a flexible approach to extract lianas from 3D point clouds and facilitates new studies on the impact of lianas on tree and forest structures.
Article
Cardiac & Cardiovascular Systems
Jason Coult, Betty Y. Yang, Heemun Kwok, J. Nathan Kutz, Patrick M. Boyle, Jennifer Blackwood, Thomas D. Rea, Peter J. Kudenchuk
Summary: This study developed an ECG-based algorithm that can predict patients with refractory ventricular fibrillation (VF). The algorithm has shown high predictive accuracy, which can help rescuers take targeted interventions in advance and improve the resuscitation outcome.
Article
Emergency Medicine
Jia-Yu Chen, Chien-Hua Huang, Wen-Jone Chen, Wei-Ting Chen, Hooi-Nee Ong, Wei-Tien Chang, Min-Shan Tsai
Summary: This study found that QRS durations at ROSC and after rewarming were associated with survival rates in cardiac arrest survivors undergoing therapeutic hypothermia. The wide-wide group had the lowest survival rate, followed by the narrow-wide group and the wide-narrow group.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Health Care Sciences & Services
Patrick Leitz, Julia Koebe, Benjamin Rath, Florian Reinke, Gerrit Frommeyer, Christian Andresen, Fatih Guener, Julian Wolfes, Philipp S. Lange, Christian Ellermann, Lars Eckardt, Dirk G. Dechering
Summary: The study revealed that QRS width during biventricular pacing, NICM, and lower NYHA class are independent predictors of mortality in long-term follow-up of CRT patients.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Orthopedics
Badaruddin Sahito, Sheikh Muhammad Ebad Ali, Sofia Fatima Farooqui, Awais Abro, Javed Ahmed, Younis
Summary: This retrospective comparative study examined the effects of neoadjuvant denosumab on the functional outcomes, recurrence rate, and complications in patients who underwent arthrodesis of the shoulder after resection of grade III giant cell tumors (GCT) of the proximal humerus. The study found no significant differences between the denosumab and non-denosumab groups in terms of functional outcomes, recurrence, and complications. However, patients in the denosumab group had lower pain scores at 6 weeks postoperatively.
EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY
(2023)
Review
Chemistry, Inorganic & Nuclear
Tanzeela Anis, Syed Mujtaba ul Hassan, Ahmat Khurshid, M. Fakhar-e-Alam, Faisal Shahzad, A. Ali, Jamil Ahmad, Nazia Hossain
Summary: This review provides a comprehensive overview of hollow, multifunctional structures for biomedical applications, with a focus on the use of nanotechnology and its unique prospects in personalized treatment, multimodal imaging, multimodal therapy, and targeted drug delivery. The performance of different materials and synthesis strategies are discussed, and the development of more sophisticated systems in the future is anticipated.
JOURNAL OF CLUSTER SCIENCE
(2023)
Article
Biodiversity Conservation
Jamil Ahmed, Li Ping Wong, Najeebullah Channa, Waqas Ahmed, Yan Piaw Chua, Muhammad Zakir Shaikh
Summary: This study investigated arsenic exposure in school environments in Pakistan and assessed its potential health risks to children. The results showed that many schools had drinking water exceeding safety limits, with arsenic risks exceeding permissible levels. Arsenic hotspots were mainly found in central districts. The findings are important in guiding policymakers to implement measures to ensure proper treatment of drinking water in schools near riverbanks.
HUMAN AND ECOLOGICAL RISK ASSESSMENT
(2023)
Article
Agronomy
Muhammad Abdullah, Muhammad Zulkiffal, Tabussam Tufail, Farah Naz Akbar, Muhammad Owais, Javed Ahmed, Ahsan Javed, Muhammad Ijaz Tabassum, Amna Kanwal, Muhammad Asghar, Muhammad Musa, M. A. Rehman Arif, Amir Hameed, Iftikhar Haider
Summary: This study aimed to incorporate barley flour into whole wheat flour to develop chapatti. Different samples of flour blend were made by adding barley at different rates, and their proximate analyses and quality variables were determined. The results showed that the addition of barley increased protein, ash, energy, and beta-glucan contents, while decreasing gluten, carbohydrates, and phytates. Similar trends were observed in the characteristics of chapatti. Sensory evaluation indicated that chapatti with 20% barley incorporation had good nutritional quality and acceptability.
