Kartogenin preconditioning commits mesenchymal stem cells to a precartilaginous stage with enhanced chondrogenic potential by modulating JNK and β-catenin−related pathways

Intra-articular injection of kartogenin-conjugated polyurethane nanoparticles attenuates the progression of osteoarthritis

(2018) Wenshuai Fan et al.   DRUG DELIVERY

Tracheal replacement

(2018) Harry Etienne et al.   EUROPEAN RESPIRATORY JOURNAL

Recent advances in kartogenin for cartilage regeneration

(2018) Gaorui Cai et al.   JOURNAL OF DRUG TARGETING

Human Wharton's Jelly-Derived Stem Cells Display a Distinct Immunomodulatory and Proregenerative Transcriptional Signature Compared to Bone Marrow-Derived Stem Cells

(2018) Raf Donders et al.   STEM CELLS AND DEVELOPMENT

Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-κB pathway

(2018) Xiaoyan Chen et al.   Cell Death & Disease

LncRNA KCNQ1OT1 promotes osteogenic differentiation to relieve osteolysis via Wnt/β-catenin activation

(2018) Xuren Gao et al.   Cell and Bioscience

Restoring tracheal defects in a rabbit model with tissue engineered patches based on TGF-β3-encapsulating electrospun poly(l-lactic acid-co-ε-caprolactone)/collagen scaffolds

(2018) Hui Jing et al.   Artificial Cells Nanomedicine and Biotechnology

Enhanced osteogenic differentiation and bone regeneration of poly(lactic-co-glycolic acid) by graphene via activation of PI3K/Akt/GSK-3β/β-catenin signal circuit

(2018) Xiaowei Wu et al.   Biomaterials Science

Application of kartogenin for musculoskeletal regeneration

(2017) Gun-Il Im   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Evaluation of the potential of rhTGF- β3 encapsulated P(LLA-CL)/collagen nanofibers for tracheal cartilage regeneration using mesenchymal stems cells derived from Wharton's jelly of human umbilical cord

(2017) Jing Wang et al.   Materials Science & Engineering C-Materials for Biological Applications

Slide tracheoplasty in 81 children

(2017) Hengyi Zhang et al.   MEDICINE

Polyethylene glycol modified PAMAM dendrimer delivery of kartogenin to induce chondrogenic differentiation of mesenchymal stem cells

(2017) Qing Hu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Characterization and use of Equine Bone Marrow Mesenchymal Stem Cells in Equine Cartilage Engineering. Study of their Hyaline Cartilage Forming Potential when Cultured under Hypoxia within a Biomaterial in the Presence of BMP-2 and TGF-ß1

(2017) Thomas Branly et al.   Stem Cell Reviews and Reports

Characterization and use of Equine Bone Marrow Mesenchymal Stem Cells in Equine Cartilage Engineering. Study of their Hyaline Cartilage Forming Potential when Cultured under Hypoxia within a Biomaterial in the Presence of BMP-2 and TGF-ß1

(2017) Thomas Branly et al.   Stem Cell Reviews and Reports

Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells as a Potential Source for Cartilage and Bone Regeneration: An In Vitro Study

(2017) A. Marmotti et al.   Stem Cells International

Chondrogenesis of Embryonic Stem Cell-Derived Mesenchymal Stem Cells Induced by TGFβ1 and BMP7 Through Increased TGFβ Receptor Expression and Endogenous TGFβ1 Production

(2016) Patrick T. Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation

(2016) Verena Dexheimer et al.   Scientific Reports

Tissue-Engineered Tracheal Replacement in a Child: A 4-Year Follow-Up Study

(2015) N. J. Hamilton et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Cross-talk between TGF-beta/SMAD and integrin signaling pathways in regulating hypertrophy of mesenchymal stem cell chondrogenesis under deferral dynamic compression

(2015) Tianting Zhang et al.   BIOMATERIALS

Kartogenin, transforming growth factor-β1 and bone morphogenetic protein-7 coordinately enhance lubricin accumulation in bone-derived mesenchymal stem cells

(2015) Chun Liu et al.   CELL BIOLOGY INTERNATIONAL

Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin

(2014) Rebekah S. Decker et al.   DEVELOPMENTAL BIOLOGY

Transforming Growth Factor-β1 (TGF-β1) Induces Mouse Precartilaginous Stem Cell Proliferation through TGF-β Receptor II (TGFRII)-Akt-β-Catenin Signaling

(2014) Li Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Electrospun Collagen/Poly(L-lactic acid-co-ε-caprolactone) Hybrid Nanofibrous Membranes Combining with Sandwich Construction Model for Cartilage Tissue Engineering

(2013) Xiaomin He et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Runx1 Is Critical for PTH-induced Onset of Mesenchymal Progenitor Cell Chondrogenic Differentiation

(2013) Jinwu Wang et al.   PLoS One

Growth Differentiation Factor-5 Enhances In Vitro Mesenchymal Stromal Cell Chondrogenesis and Hypertrophy

(2013) Cynthia M. Coleman et al.   STEM CELLS AND DEVELOPMENT

MicroRNA-34a Modulates Cytoskeletal Dynamics through Regulating RhoA/Rac1 Cross-talk in Chondroblasts

(2012) Dongkyun Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study

(2012) Martin J Elliott et al.   LANCET

A Stem Cell-Based Approach to Cartilage Repair

(2012) K. Johnson et al.   SCIENCE