Article
Chemistry, Analytical
Yuan-Jun Tong, Lu-Dan Yu, Nan Li, Qi Fu, Ke Xu, Jiajun Wei, Yu-Xin Ye, Jianqiao Xu, Fang Zhu, Janusz Pawliszyn, Gangfeng Ouyang
Summary: A new strategy for designing a multipurpose ratiometric probe is presented in this study, which can detect the presence of mercury and fluoride ions simultaneously, establishing a successful on-site water monitoring method.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
Weiliang Shen, Guoxing Hu, Hanhan Xu, Wei Sun, Yonghong Hu, Wenge Yang
Summary: Researchers designed a set of ratiometric fluorescent probes to detect SO2 derivatives, with probe NB2 showing a change from red to green fluorescence upon reaction with SO2 and exhibiting excellent optical properties.
Article
Spectroscopy
Yamin Yu, Wenlong Sheng, Caiyun Liu, Na Gao, Bin Tian, Hanchuang Zhu, Pan Jia, Zilu Li, Xue Zhang, Kun Wang, Xiwei Li, Baocun Zhu
Summary: A novel ratiometric fluorescent probe CMER was synthesized for efficient detection of mercury ions, showing fast response time and satisfactory bioimaging results.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Sumita Subedi, Lok Nath Neupane, Hyeongseok Yu, Keun-Hyeung Lee
Summary: A highly selective ratiometric fluorescent chemodosimeter was synthesized for the detection of Hg2+, which showed remarkable detection properties including high selectivity and sensitivity, large fluorescent signal changes, and well-operation in aqueous solutions. The displacement reaction between phenylboronic acid and Hg2+ ions provided a covalent adduct of mercury ion, leading to significant fluorescent signal changes when aggregated in aqueous solution. With a low detection limit of 15.2 nM, nanomolar concentrations of Hg2+ could be successfully detected, providing a ratiometric fluorescent detection method for quantifying low levels of Hg2+ in groundwater and tap water samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Review
Chemistry, Inorganic & Nuclear
Xiaojing Nan, Yuchen Huyan, Hongjuan Li, Shiguo Sun, Yongqian Xu
Summary: Transition metal ions play crucial roles in medicine, life sciences, and environmental science, but some like mercury, copper, and iron ions pose serious health and environmental risks due to biomagnification. Monitoring metal ion levels in organisms and the environment is urgent, and reaction-based fluorescent probes offer higher sensitivity and selectivity than traditional methods. Research on these probes for Hg2+, Cu2+, and Fe2+/Fe2+ detection has advanced in the past decade, with potential for interdisciplinary development in the future.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Spectroscopy
Shuangyu Liu, Xuan Zhao, Qiujuan Ma, Gege Wang, Shuqi Hou, Yijie Ma, Yujie Lian
Summary: A ratiometric fluorescent probe for H2Sn was designed and prepared based on the combination mechanism of intramolecular charge transfer (ICT) and fluorescence resonance energy transfer (FRET). The probe exhibited high selectivity and sensitivity, and was successfully used for imaging in A549 cells.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Physical
Jie Cui, Hailiang Nie, Xiaomeng Liang, Jie Bai, Xiaoling Zhang
Summary: Acidity in biological microenvironments plays a crucial role in physiology and pathology. This study developed a pyrene-derived ratiometric fluorescent probe that can sensitively and selectively monitor pH changes.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Spectroscopy
Xiao-Lei Xue, Yang Wang, Shaojin Chen, Kun-Peng Wang, Shu-Yan Niu, Qian-Shou Zong, Yi Jiang, Zhi-Qiang Hu
Summary: Monitoring intracellular pH using ratiometric fluorescent probes is important for studying biological processes including diseases. This study presents a new hemicyanine-based ratio-metric fluorescent probe with a hydroxyl group, which exhibits dual emission and can selectively respond to micro-environmental pH conditions in a range of 6.0 to 8.0. The probe can enter and accumulate in mitochondria and monitor pH microenvironmental conditions through fluorescence imaging in HepG2 cells.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Physical
Jianqiao Chang, Yu Zhang, Yike Li, Ziwei Han, Fei Tian, Chao Liu, Qiang Feng, Yuguang Wang, Jiashu Sun, Lu Zhang
Summary: This study introduces a multilayer ratiometric fluorescent nanomachine for live-cell perturbation and imaging of mRNA at single cell resolution, offering great potential for quantifying mRNA expression and modulating and imaging intratumoral mRNA.
Article
Chemistry, Multidisciplinary
Shan Wang, Bingya Wang, Lei Zhu, Ji-Ting Hou, Kang-Kang Yu
Summary: The ratiometric fluorescent probe presented in this study offers excellent photostability and chemostability for monitoring pH changes in living cells. Quantifying the down-regulation of intracellular pH during autophagy induced by various stimuli can provide valuable guidance for constructing autophagy models to study related pathological processes.
CHEMICAL COMMUNICATIONS
(2021)
Article
Spectroscopy
Jie Zhao, Jiawei Zhang, Baojun Hu, Chunyu Gao, Zan Li, Zhiwei Sun, Jinmao You
Summary: A new ratiometric fluorescent probe (APS-NA) was designed and synthesized for the detection of mercury ions in the environment and multiple biological samples. The probe shows a large Stokes shift, high selectivity, high sensitivity and naked eye visualization.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Applied
Miao Chen, Zhenhao Liang, Guanling Zeng, Yu Wang, Zihao Mai, Xiaoyu Chen, Ge Wu, Tongsheng Chen
Summary: HBQ-B is a NIR-emitting ratiometric fluorescent probe designed to detect H2O2 with specificity and a linear relationship. It can be used for imaging intracellular H2O2 in various types of cells and monitoring the dynamics of H2O2 level changes during zebrafish development.
Article
Chemistry, Analytical
Chenchen Yang, Yueyue Li, Na Wu, Yinchan Zhang, Wei Feng, Mingming Yu, Zhanxian Li
Summary: In this study, core-shell rare earth upconversion nanoparticles were synthesized and utilized for the fabrication of mercury ion colorimetric nanoprobes with rapid response and low detection limits. These nanoprobes could also be applied for Hg2+ imaging and localization in living cells and lysosomes.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Spectroscopy
Qian Zhang, Haichang Ding, Xiaohang Xu, Huaxin Wang, Gang Liu, Shouzhi Pu
Summary: In this study, a novel fluorescent probe 1 based on rhodamine and anthracene groups was designed and synthesized for the selective, sensitive, and ratiometric detection of Hg2+ using the FRET mechanism. The probe exhibited a fast response time and a visible color change, and it was successfully used for cell imaging of Hg2+ detection. The mechanism of Hg2+ detection by probe 1 was verified through various experimental techniques.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Jie Cui, Shunping Zang, Hailiang Nie, Tiaojiao Shen, Sa Su, Jing Jing, Xiaoling Zhang
Summary: Peroxynitrite (ONOO-) is a reactive oxygen species that plays a significant role in physiological and pathological processes, especially in mitochondria. A novel mitochondria-targeted ratiometric fluorescent probe Mito-NA has been developed to accurately monitor and image ONOO- fluctuations in living cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
