Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination

Multiple Sclerosis

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Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis

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Regenerating CNS myelin — from mechanisms to experimental medicines

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Vitamin D receptor–retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation

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M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

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Mesenchymal Stem Cell Conditioning Promotes Rat Oligodendroglial Cell Maturation

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Mesenchymal stromal-cell transplants induce oligodendrocyte progenitor migration and remyelination in a chronic demyelination model

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The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis

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Stem Cell Ageing and Apoptosis

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Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

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Hepatocyte growth factor mediates mesenchymal stem cell–induced recovery in multiple sclerosis models

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Aging Effect on Neurotrophic Activity of Human Mesenchymal Stem Cells

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Mesenchymal Stem Cells

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Central nervous system remyelination in culture — A tool for multiple sclerosis research

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In vitro modeling of central nervous system myelination and remyelination

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A hyperactive piggyBac transposase for mammalian applications

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Aging alters tissue resident mesenchymal stem cell properties

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Mesenchymal Stem Cells Prime Proliferating Adult Neural Progenitors Toward an Oligodendrocyte Fate

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CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

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The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study Group

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Retinoid X receptor gamma signaling accelerates CNS remyelination

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Mesenchymal Stem Cells Promote Oligodendroglial Differentiation in Hippocampal Slice Cultures

(2009) Francisco J. Rivera et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis

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Effects of Direct Transplantation of Multipotent Mesenchymal Stromal/Stem Cells into the Demyelinated Spinal Cord

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Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors

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Multiple sclerosis

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Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

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