Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer

Published 2019 View Full Article

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Title
Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer
Authors
Keywords
Cytochromes P450, Aromatase, Molecular dynamics, Aromatase inhibitors, Docking, Breast cancer, Resistance onset, Mixed inhibition mechanism
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 168, Issue -, Pages 253-262
Publisher
Elsevier BV
Online
2019-02-14
DOI
10.1016/j.ejmech.2019.02.045

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