Article
Gastroenterology & Hepatology
Linda Y. Zhang, Oscar Hernandez Mondragon, Mathieu Pioche, Steven N. Steinway, Jose Nieto, Michael B. Ujiki, Vanessa N. VanDruff, Raymond E. Kim, Andrew Canakis, Marcel Tantau, Alina Tantau, Anamaria Pop, Jeremie Jacques, Michael Lajin, Pankaj Desai, Apurva Shrigiriwar, Michael Bejjani, Nikhil A. Kumta, Mouen A. Khashab
Summary: Background: Zenker's diverticulum peroral endoscopic myotomy (zPOEM) is a minimally invasive treatment strategy for Zenker's diverticulum. This study evaluated the use of zPOEM in the management of large Zenker's diverticulum. Results: The study demonstrated that zPOEM is a safe and effective treatment for large Zenker's diverticulum.
Article
Medicine, General & Internal
Aleksandra Budnicka, Wladyslaw Januszewicz, Andrzej B. Bialek, Michal Spychalski, Jaroslaw Regula, Michal F. Kaminski
Summary: Zenker's peroral endoscopic myotomy (Z-POEM) is a highly effective and safe treatment for symptomatic Zenker's diverticulum, especially among treatment-naive patients. The procedure has a high technical and clinical success rate, leading to significant symptom improvement.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Sarah S. Al Ghamdi, Jad Farha, Robert A. Moran, Mathieu Pioche, Frederic Moll, Dennis J. Yang, Oscar V. Hernandez Mondragon, Michael Ujiki, Harry Wong, Alina Tantau, Alireza Sedarat, M. Phillip Fejleh, Kenneth Chang, David P. Lee, Jose M. Nieto, Sherif Andrawes, Gregory G. Ginsberg, Monica Saumoy, Amol Bapaye, Parag Dashatwar, Mohamad Aghaie Meybodi, Ariana C. Lopez, Omid Sanaei, Muhammad N. Yousaf, Manol Jovani, Yervant Ichkhanian, Olaya I. Brewer Gutierrez, Vivek Kumbhari, Ashli K. O'Rourke, Eric J. Lentsch, B. Joseph Elmunzer, Mouen A. Khashab
Summary: This study compared the effectiveness of flexible and rigid endoscopic septotomy with that of Z-POEM for Zenker's diverticulum treatment. There was no significant difference in outcomes between the three treatment approaches. Rigid endoscopic septotomy had the highest rate of complications, while flexible endoscopic septotomy appeared to be the safest option.
Review
Surgery
Han Zhang, Shu Huang, Huifang Xia, Lei Shi, Xinyi Zeng, Jiao Jiang, Wensen Ren, Yan Peng, Muhan Lu, Xiaowei Tang
Summary: This meta-analysis assessed the safety and efficacy of Zenker's peroral endoscopic myotomy (Z-POEM) for Zenker's diverticulum (ZD). The results showed that Z-POEM had high technical and clinical success rates, and was superior to flexible endoscopic septotomy (FES) in clinical outcomes. However, further comparative studies with long-term follow-up are needed to confirm these findings.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Linda Yun Zhang, Peter Iung-Chiang Wu, Michal Szczesniak, Ian James Cook, Philip Ian Craig
Summary: Flexible endoscopic cricopharyngeal myotomy (FECM) can partially reverse the reduced distensibility of the cricopharyngeal muscle in patients with Zenker's diverticulum (ZD), and using the functional lumen imaging probe (FLIP) to measure CP distensibility during the procedure is safe and sensitive. Further studies are needed to establish precise metrics for predicting clinical response.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Jesse K. Kelley, Diana K. Haggerty, Giuseppe M. Zambito, Amy L. Banks-Venegoni
Summary: Our study demonstrates that general surgeons trained in endoscopy can perform endoscopic myotomies for Zenker's diverticula on a wide range of sizes, with favorable patient outcomes and few complications.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Xianhui Zeng, Shuai Bai, Yuhang Zhang, Liansong Ye, Xianglei Yuan, Bing Hu
Summary: This retrospective study reported the experience of using diverticular POEM (D-POEM) technique in the treatment of esophageal diverticulum, showing it to be a safe and effective approach with high technical success rate and significant improvement in symptomatic scores. The results suggest that D-POEM could be a promising method for managing esophageal diverticulum.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Chetan Mittal, David L. Diehl, Peter Draganov, Laith H. Jamil, Ammara Khalid, Harshit S. Khara, Vikas Khullar, Ryan Law, Simon K. Lo, Abraham Mathew, Ebrahim Mirakhor, Alireza Sedarat, Neil Sharma, Setareh Sharzehi, Anna Tavakkoli, Adarsh Thaker, Nirav Thosani, Dennis Yang, Christina Zelt, Mihir S. Wagh
Summary: Flexible endoscopic myotomy is an effective therapy for Zenker's diverticulum with high technical success rates and lower clinical success rates. The clinical success rate is higher with the use of a hook knife compared to a needle-knife and insulated tip knife.
