An updated patent review on P-glycoprotein inhibitors (2011-2018)

Design and Synthesis of New Selective P-gp Substrates and Inhibitors

(2016) Mariangela Cantore et al.   CURRENT PHARMACEUTICAL DESIGN

Whole-Body Distribution and Radiation Dosimetry of 11C-Elacridar and 11C-Tariquidar in Humans

(2016) M. Bauer et al.   JOURNAL OF NUCLEAR MEDICINE

Radiopharmaceuticals for assessing ABC transporters at the blood-brain barrier

(2015) RM Raaphorst et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Tariquidar inhibits P-glycoprotein drug efflux but activates ATPase activity by blocking transition to an open conformation

(2014) Tip W. Loo et al.   BIOCHEMICAL PHARMACOLOGY

SAR Studies on Tetrahydroisoquinoline Derivatives: The Role of Flexibility and Bioisosterism To Raise Potency and Selectivity toward P-glycoprotein

(2014) Elena Capparelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Investigation of the Effect of the Uneven Distribution of CYP3A4 and P-Glycoprotein in the Intestine on the Barrier Function against Xenobiotics: A Simulation Study

(2013) Takao Watanabe et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Comparative evaluation of two dye probes in the rat everted gut sac model for unambiguous classification of P-gp substrate and inhibitor

(2012) Maria Grazia Perrone et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

The emerging role of P-glycoprotein inhibitors in drug delivery: a patent review

(2011) Naseem Akhtar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Substrates, Inhibitors and Activators of P-glycoprotein: Candidates for Radiolabeling and Imaging Perspectives

(2010) Nicola A. Colabufo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[11C]verapamil PET

(2009) Claudia Kuntner et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Synthesis and Preclinical Evaluation of Novel PET Probes for P-Glycoprotein Function and Expression

(2009) Aren van Waarde et al.   JOURNAL OF MEDICINAL CHEMISTRY

Imaging of Cyclosporine Inhibition of P-Glycoprotein Activity Using 11C-Verapamil in the Brain: Studies of Healthy Humans

(2009) M. Muzi et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of [11C]laniquidar as a tracer of P-glycoprotein: radiosynthesis and biodistribution in rats

(2009) Gert Luurtsema et al.   NUCLEAR MEDICINE AND BIOLOGY

Tariquidar-Induced P-Glycoprotein Inhibition at the Rat Blood-Brain Barrier Studied with (R)-11C-Verapamil and PET

(2008) J. P. Bankstahl et al.   JOURNAL OF NUCLEAR MEDICINE