Significance of AZD1152 as a potential treatment against Aurora B overexpression in acute promyelocytic leukemia
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Significance of AZD1152 as a potential treatment against Aurora B overexpression in acute promyelocytic leukemia
Authors
Keywords
Aurora B kinase, AZD1152, Acute promyelocytic leukemia, p73, Cell cycle arrest, Apoptosis
Journal
ANNALS OF HEMATOLOGY
Volume 95, Issue 7, Pages 1031-1042
Publisher
Springer Nature
Online
2016-04-19
DOI
10.1007/s00277-016-2670-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy
- (2014) Ali Zekri et al. TUMOR BIOLOGY
- Molecular Pathways: Induction of Polyploidy as a Novel Differentiation Therapy for Leukemia
- (2013) D. S. Krause et al. CLINICAL CANCER RESEARCH
- Gene Amplification and Overexpression of Aurora-C in Breast and Prostate Cancer Cell Lines
- (2013) Ali Zekri et al. ONCOLOGY RESEARCH
- Cell division control by the Chromosomal Passenger Complex
- (2012) Maike S. van der Waal et al. EXPERIMENTAL CELL RESEARCH
- Mitosis-targeted anti-cancer therapies: where they stand
- (2012) K-S Chan et al. Cell Death & Disease
- Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia
- (2011) B. Lowenberg et al. BLOOD
- Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer
- (2011) A Azzariti et al. BRITISH JOURNAL OF CANCER
- Phase II Study of Single-Agent Arsenic Trioxide for the Front-Line Therapy of Acute Promyelocytic Leukemia
- (2011) Ardeshir Ghavamzadeh et al. JOURNAL OF CLINICAL ONCOLOGY
- Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells
- (2011) Duo-Rong Xu et al. Journal of Translational Medicine
- A Phase I study to assess the safety, pharmacokinetics and efficacy of barasertib (AZD1152), an Aurora B kinase inhibitor, in Japanese patients with advanced acute myeloid leukemia
- (2011) Kosuke Tsuboi et al. LEUKEMIA RESEARCH
- PML-RARα/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia
- (2010) Joost H.A. Martens et al. CANCER CELL
- The FLT3 Internal Tandem Duplication Mutation Is a Secondary Target of the Aurora B Kinase Inhibitor AZD1152-HQPA in Acute Myelogenous Leukemia Cells
- (2010) M. Grundy et al. MOLECULAR CANCER THERAPEUTICS
- AZD1152 Rapidly and Negatively Affects the Growth and Survival of Human Acute Myeloid Leukemia Cells In vitro and In vivo
- (2009) A. Oke et al. CANCER RESEARCH
- p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells
- (2009) Takayuki Ikezoe et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts
- (2008) E. Walsby et al. HAEMATOLOGICA
- Preclinical evaluation of M30 and M65 ELISAs as biomarkers of drug induced tumor cell death and antitumor activity
- (2008) J. Cummings et al. MOLECULAR CANCER THERAPEUTICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started