CEREAL RESEARCH COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Swati Verma, Anupinder Singh, Sandeep Sharma, Paramjit Kaur, Sachin Kumar Godara, Parambir Singh Malhi, Jahangeer Ahmed, P. D. Babu, Mandeep Singh
Summary: Polycrystalline samples of M-type hexaferrite with varying chemical composition were successfully synthesized using solid state reaction technique. The structural, microstructural and magnetic properties of these samples were investigated. The results showed good phase purity, decreased crystallite size and increased cell volume with increasing dopant concentration. Furthermore, the hexaferrite samples exhibited excellent magnetic properties, making them suitable for various applications.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Biochemistry & Molecular Biology
Javed Ahmed, Mohsin Abbas Khan, Muhammad Ehsan Khalid, Irshad Ahmad, Irfan Pervaiz, Umair Khurshid, Saharish Khaliq, Kashif ur Rehman Khan, Muhammad Adeel Arshad, Ghadeer M. M. Albadrani, Ahmed E. E. Altyar, Amany A. Sayed, Mousa O. Germoush, Mohamed M. Abdel-Daim
Summary: The study synthesized and characterized different metformin derivatives with potent antidiabetic potential and minimal side-effects. Metal complexes containing Cu II and Zn II were generated using aromatic aldehydes and ketones, and characterized through various techniques. The derivatives showed significant antidiabetic activities against targeted enzymes and hold promise for future study and development.
Article
Surgery
Ceranic Miljan, Ahmed Gendia, Masood U. R. Rehman, Djukanovic Blagoje, Janic Mladen, Krdzic Igor, Stojakovic Nebojsa, Gluhovic Aleksandar, Loncar Zlatibor, Jamil Ahmed, Parvaiz Amjad
Summary: The Serbian National Training Programme for minimally invasive colorectal surgery (LapSerb) aimed to establish laparoscopic colorectal surgery across Serbia. This study reports the outcomes of laparoscopic colorectal resection performed by LapSerb certified surgeons.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Chemistry, Physical
Sanjay Kumar, Himanshi, Jyoti Prakash, Ankit Verma, Suman, Rohit Jasrotia, Abhishek Kandwal, Ritesh Verma, Sachin Kumar Godara, M. A. Majeed Khan, Saad. M. M. Alshehri, Jahangeer Ahmed
Summary: Graphene-based materials, known for their remarkable electrical, mechanical, and optical traits, have gained significant scientific interest in modern technology research. In this review paper, different synthesis methods for extracting graphene and its derivatives are discussed, along with their structural, mechanical, and optical characteristics. The application of graphene-based composites in environmental purification techniques such as filtration, adsorption, and photocatalysis is extensively reviewed, highlighting the challenges and opportunities for advanced environmental applications.
Article
Engineering, Electrical & Electronic
Sachin Kumar Godara, Sher Singh Meena, Rohit Jasrotia, Jyoti Prakash, Ankit Verma, Ranjit Singh, A. K. Srivastava, Mandeep Singh, Pradip K. Maji, Ankit Jain, Ashwani Kumar Sood, Jahangeer Ahmed, Saad M. Alshehri, Amir Mehtab, Tokeer Ahmad, Aslam Hossain, Abhishek Kandwal
Summary: In this study, M-type hexaferrites Ba0.5Ca0.5ZnxZrxFe12-2xO19 were fabricated using the sol-gel technique. The exchange of Fe3+ ions by Zn2+-Zr4+ ions was confirmed by powder X-ray diffraction patterns. The lattice parameters 'a' and 'c' increased as the doping level increased. Scanning electron microscopy images showed a slight decrease in grain size with doping. The highest saturation magnetization was observed for the x = 0.2 configuration. The coercivity decreased significantly with Zn2+-Zr4+ doping. Mossbauer spectra revealed the preferential site occupancy by dopant ions and the ionic state of Fe-ions.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Chemistry, Physical
Nisha Yadav, Shivani Shiva, Preeti Oswal, Arun Kumar, Ajai Kumar Singh, Balvinder Singh, Bidhan Pandit, Jahangeer Ahmed, Gyandshwar Kumar Rao
