Article
Nursing
Heajin Cho, Ihn Sook Jeong
Summary: Increasing daily kangaroo mother care time was found to have a positive impact on reducing postpartum depression, but changes in mother-infant attachment were not related to contact time. Nurses should encourage mothers to participate in kangaroo mother care programs. Further studies considering various contacts, such as baby massage or bathing, are recommended.
NURSING & HEALTH SCIENCES
(2021)
Article
Clinical Neurology
Ozra Barooj-Kiakalaee, Seyed-Hamzeh Hosseini, Reza-Ali Mohammadpour-Tahmtan, Monirolsadate Hosseini-Tabaghdehi, Shayesteh Jahanfar, Zahra Esmaeili-Douki, Zohreh Shahhosseini
Summary: This study aimed to explore the relationship between paternal postpartum depression and maternal prenatal and postpartum depression, as well as marital satisfaction. The results showed that maternal prenatal and postpartum depression, as well as paternal prenatal depression, were associated with paternal postpartum depression. Additionally, marital satisfaction had a direct and indirect relationship with paternal postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Eydie L. Moses-Kolko, Layla Banihashemi, Alison E. Hipwell
Summary: The study found that hippocampal gray matter volume was inversely associated with positive maternal caregiving, while similar findings in the vmPFC did not remain significant after correction for multiple comparisons. ELS, particularly physical assault, was associated with reduced GM volumes, but was unrelated to observed maternal caregiving.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Mariana S. Mendonca, Paula M. Mangiavacchi, Ana Mendes, Sonia R. Loureiro, Rocio Martin-Santos, Leonardo S. Gloria, Wilson Marques, Silmara P. G. De Marco, Milton M. Kanashiro, Jaime E. C. Hallak, Jose A. S. Crippa, Alvaro F. L. Rios
Summary: This study aimed to evaluate the DNA methylation profile in maternal-infant depression in the regulatory regions of the FKBP5 and NR3C1 genes. The results showed an increased DNA methylation profile in the NR3C1 gene promoter in children with depression and children exposed to maternal depression. Additionally, a correlation of DNA methylation was observed between mothers and offspring exposed to maternal depression, indicating a possible intergenerational effect.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Family Studies
Vivian Chau, Rachel Dryer, Robyn Brunton
Summary: This study examines the relationship between maternal childhood abuse experience and mother-infant bonding disturbances during the postpartum period, and explores the mediating role of postnatal depression symptomatology and maternal self-efficacy. The results indicate that postnatal depression symptomatology and maternal self-efficacy fully mediate the relationship between psychological child abuse experience and mother-infant bonding disturbances. The study highlights the need to recognize comorbidity of abuse types in research.
CHILD ABUSE & NEGLECT
(2023)
Article
Psychiatry
Paraskevi Mavrogiorgou, Shirin Diop, Luc Turmes, Christina Specht, Simon Vanscheidt, Sabine Seehagen, Georg Juckel
Summary: The study found that mothers with postpartum depression are more likely to exhibit inactive, less positive, and more rejective behaviors towards their infants, as well as display disengaged affect. Distortions in mothers' mental functioning may influence dysfunctional mother-infant interactions.
