Toward a better understanding of the mechanism of action for intra-arterial delivery of irinotecan from DC Bead(TM) (DEBIRI)

Fluorouracil, Leucovorin and Irinotecan Combined with Intra-Arterial Hepatic Infusion of Drug-Eluting Beads Preloaded with Irinotecan in Unresectable Colorectal Liver Metastases: Side Effects and Results of a Concomitant Treatment Schedule. Clinical Investigation

(2018) Domina Kekez et al.   TUMORI

Characterizing Drug-Polymer Bead Interactions Using Isothermal Titration Calorimetry

(2018) Tanya S. Swaine et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pilot Study Comparing Systemic and Tissue Pharmacokinetics of Irinotecan and Metabolites after Hepatic Drug-Eluting Chemoembolization

(2018) Elliot B. Levy et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Irinotecan-Eluting 75–150-μm Embolics Lobar Chemoembolization in Patients with Colorectal Cancer Liver Metastases: A Prospective Single-Center Phase I Study

(2018) Arash Fereydooni et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review

(2017) Dorte Lisbet Nielsen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hepatic intra-arterial injection of irinotecan drug eluting beads (DEBIRI) for patients with unresectable colorectal liver metastases: A systematic review

(2017) Olaguoke Akinwande et al.   SURGICAL ONCOLOGY-OXFORD

Polyethylene glycol microspheres loaded with irinotecan for arterially directed embolic therapy of metastatic liver cancer

(2017) Giammaria Fiorentini et al.   World Journal of Gastrointestinal Oncology

An in-vitro evaluation of three types of drug-eluting microspheres loaded with irinotecan

(2016) Philippe L. Pereira et al.   ANTI-CANCER DRUGS

Review of the Clinical Evidence for the Use of DEBIRI in the Treatment of Colorectal Metastatic Disease

(2016) Shamar Young et al.   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY

PARAGON II – A single arm multicentre phase II study of neoadjuvant therapy using irinotecan bead in patients with resectable liver metastases from colorectal cancer

(2016) R.P. Jones et al.   EJSO

A pilot study employing hepatic intra-arterial irinotecan injection of drug-eluting beads as salvage therapy in liver metastatic colorectal cancer patients without extrahepatic involvement: the first southern Italy experience

(2016) Girolamo Ranieri et al.   OncoTargets and Therapy

A review of conventional and drug-eluting chemoembolization in the treatment of colorectal liver metastases: principles and proof

(2015) David M Liu et al.   Future Oncology

DC BeadM1™: towards an optimal transcatheter hepatic tumour therapy

(2015) Andrew L. Lewis et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Safety and Efficacy Compared between Irinotecan-Loaded Microspheres HepaSphere and DC Bead in a Model of VX2 Liver Metastases in the Rabbit

(2015) Julien Namur et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Direct Quantification and Comparison of Intratumoral Hypoxia following Transcatheter Arterial Embolization of VX2 Liver Tumors with Different Diameter Microspheres

(2015) Elliot B. Levy et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Evaluation of the Plasmatic and Parenchymal Elution Kinetics of Two Different Irinotecan-Loaded Drug-Eluting Embolics in a Pig Model

(2015) Daniel M. Gnutzmann et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Complete pathological response of unresectable liver metastases from colorectal cancer after trans-arterial chemoembolization with drug-eluting beads loaded with irinotecan (DEBIRI) and concomitant systemic FOLFOX: A case report from the FFCD 1201 trial

(2015) Simon Pernot et al.   Clinics and Research in Hepatology and Gastroenterology

Comparative Effectiveness of Hepatic Artery Based Therapies for Unresectable Colorectal Liver Metastases: A Meta-Analysis

(2015) Anthony J. Zacharias et al.   PLoS One

Small Versus Large-Sized Drug-Eluting Beads (DEBIRI) for the Treatment of Hepatic Colorectal Metastases: A Propensity Score Matching Analysis

(2014) Olaguoke K. Akinwande et al.   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY

Pharmacokinetics and Antitumor Efficacy of Chemoembolization Using 40 µm Irinotecan-Loaded Microspheres in a Rabbit Liver Tumor Model

(2014) Toshihiro Tanaka et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Transarterial Treatment of Colorectal Cancer Liver Metastases with Irinotecan-Loaded Drug-Eluting Beads: Technical Recommendations

(2014) Riccardo Lencioni et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study

(2013) R. P. Jones et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Radiological assessment of response to neoadjuvant transcatheter hepatic therapy with irinotecan-eluting beads (DEBIRI®) for colorectal liver metastases does not predict tumour destruction or long-term outcome

(2013) R.P. Jones et al.   EJSO

Transarterial chemoembolization of unresectable systemic chemotherapy-refractory liver metastases from colorectal cancer: Long-term results over a 10-year period

(2013) Tatjana Gruber-Rouh et al.   INTERNATIONAL JOURNAL OF CANCER

Development of a combination drug-eluting bead

(2012) Richard E.J. Forster et al.   ANTI-CANCER DRUGS

Bradycardia Associated With Drug-Eluting Beads Loaded With Irinotecan (DEBIRI) Infusion for Colorectal Liver Metastases

(2012) Uei Pua   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY

Irinotecan Loaded in Eluting Beads: Preclinical Assessment in a Rabbit VX2 Liver Tumor Model

(2012) Pramod P. Rao et al.   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI)

(2012) K. EICHLER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Locoregional drug delivery using image-guided intra-arterial drug eluting bead therapy

(2012) Andrew L. Lewis et al.   JOURNAL OF CONTROLLED RELEASE

Irinotecan Drug-Eluting Beads in the Treatment of Chemo-Naive Unresectable Colorectal Liver Metastasis with Concomitant Systemic Fluorouracil and Oxaliplatin: Results of Pharmacokinetics and Phase I Trial

(2012) Robert C. G. Martin et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Feasibility, safety and pharmacokinetic study of hepatic administration of drug-eluting beads loaded with irinotecan (DEBIRI) followed by intravenous administration of irinotecan in a porcine model

(2012) Andrew L. Lewis et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Transcatheter Treatment of Hepatocellular Carcinoma with Doxorubicin-loaded DC Bead (DEBDOX): Technical Recommendations

(2011) Riccardo Lencioni et al.   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY

Abstract No. 242: Small (70–150 micron) irinotecan drug eluting bead treatment in the management of hepatic metastatic disease: Clinical rationale and pilot data

(2011) L.R. Kelly et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Radiopaque Drug-Eluting Beads for Transcatheter Embolotherapy: Experimental Study of Drug Penetration and Coverage in Swine

(2011) Matthew R. Dreher et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer

(2010) Richard E. J. Forster et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Comparative Study of Chemoembolization Loadable Beads: In vitro Drug Release and Physical Properties of DC Bead and Hepasphere Loaded with Doxorubicin and Irinotecan

(2010) Olivier Jordan et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

DC Bead™: a major development in the toolbox for the interventional oncologist

(2009) Andrew L Lewis   Expert Review of Medical Devices

Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report

(2009) Robert CG Martin et al.   World Journal of Surgical Oncology

Stability of irinotecan-loaded drug eluting beads (DC BeadTM) used for transarterial chemoembolization

(2009) Jeanette Kaiser et al.   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Chemoembolisation of rat colorectal liver metastases with drug eluting beads loaded with irinotecan or doxorubicin

(2008) Ergül Eyol et al.   CLINICAL & EXPERIMENTAL METASTASIS

Pathologic Response to Preoperative Chemotherapy: A New Outcome End Point After Resection of Hepatic Colorectal Metastases

(2008) Dan G. Blazer et al.   JOURNAL OF CLINICAL ONCOLOGY

Preservation of the active lactone form of irinotecan using drug eluting beads for the treatment of colorectal cancer metastases

(2007) Yiqing Tang et al.   JOURNAL OF CONTROLLED RELEASE