Role of Cdx factors in early mesodermal fate decisions

Transcription factor-dependent ‘anti-repressive’ mammalian enhancers exclude H3K27me3 from extended genomic domains

(2017) Madhurima Saxena et al.   GENES & DEVELOPMENT

Gdf11/Smad signalling and Cdx proteins cooperate to activate the Hoxc8 early enhancer in HepG2 cells

(2017) Stephen J. Gaunt   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cdx2 Regulates Gene Expression through Recruitment of Brg1-associated Switch-Sucrose Non-fermentable (SWI-SNF) Chromatin Remodeling Activity

(2017) Thinh T. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs

(2016) Jyoti Rao et al.   Cell Stem Cell

Resolving early mesoderm diversification through single-cell expression profiling

(2016) Antonio Scialdone et al.   NATURE

Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche

(2016) Shilu Amin et al.   Cell Reports

Brg1 modulates enhancer activation in mesoderm lineage commitment

(2015) J. M. Alexander et al.   DEVELOPMENT

Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence

(2015) T. Org et al.   EMBO JOURNAL

NANOG and CDX2 Pattern Distinct Subtypes of Human Mesoderm during Exit from Pluripotency

(2014) Sasha Mendjan et al.   Cell Stem Cell

Early patterning and specification of cardiac progenitors in gastrulating mesoderm

(2014) W Patrick Devine et al.   eLife

Mesp1 Patterns Mesoderm into Cardiac, Hematopoietic, or Skeletal Myogenic Progenitors in a Context-Dependent Manner

(2013) Sunny Sun-Kin Chan et al.   Cell Stem Cell

Scl Represses Cardiomyogenesis in Prospective Hemogenic Endothelium and Endocardium

(2012) Ben Van Handel et al.   CELL

Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming

(2012) Paul W. Burridge et al.   Cell Stem Cell

Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence

(2012) C. van Rooijen et al.   DEVELOPMENT

Cdx function is required for maintenance of intestinal identity in the adult

(2012) Alexa Hryniuk et al.   DEVELOPMENTAL BIOLOGY

Generation and live imaging of an endogenous Cdx2 reporter mouse line

(2012) Katie McDole et al.   GENESIS

Intestinal Master Transcription Factor CDX2 Controls Chromatin Access for Partner Transcription Factor Binding

(2012) M. P. Verzi et al.   MOLECULAR AND CELLULAR BIOLOGY

Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA

(2012) Jeremy M Simon et al.   Nature Protocols

Cdx mediates neural tube closure through transcriptional regulation of the planar cell polarity gene Ptk7

(2011) Joanne G. A. Savory et al.   DEVELOPMENT

Cdx2 determines the fate of postnatal intestinal endoderm

(2011) E. J. Stringer et al.   DEVELOPMENT

Interactions between Cdx genes and retinoic acid modulate early cardiogenesis

(2011) Claudia Lengerke et al.   DEVELOPMENTAL BIOLOGY

Cdx regulates Dll1 in multiple lineages

(2011) Stephanie Grainger et al.   DEVELOPMENTAL BIOLOGY

Essential and Redundant Functions of Caudal Family Proteins in Activating Adult Intestinal Genes

(2011) M. P. Verzi et al.   MOLECULAR AND CELLULAR BIOLOGY

Cdx2 regulates patterning of the intestinal epithelium

(2010) Stephanie Grainger et al.   DEVELOPMENTAL BIOLOGY

Differentiation-Specific Histone Modifications Reveal Dynamic Chromatin Interactions and Partners for the Intestinal Transcription Factor CDX2

(2010) Michael P. Verzi et al.   DEVELOPMENTAL CELL

Brachyury establishes the embryonic mesodermal progenitor niche

(2010) B. L. Martin et al.   GENES & DEVELOPMENT

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE

Cdx2 regulation of posterior development through non-Hox targets

(2009) J. G. A. Savory et al.   DEVELOPMENT

Cdx1 and Cdx2 are functionally equivalent in vertebral patterning

(2009) Joanne G.A. Savory et al.   DEVELOPMENTAL BIOLOGY

Establishment of Intestinal Identity and Epithelial-Mesenchymal Signaling by Cdx2

(2009) Nan Gao et al.   DEVELOPMENTAL CELL

Cdx and Hox Genes Differentially Regulate Posterior Axial Growth in Mammalian Embryos

(2009) Teddy Young et al.   DEVELOPMENTAL CELL

Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis

(2009) Laura Faas et al.   DEVELOPMENTAL DYNAMICS

Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells

(2009) Nobutake Yamamichi et al.   EXPERIMENTAL CELL RESEARCH

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

Mesp1 Acts as a Master Regulator of Multipotent Cardiovascular Progenitor Specification

(2008) Antoine Bondue et al.   Cell Stem Cell

BMP and Wnt Specify Hematopoietic Fate by Activation of the Cdx-Hox Pathway

(2008) Claudia Lengerke et al.   Cell Stem Cell

Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice

(2008) S. J. Gaunt et al.   DEVELOPMENT

Endocardial Brg1 Represses ADAMTS1 to Maintain the Microenvironment for Myocardial Morphogenesis

(2008) Kryn Stankunas et al.   DEVELOPMENTAL CELL

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE

Cdx gene deficiency compromises embryonic hematopoiesis in the mouse

(2008) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA