Review
Rheumatology
Francesca Ingegnoli, Ariane L. Herrick, Tommaso Schioppo, Francesca Bartoli, Nicola Ughi, John D. Pauling, Alberto Sulli, Maurizio Cutolo, Vanessa Smith
Summary: This study aimed to seek consensus on reporting standards in nailfold videocapillaroscopy (NVC) methodology and propose a pragmatic checklist. Through a Delphi exercise, 80 participants from 31 countries reached agreement on minimum reporting standards for NVC, covering patient preparation, device description, and examination details.
Article
Rheumatology
Karin Melsens, Maurizio Cutolo, Dieneke Schonenberg-Meinema, Ivan Foeldvari, Maria C. Leone, Yora Mostmans, Valerie Badot, Rolando Cimaz, Joke Dehoorne, Ellen Deschepper, Tracy Frech, Johanna Hernandez-Zapata, Francesca Ingegnoli, Archana Khan, Dorota Krasowska, Hartwig Lehmann, Ashima Makol, Miguel A. Mesa-Navas, Malgorzata Michalska-Jakubus, Ulf Muller-Ladner, Laura Nuno-Nuno, Rebecca Overbury, Carmen Pizzorni, Mislav Radic, Divya Ramadoss, Angelo Ravelli, Silvia Rosina, Clara Udaondo, Merlijn J. van den Berg, Ariane L. Herrick, Alberto Sulli, Vanessa Smith
Summary: This study aimed to standardly assess and describe nailfold videocapillaroscopy (NVC) assessment in children and adolescents with juvenile rheumatic and musculoskeletal diseases (jRMD) vs healthy controls (HCs). The results showed significant differences in NVC assessment between jRMD subgroups and HCs.
Article
Rheumatology
Martin Eden, Sarah Wilkinson, Andrea Murray, Praveen Gurunath Bharathi, Andy Vail, Chris J. Taylor, Katherine Payne, Ariane L. Herrick
Summary: There are barriers to the use of nailfold capillaroscopy as a diagnostic tool for patients with Raynaud's phenomenon in UK rheumatology centers, including lack of equipment, image acquisition experience, and image interpretation expertise. Most rheumatologists are interested in an internet-based standardized automated system for reporting nailfold capillaroscopy images.
Review
Rheumatology
Ariane L. Herrick, Michael Berks, Chris J. Taylor
Summary: This review examines the potential and challenges of quantitative nailfold capillaroscopy, particularly in the context of systemic sclerosis. It highlights the importance of quantitative analysis for precise discrimination between normal and abnormal capillaries and reliable measurement of disease progression and treatment response. Suggestions for future steps include increased utilization of this technique in clinical practice and its potential as a biomarker in large-scale prospective research studies.
Article
Medicine, General & Internal
Maria Maddalena Sirufo, Lina Maria Magnanimi, Lia Ginaldi, Massimo De Martinis
Summary: Raynaud's phenomenon is a common clinical finding that can be distinguished using nailfold videocapillaroscopy. However, the variety of nomenclature and the presence of non specific vascular changes make it difficult to differentiate different types of Raynaud's phenomenon.
CURRENT MEDICAL RESEARCH AND OPINION
(2022)
Article
Biology
Maria Maddalena Sirufo, Alessandra Catalogna, Francesca De Pietro, Lia Ginaldi, Massimo De Martinis
Summary: Drummers are at risk of microvascular abnormalities and Raynaud's phenomenon due to prolonged exposure to vibration. Nailfold video capillaroscopy is a useful tool for detecting and monitoring these issues with low cost and high sensitivity.
Article
Rheumatology
Greta Pacini, Andrea Pogna, Monica Pendolino, Carmen Pizzorni, Luca Carmisciano, Emanuele Gotelli, Alberto Sulli, Sabrina Paolino, Carlotta Schenone, Vanessa Smith, Maurizio Cutolo
Summary: This study describes an NVC 'prescleroderma signature' to potentially identify RP patients later developing a 'scleroderma pattern'.
Article
Medicine, General & Internal
Gabriella Nagy, Laszlo Czirjak, Gabor Kumanovics
Summary: Nailfold video capillaroscopy (NVC) is a useful tool for measuring capillary density (CD) and capillary morphology, mainly in systemic sclerosis (SSc). The presence of another CTD in SSc did not influence CD or morphology. An SSc pattern may also be present in CTDs other than SSc.
Article
Rheumatology
Saeedeh Shenavandeh, Mehrnoush Ajri, Sahand Hamidi
Summary: Capillaroscopy is a useful tool for distinguishing primary and secondary causes in patients with RP. This retrospective cohort study aimed to evaluate the causes of RP in a specific area and identify prognostic factors indicating a definite CTD or remaining a UCTD. The study found that the most prevalent causes of secondary RP were UCTD and SSc, and certain capillaroscopy and laboratory results could serve as predictive markers for the transition from UCTD to CTD.
Review
Medicine, General & Internal
Magdalena Maciejewska, Mariusz Sikora, Cezary Maciejewski, Rosanna Alda-Malicka, Joanna Czuwara, Lidia Rudnicka
Summary: Raynaud's phenomenon is a vascular condition that can be primary or secondary to other medical conditions. Systemic sclerosis is a common cause of secondary Raynaud's phenomenon.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dermatology
Bartosz Miziolek, Robert Pieczyrak, Karina Polak, Aleksandra Fratczak, Aleksandra Jedlecka, Anida Grosicka, Beata Bergler-Czop
Summary: Short courses on NFC can enhance the classification ability of capillaroscopic images, even for medical staff without previous experience. Recognizing capillaroscopic abnormalities seems to be easier than obtaining confidence in evaluating pictures with a normal pattern.
SKIN RESEARCH AND TECHNOLOGY
(2023)
Article
Medicine, General & Internal
Sambit Sundaray, Siddhartha Mishra, Subhash Chandra Dash, Naba Kishore Sundaray
Summary: This study assessed the nailfold capillaroscopic findings in Indian subjects with secondary Raynaud and compared them with healthy subjects. The results showed that both quantitative and qualitative parameters were significantly associated with secondary Raynaud, with scleroderma pattern being predominant in systemic sclerosis and mixed connective tissue diseases, and non-specific pattern being predominantly found in systemic lupus erythematosus and dermatomyositis.
RAMBAM MAIMONIDES MEDICAL JOURNAL
(2022)
Review
Rheumatology
Yasser El Miedany, Sherif Ismail, Mary Wadie, Mohammed Hassan
Summary: The lack of familiarity with nailfold capillaroscopy technique and interpretation of its outcomes has hindered its utilization in standard clinical practice. However, as a non-invasive technique, nailfold capillaroscopy holds great potential as an outcome measure in research and for identifying underlying connective tissue diseases.
CLINICAL RHEUMATOLOGY
(2022)
Article
Rheumatology
Susan L. Murphy, Alain Lescoat, Mary Alore, Michael Hughes, John D. Pauling, Maya Sabbagh, Dinesh Khanna
Summary: There are differences in how people with primary and secondary RP define RP, with primary RP patients more likely to focus on the impact on quality of life and pain, while secondary RP patients tend to emphasize specific body parts and management of attacks. These findings have implications for assessing RP outcomes in different patient populations.
CLINICAL RHEUMATOLOGY
(2021)
Review
Medicine, General & Internal
Fahidah Alenzi, David P. D'Cruz
Summary: This case report highlights a potential correlation between reversible cerebral vasoconstriction syndrome (RCVS) and Raynaud's phenomenon, as well as a connection between RCVS and autoimmune rheumatic diseases. Physicians should be aware of neurological abnormalities, such as headaches, in patients with inactive clinical status of autoimmune rheumatic diseases to improve patient care and outcomes.