Summary: The paper presented the role of ligands in stabilizing colloidal silver-quantum dots (Ag-QDs) and their applications in colorimetric detection of metal ions/anions. The Ag-QDs were also used for reducing nitroaromatics and showed selective colorimetric sensing of Hg(II)/Cu(II) and I- ions. The results suggest that the ligands with donor atoms effectively stabilize the Ag-QDs and the pendant alkyl chain governs their dispersion, while the colorimetric change is attributed to ion-mediated aggregation of QDs.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Electrical & Electronic
Pargam Vashishtha, Manoj Kumar, Pukhraj Prajapat, Jahangeer Ahmed, Vidya Nand Singh, Govind Gupta
Summary: By utilizing ultraviolet-responsive gallium nitride (GaN) and infrared-activated tin selenide (SnSe), a broadband heterojunction-based optical detector was fabricated, combining the detection capabilities of GaN in the ultraviolet to visible range and SnSe in the visible to shortwave-infrared range. The detector exhibited high responsivity, low dark current, and edge contact geometry for direct access to the heterostructure interface of both materials. The device showed excellent performance across the ultraviolet-C to shortwave-infrared region, with a maximum responsivity of 128 AW-1, a noise equivalent power of 5.2 x 10-14 WHz- 1/2, and a quantum efficiency of 5 x 104% for ultraviolet illumination, and a maximum responsivity of 6.06 AW-1 and noise equivalent power of 1 x 10-12 WHz- 1 for infrared illumination. This research opens up new possibilities for wideband detection in optoelectronic applications utilizing heterostructure-based devices.
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2023)
Article
Genetics & Heredity
Cristina Skrypnyk, Aseel Ahmed Husain, Hisham Y. Hassan, Jameel Ahmed, Abdulla Darwish, Latifa Almusalam, Noureddine Ben Khalaf, Fahad Al Qashar
Summary: This study reports two Arab patients from consanguineous families diagnosed with different severities of nemaline myopathy. The clinical phenotype was linked to homozygous variants in NEB and KLHL40 genes. The study highlights the importance of detailed assessment in prenatal, neonatal, and infancy stages for accurate diagnosis and intervention of nemaline myopathy.
FRONTIERS IN GENETICS
(2023)
Article
Remote Sensing
Muhammad Awais Arshad, Jamal Ahmed, Hyochoong Bang
Summary: This study addresses the challenge of generating optimal and obstacle-free trajectories for a quadrotor in indoor environments. A complete pipeline for path planning, trajectory generation, and optimization is proposed, using a Quadratic Program (QP) with Obstacle-Free Corridor (OFC) constraints. The feasibility and performance of the approach are demonstrated through simulations, showing higher chances of convergence compared to current approaches. The proposed pipeline can plan complete paths and optimize trajectories within a few hundred milliseconds and approximately ten iterations of the optimization solver in everyday indoor settings.
Article
Green & Sustainable Science & Technology
Mahvish Aslam, Imran Shafi, Jamil Ahmed, Mirtha Silvana Garat de Marin, Emmanuel Soriano Flores, Marco Antonio Rojo Gutierrez, Imran Ashraf
Summary: This research paper examines the impact of innovative HRM practices on firm performance, using four different models to analyze small and medium enterprises in a country. The results show that most innovative HRM practices have a significant impact on labor productivity, product innovation, process innovation, and marketing innovation. These findings suggest that SMEs can benefit from implementing innovative HRM practices to achieve future growth potential.
Article
Materials Science, Multidisciplinary
Khawaja Adeel Tariq, Jamil Ahmad, Syed Ali Husnain, Muhammad Sufyan Ijaz
Summary: This research investigates the use of environment friendly materials, such as coir fibers, polypropylene fibers, and jute fibers, in concrete. By reducing the diameter of steel bars using fiber ropes, an economical reinforced concrete is produced. The study examines the compressive and flexural strength of fiber-reinforced concrete with the combination of polypropylene fiber, jute fiber ropes, and steel bars. The results show that the addition of fibers enhances the properties of concrete, increasing the flexural strength and compressive strength by 6% and 7% respectively in coir concrete with fiber ropes.
JOURNAL OF THE MECHANICAL BEHAVIOR OF MATERIALS
(2023)