PSYCHIATRY RESEARCH
(2022)
Article
Obstetrics & Gynecology
Yoko Okamoto, Satomi Doi, Aya Isumi, Junichi Sugawara, Kazuhisa Maeda, Shoji Satoh, Takeo Fujiwara, Nobuaki Mitsuda
Summary: The objective of this study was to develop and validate the Social Life Impact for Mother (SLIM) scale in order to identify mothers in Japan who need social support postpartum. The results showed that the SLIM scale, consisting of nine risk factors for postpartum social problems, predicted these problems with moderate accuracy. Therefore, obstetricians can use the SLIM scale during prenatal check-ups to detect mothers with postpartum social problems.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Psychiatry
Jonathan E. Handelzalts, Ilana S. Hairston, Sigal Levy, Naomi Orkaby, Haim Krissi, Yoav Peled
Summary: The aim of this study was to investigate the impact of the COVID-19 pandemic on the association between postpartum depression (PPD) and mother-infant bonding. The results showed that the correlation between mother-infant bonding and PPD significantly decreased during the pandemic, and only PPD was correlated with worry due to the pandemic. This suggests that emotions and cognitions related to motherhood may be more resilient to external pressures like a pandemic compared to affective states like PPD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychology, Clinical
Cristina Dragomir, Roxana Popescu, Monica Alisa Jurca, Ruxandra Laza, Roxana Ivan Florian, Ion Dragomir, Romeo Negrea, Marius Craina, Cristina Adriana Dehelean
Summary: This study aims to investigate the relationships between postpartum emotional manifestations and neonatal variables during hospitalization. The results show that the severity of depressive symptoms is higher in mothers whose newborns are hospitalized in NICUs, undergo oxygen therapy, are born prematurely, or have adjustment disorders. Similar findings are observed for anxiety. Additionally, there are strong correlations between neonatal variables and the mother's postpartum anxiety and depression. These findings provide insights for improving birth management and postnatal care.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2022)
Article
Clinical Neurology
S. Lubotzky-Gete, A. Ornoy, I Grotto, R. Calderon-Margalit
Summary: In a population-based historical cohort study conducted in Israel, it was found that postpartum depression (PPD) was associated with delays in child development across various domains, including language skills, personal social skills, fine motor skills, and gross motor skills. Future studies should validate these findings and intervention programs should be developed to minimize these gaps effectively.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Julia Frohberg, Antje Bittner, Susann Steudte-Schmiedgen, Juliane Junge-Hoffmeister, Susan Garthus-Niegel, Kerstin Weidner
Summary: The study found that there is no direct link between child maltreatment and mother-infant bonding, but this link is mediated by postpartum psychopathology. Emotional abuse has the strongest effect on mother-infant bonding, while physical abuse has a negative impact. Further research should include observational data to validate the results of self-report measures.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Obianuju O. Berry, Vanessa Babineau, Seonjoo Lee, Tianshu Feng, Pamela Scorza, Elizabeth A. Werner, Catherine Monk
Summary: The study showed that women with a history of childhood maltreatment had a limited response to interventions for preventing perinatal depression but still reported positive effects on infant daytime sleep.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Developmental
Jakob Johann Mueller
Summary: This study conducted two sub-studies and found that the stability of the mother's relationship with her partner is closely related to symptoms of postpartum mental disorders, quality of mother-child attachment, and inpatient treatment outcomes. Mothers with stressed relationships showed higher levels of symptom burden and impaired attachment, while those without a partner exhibited less impairment in mother-child attachment.
PRAXIS DER KINDERPSYCHOLOGIE UND KINDERPSYCHIATRIE
(2021)
Article
Psychology, Multidisciplinary
Hailey G. Holmgren, Laura Stockdale, Megan Gale, Sarah M. Coyne
Summary: The study found associations between symptoms of postpartum depression and parent-child dysfunctional interaction, parent and child problematic media use, and parental depressive symptoms. Parent-child dysfunctional interaction mediated the relationship between postpartum depression and parental depression, but not between postpartum depression and parent or child problematic media use.
COMPUTERS IN HUMAN BEHAVIOR
(2022)
Article
Psychology, Clinical
Simone N. Vigod, Greer Slyfield Cook, Kaeli Macdonald, Neesha Hussain-Shamsy, Hilary K. Brown, Claire de Oliveira, Kiana Torshizi, Pardeep K. Benipal, Sophie Grigoriadis, Catherine C. Classen, Cindy-Lee Dennis
Summary: This study supports the use of online, therapist-facilitated discussion board support group strategies for postpartum depression, indicating the need for a large-scale efficacy and cost-effectiveness evaluation of Mother Matters.
