Alteration of splicing factors’ expression during liver disease progression: impact on hepatocellular carcinoma outcome

Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease

(2018) Yichao Zhao et al.   HEPATOLOGY

Transcriptome-Wide Analysis Reveals the Landscape of Aberrant Alternative Splicing Events in Liver Cancer

(2018) Shengli Li et al.   HEPATOLOGY

The role of RNA alternative splicing in regulating cancer metabolism

(2017) Itamar Kozlovski et al.   HUMAN GENETICS

Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription

(2017) Cecilia Patitucci et al.   JOURNAL OF CLINICAL INVESTIGATION

Alternative splicing of hepatitis B virus: A novel virus/host interaction altering liver immunity

(2017) Marion Duriez et al.   JOURNAL OF HEPATOLOGY

Collagen XVIII in tissue homeostasis and dysregulation — Lessons learned from model organisms and human patients

(2017) Ritva Heljasvaara et al.   MATRIX BIOLOGY

Dysregulation of spliceosome gene expression in advanced prostate cancer by RNA-binding protein PSF

(2017) Ken-ichi Takayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Most Alternative Isoforms Are Not Functionally Important

(2017) Michael L. Tress et al.   TRENDS IN BIOCHEMICAL SCIENCES

Alternative Splicing May Not Be the Key to Proteome Complexity

(2017) Michael L. Tress et al.   TRENDS IN BIOCHEMICAL SCIENCES

Role of insulin receptor substrates in the progression of hepatocellular carcinoma

(2017) Yoshitaka Sakurai et al.   Scientific Reports

Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans

(2016) Benjamin P. Lee et al.   AGING CELL

SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining

(2016) Lahcen Jaafar et al.   NUCLEIC ACIDS RESEARCH

Hepatocellular carcinoma

(2016) Josep M. Llovet et al.   Nature Reviews Disease Primers

Alternative splicing-regulated protein of hepatitis B virus hacks the TNF-α-stimulated signaling pathways and limits the extent of liver inflammation

(2015) Jonathan G. Pol et al.   FASEB JOURNAL

Restoration of Wnt/β-catenin signaling attenuates alcoholic liver disease progression in a rat model

(2015) Chiung-Kuei Huang et al.   JOURNAL OF HEPATOLOGY

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation

(2015) Amruta Bhate et al.   Nature Communications

Aberrant Liver Insulin Receptor Isoform A Expression Normalises with Remission of Type 2 Diabetes after Gastric Bypass Surgery

(2015) Vinko Besic et al.   PLoS One

Differential Roles of Insulin-like Growth Factor Receptor- and Insulin Receptor-mediated Signaling in the Phenotypes of Hepatocellular Carcinoma Cells

(2015) Ya-Wen Chen et al.   NEOPLASIA

Deletion of serine/arginine-rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice

(2014) Supriya Sen et al.   HEPATOLOGY

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

(2014) M. Aikio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative splicing of mutually exclusive exons—A review

(2013) Martin Pohl et al.   BIOSYSTEMS

Mitogenic Insulin Receptor-A Is Overexpressed in Human Hepatocellular Carcinoma due to EGFR-Mediated Dysregulation of RNA Splicing Factors

(2013) Hamza Chettouh et al.   CANCER RESEARCH

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion

(2013) C Braeutigam et al.   ONCOGENE

Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function

(2013) Supriya Sen et al.   Nature Communications

An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition

(2010) Claude C Warzecha et al.   EMBO JOURNAL

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

SFmap: a web server for motif analysis and prediction of splicing factor binding sites

(2010) I. Paz et al.   NUCLEIC ACIDS RESEARCH

Splicing factor and exon profiling across human tissues

(2010) Pierre de la Grange et al.   NUCLEIC ACIDS RESEARCH

Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences

(2010) Carmen Berasain   WORLD JOURNAL OF GASTROENTEROLOGY

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities

(2009) Y. Morozumi et al.   NUCLEIC ACIDS RESEARCH

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Tissue-specific splicing factor gene expression signatures

(2008) Ana Rita Grosso et al.   NUCLEIC ACIDS RESEARCH

The splicing-factor oncoprotein SF2/ASF activates mTORC1

(2008) R. Karni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA