In VitroFunctional Analyses of Infrequent Nucleotide Variants in the Lactase Enhancer Reveal Different Molecular Routes to Increased Lactase Promoter Activity and Lactase Persistence

Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging

(2016) Viviane Labrie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging

(2016) Viviane Labrie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Diversity of lactase persistence in African milk drinkers

(2015) Bryony Leigh Jones et al.   HUMAN GENETICS

Functional Significance of Single Nucleotide Polymorphisms in the Lactase Gene in Diverse US Patients and Evidence for a Novel Lactase Persistence Allele at −13909 in Those of European Ancestry

(2015) Nana Yaa Baffour-Awuah et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Genetic Origins of Lactase Persistence and the Spread of Pastoralism in Africa

(2014) Alessia Ranciaro et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Diversity of Lactase Persistence Alleles in Ethiopia: Signature of a Soft Selective Sweep

(2013) Bryony L. Jones et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The human lactase persistence-associated SNP −13910*T enables in vivo functional persistence of lactase promoter–reporter transgene expression

(2012) Lin Fang et al.   HUMAN GENETICS

Several Different Lactase Persistence Associated Alleles and High Diversity of the Lactase Gene in the Admixed Brazilian Population

(2012) Deise C. Friedrich et al.   PLoS One

Current and emerging approaches to define intestinal epithelium-specific transcriptional networks

(2011) Anders Krüger Olsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors

(2011) Peter C. Hollenhorst et al.   Annual Review of Biochemistry

The −14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activity

(2011) Tine G. K. Jensen et al.   HUMAN GENETICS

Herders of Indian and European Cattle Share Their Predominant Allele for Lactase Persistence

(2011) Irene Gallego Romero et al.   MOLECULAR BIOLOGY AND EVOLUTION

−13915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1

(2010) Lynne C. Olds et al.   HUMAN GENETICS

Genome-wide Analysis of CDX2 Binding in Intestinal Epithelial Cells (Caco-2)

(2010) Mette Boyd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple Rare Variants as a Cause of a Common Phenotype: Several Different Lactase Persistence Associated Alleles in a Single Ethnic Group

(2009) Catherine J. E. Ingram et al.   JOURNAL OF MOLECULAR EVOLUTION

Independent Introduction of Two Lactase-Persistence Alleles into Human Populations Reflects Different History of Adaptation to Milk Culture

(2008) Nabil Sabri Enattah et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Lactose digestion and the evolutionary genetics of lactase persistence

(2008) Catherine J. E. Ingram et al.   HUMAN GENETICS