DEPRESSION AND ANXIETY
(2021)
Article
Obstetrics & Gynecology
Verena Wulff, Philip Hepp, Oliver T. Wolf, Percy Balan, Carsten Hagenbeck, Tanja Fehm, Nora K. Schaal
Summary: The study found that prenatal music and singing interventions have positive effects on maternal well-being and perceived closeness during pregnancy, improving mood and reducing stress. The singing group showed greater reduction in stress and improvement in emotional state compared to the music group.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
Article
Oncology
Mark Jesus M. Magbanua, Laura H. Hendrix, Terry Hyslop, William T. Barry, Eric P. Winer, Clifford Hudis, Deborah Toppmeyer, Lisa Anne Carey, Ann H. Partridge, Jean-Yves Pierga, Tanja Fehm, Jose Vidal-Martinez, Dimitrios Mavroudis, Jose A. Garcia-Saenz, Justin Stebbing, Paola Gazzaniga, Luis Manso, Rita Zamarchi, Maria Luisa Antelo, Leticia De Mattos-Arruda, Daniele Generali, Carlos Caldas, Elisabetta Munzone, Luc Dirix, Amy L. Delson, Harold J. Burstein, Misbah Qadir, Cynthia Ma, Janet H. Scott, Francois-Clement Bidard, John W. Park, Hope S. Rugo
Summary: This study identified 4 novel prognostic groups in metastatic breast cancer (MBC) based on similarities in circulating tumor cell (CTC) trajectory patterns during chemotherapy. Patients with intermediate+high CTCs (19.4%) had significantly poorer outcomes and may benefit from more effective treatment. This novel prognostic classification approach may guide future prospective clinical trials in MBC.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Obstetrics & Gynecology
Philip Hepp, Markus Fleisch, Kathrin Hasselbach, Tanja Fehm, Nora K. Schaal
Summary: Evidence shows that music has positive effects on patients and healthcare professionals in various medical scenarios. A study in Germany surveyed obstetricians and midwives, discovering that while music is more commonly played during vaginal births, there is a lack of equipment for music in operation theatres where caesarean sections take place. The majority of respondents believe that music is beneficial for team communication and patient communication.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
Correction
Oncology
Andreas Schneeweiss, Johannes Ettl, Diana Lueftner, Matthias W. Beckmann, Erik Belleville, Peter A. Fasching, Tanja N. Fehm, Matthias Geberth, Lothar Haeberle, Peyman Hadji, Andreas D. Hartkopf, Carsten Hielscher, Jens Huober, Eugen Ruckhaeberle, Wolfgang Janni, Hans Christian Kolberg, Christian M. Kurbacher, Evelyn Klein, Michael P. Lux, Volkmar Mueller, Naiba Nabieva, Friedrich Overkamp, Hans Tesch, Elena Laakmann, Florin-Andrei Taran, Julia Seitz, Christoph Thomssen, Michael Untch, Pauline Wimberger, Rachel Wuerstlein, Bernhard Volz, Diethelm Wallwiener, Markus Wallwiener, Sara Y. Brucker
Article
Public, Environmental & Occupational Health
Andreas Suhartoyo Winarno, Anne Mondal, Franca Christina Martignoni, Tanja Natascha Fehm, Monika Hampl
Summary: The current guidelines recommend bilateral inguinofemoral lymphadenectomy for unilaterally positive sentinel lymph nodes in vulvar cancer patients. A study suggests that tumor infiltrating cell depth may serve as an indication for bilateral lymphadenectomy. High-volume centers with experienced teams are crucial for successful management of vulvar cancer and sentinel node biopsy.
Article
Psychology, Multidisciplinary
Nora K. Schaal, Carsten Hagenbeck, Martina Helbig, Verena Wulff, Sarah Marthesheimer, Tanja Fehm, Philip Hepp
Summary: This study compared birth expectations and antenatal bonding of women pregnant prior to and during the COVID-19 pandemic. The results showed that women pregnant during the pandemic had higher fear of childbirth and lower antenatal bonding quality compared to those who were pregnant before the pandemic. The aspects of the pandemic that caused the highest worries for women were partner not being present during labor and no visitors being allowed in hospital.
JOURNAL OF REPRODUCTIVE AND INFANT PSYCHOLOGY
(2023)
Article
Obstetrics & Gynecology
Nora K. Schaal, Janine Zoellkau, Philip Hepp, Tanja Fehm, Carsten Hagenbeck
Summary: The survey revealed that during pregnancy, the majority of women (57.4%) are not in favor of receiving the COVID-19 vaccine, while breastfeeding women show higher willingness (39.5% are in favor). The willingness to be vaccinated is significantly related to the women's anxiety levels of getting infected and developing disease symptoms, with main reasons for vaccination hesitancy including limited vaccine-specific information and scientific evidence on vaccine safety, as well as fear of harming the fetus or infant.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Obstetrics & Gynecology
Janine Zoellkau, Carsten Hagenbeck, Kurt Hecher, Ulrich Pecks, Dietmar Schlembach, Arne Simon, Rolf Schloesser, Ekkehard Schleussner
Summary: The German Society of Gynecology and Obstetrics and the Society for Peri-/Neonatal Medicine have published and updated recommendations for the management of SARS-CoV-2 positive pregnancies and neonates. These recommendations aim to aid clinical decision making and have the endorsement of professional societies.
ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE
(2022)
Article
Obstetrics & Gynecology
Janine Zoellkau, Carsten Hagenbeck, Kurt Hecher, Ulrich Pecks, Dietmar Schlembach, Arne Simon, Rolf Schloesser, Ekkehard Schleussner
Summary: The German professional societies have published recommendations for the management of SARS-CoV-2 positive pregnancies and neonates, based on scientific data and expert consensus. These recommendations aim to assist clinical decision-making, with ultimate therapeutic responsibility resting with the local medical team.
ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE
(2022)
Article
Pediatrics
Henrike Hoermann, Anna Mokwa, Marcia Roeper, Roschan Salimi Dafsari, Felix Koestner, Carsten Hagenbeck, Ertan Mayatepek, Sebastian Kummer, Thomas Meissner
Summary: This study used video documentation to evaluate the sensitivity, specificity, and interobserver reliability of visualizable signs of neonatal hypoglycemia at different glucose concentrations in neonates. The results showed that clinical observation of signs is not sensitive or specific enough to detect neonatal hypoglycemia, and there are large differences between observers.
JOURNAL OF PEDIATRICS
(2022)
Article
Immunology
Natalie Heinen, Corinna Sophie Marheinecke, Clara Bessen, Arturo Blazquez-Navarro, Toralf Roch, Ulrik Stervbo, Moritz Anft, Carlos Plaza-Sirvent, Sandra Busse, Mara Kloehn, Jil Schrader, Elena Vidal Blanco, Doris Urlaub, Carsten Watzl, Markus Hoffmann, Stefan Poehlmann, Matthias Tenbusch, Eike Steinmann, Daniel Todt, Carsten Hagenbeck, Gert Zimmer, Wolfgang Ekkehard Schmidt, Daniel Robert Quast, Nina Babel, Ingo Schmitz, Stephanie Pfaender
Summary: Studies have shown that both homologous and heterologous prime-boost-boost vaccination strategies can induce robust humoral and T cell-mediated immunity against the Omicron variant of SARS-CoV-2. These findings can guide policy decisions.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Health Care Sciences & Services
Jan Hoffmann, Till Dresbach, Carsten Hagenbeck, Nadine Scholten
Summary: The closure of obstetric units in German hospitals is associated with factors such as the number of annual births, travel time between hospitals, availability of pediatrics department, and population density. Despite closures, accessibility to obstetric care remains good in most areas of Germany.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Immunology
Carsten Hagenbeck, Janine Zoellkau, Martina Helbig, Tanja Fehm, Nora K. Schaal
Summary: In Germany, pregnant and breastfeeding women were not included in the registration studies of COVID-19 vaccines, resulting in a delayed official recommendation for this vulnerable group. The survey revealed that the majority of participants obtained information about the recommendation autonomously (61.6%) and through the media (56.9%). Vaccination uptake increased after the official recommendation, but the involvement of healthcare professionals and education campaigns focusing on scientific evidence should be enhanced.
Article
Biochemistry & Molecular Biology
Huakang Zhou, Dilaware Khan, Norbert Gerdes, Carsten Hagenbeck, Majeed Rana, Jan Frederick Cornelius, Sajjad Muhammad
Summary: Inflammaging is a potential risk factor for cardiovascular diseases, leading to the development of thrombosis and atherosclerosis. Ethanol can induce inflammation and senescence, which are both implicated in cardiovascular diseases. In this study, colchicine was used to mitigate the damaging effects of ethanol on endothelial cells. It prevented senescence, reduced oxidative stress, and inhibited the activation of NF-κB and MAPKs in ethanol-treated endothelial cells. Colchicine ameliorated the ethanol-induced molecular events, resulting in attenuated senescence and senescence-associated secretory phenotype in endothelial cells.
Correction
Oncology
Hannah Asperger, Nadia Stamm, Berthold Gierke, Michael Pawlak, Ute Hofmann, Ulrich M. Zanger, Annamaria Marton, Robert L. Katona, Andrea Buhala, Csaba Vizler, Jan-Philipp Cieslik, Zaklina Kovacevic, Des R. Richardson, Eugen Ruckhaeberle, Dieter Niederacher, Tanja Fehm, Hans Neubauer, Marina Ludescher
Summary: A revised version of the paper has been published.
BREAST CANCER RESEARCH
(2021)