Article
Gastroenterology & Hepatology
Shaimaa Elkholy, Mohamed El-Sherbiny, Roberto Delano-Alonso, Jose de Jesus Herrera-Esquivel, Carlos Valenzuela-Salazar, Andres Rodriguez-Parra, Ignacio Del Rio-Suarez, Jorge Vargas-Madrigal, Tarik Akar, Suleyman Gunay, Zaher Houmani, Bahri Abayli, Mohammad A. Elkady, Ahmed Alzamzamy, Mahmoud Wahba, Ahmad Madkour, Reem Ezzat Mahdy, Kareem Essam, Mouen A. Khashab
Summary: Z-POEM is a safe and effective modality for managing Zenker's diverticulum, achieving high technical success rate and significantly reducing symptom scores.
Article
Surgery
Eric Swei, Sridevi K. Pokala, Paul Menard-Katcher, Mihir S. Wagh
Summary: This study compared the outcomes of Z-POEM and traditional FES for the treatment of Zenker's diverticulum over a medium-term follow-up period. The results showed no significant differences in technical success, clinical success, and adverse event rates between the two methods. Therefore, Z-POEM can be considered as an effective technique for treating Zenker's diverticulum.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Omid Sanaei, Yervant Ichkhanian, Oscar V. Hernandez Mondragon, Jose Nieto, Arunkumar Krishnan, Marcel Tantau, Alina Tantau, Pankaj N. Desai, Gregory G. Ginsberg, Monica Saumoy, Ameya Deshmukh, Mikhail Attaar, Jad Farha, Manol Jovani, Sarah S. Al-Ghamdi, Michael Ujiki, Mouen A. Khashab
Summary: The study demonstrated that Z-POEM is technically feasible and effective in managing Zenker's diverticulum in patients with recurrent symptoms after prior failed interventions, with a high rate of clinical success and significant improvement in dysphagia symptoms. Adverse events were seen in a small percentage of patients.
Article
Gastroenterology & Hepatology
Enrique Rodriguez de Santiago, Yuto Shimamura, Mathieu Pioche, Nikos Eleftheriadis, Eduardo Albeniz, Robert Bechara, Philip Way Yan Chiu, Carlos Guarner-Argente, Alberto Herreros de Tejada, Hugo Uchima, Yusuke Fujiyoshi, Thierry Ponchon, Gonzalo Gonzalez-Gete, Simon Hew, Marianette Murzi-Pulgar, Virginia Matallana, Sofia Parejo-Carbonell, Fermin Estremera-Arevalo, Frederic Moll, Manabu Onimaru, Haruhiro Inoue
Summary: This study demonstrates that patients receiving antithrombotic therapy undergoing POEM are safe and effective, although there may be a higher risk of bleeding. The rates of major bleeding and thromboembolic events were higher in antithrombotics users, but clinical success rates and technical-related outcomes were similar in both groups.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Y. Ichkhanian, K. Vosoughi, M. Aghaie Meybodi, J. Jacques, A. Sethi, A. A. Patel, A. A. Aadam, J. R. Triggs, A. Bapaye, S. Dorwat, P. Benias, D. M. Chaves, M. Barret, R. J. Law, N. Browers, M. Pioche, P. Draganov, A. Kotzev, F. Estremera, E. Albeniz, M. B. Ujiki, Z. M. Callahan, I. M. Itani, O. G. Brewer, M. A. Khashab
Summary: G-POEM has been shown to be a safe and effective treatment for refractory gastroparesis, with adverse events typically being mild and managed conservatively. The experience of the endoscopist plays a significant role in reducing the incidence of adverse events.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Sunil Dacha, Hiroyuki Aihara, Gobind S. Anand, Kathryn R. Byrne, Prabhleen Chahal, Theodore James, Thomas E. Kowalski, Emad Qayed, Aparna Repaka, Mohammed Saadi, Sunil G. Sheth, Jason R. Taylor, Catharine M. Walsh, Renee L. Williams, Mihir S. Wagh
Summary: This document provides recommendations for a training curriculum on peroral endoscopic myotomy, intended for training directors, endoscopists, and trainees. It serves as an overview of techniques and a guide to published references, videos, and other resources for the trainer.
GASTROINTESTINAL ENDOSCOPY
(2021)
Review
Gastroenterology & Hepatology
Rami El Abiad, Elizabeth Brindise, Michael Bejjani, Bachir Ghandour, Mouen Khashab
Summary: Zenker diverticulum (ZD) is a common hypopharyngeal diverticulum in elderly males, presenting mainly with oropharyngeal dysphagia. Treatment options have advanced, focusing on complete transection of the cricopharyngeus muscle to restore normal bolus outflow. This review provides an overview of surgical and endoscopic treatments for ZD, particularly Zenker peroral endoscopic myotomy.
MINERVA GASTROENTEROLOGY
(2023)