(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist

Published 2019 View Full Article

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Title
(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist
Authors
Keywords
Pain, Multitarget, Asymmetric synthesis, Radioligand competition binding, BRET, G-protein, β-arrestin, Tail flick test
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 168, Issue -, Pages 189-198
Publisher
Elsevier BV
Online
2019-02-19
DOI
10.1016/j.ejmech.2019.02.043

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