Article
Chemistry, Applied
Nathalie Almeida Lopes, Omar Mertins, Cristian Mauricio Barreto Pinilla, Adriano Brandelli
Summary: Liposomes modified with biomolecules demonstrate improved stability and specific structural characteristics, making them a profitable alternative to traditional liposomes. The presence of nisin promotes the transition of liposome structures from lamellar to cubic phase, with the association to polysaccharides not interfering with cubic phase formation. Different symmetries in the cubic phases are produced based on composition, preparation method, and temperature variation.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Physical
Christopher J. Garvey, Saffron J. Bryant, Aaron Elbourne, Taavi Hunt, Ben Kent, Martin Kreuzer, Markus Strobl, Roland Steitz, Gary Bryant
Summary: The maintenance of plasma membrane structure is crucial for cell viability. However, the macroscopic phase separation observed during dehydration and freezing can lead to cell death. Previous studies have shown that POPC can function as a line-active component in lipid vesicles, inhibiting macroscopic phase separation and stabilizing membrane microdomains. However, our research found that under reduced hydration, POPC cannot stabilize microdomains in various model membrane systems.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Pharmacology & Pharmacy
Antonio Lipa-Castro, Francois-Xavier Legrand, Gillian Barratt
Summary: Cochleate systems formed from phospholipids have useful sustained release capabilities, improving bioavailability and reducing toxicity. There are various methods available for preparing cochleates, as well as techniques for characterization, ranging from simple to more sophisticated ones. These features of cochleate systems can guide formulators in choosing suitable methods for their needs in terms of time, precision, and technological difficulty.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Polymer Science
Jia-Yao Wang, Yong-Jin Li, Ji-Chun You, Feng-Gang Bian
Summary: In this study, the phase segregation and localization of PBSU in a blend with PVDF were investigated using SAXS and DSC. It was found that the localization of PBSU in the interlamellar/interfibrillar regions of the pre-formed PVDF crystal framework gives rise to the double peaks observed in DSC and SAXS measurements.
CHINESE JOURNAL OF POLYMER SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Lukas Gajdos, V. Trevor Forsyth, Matthew P. Blakeley, Michael Haertlein, Anne Imberty, Eric Samain, Juliette M. Devos
Summary: L-Fucose and its derivatives are important in various biological processes, with applications in cancer research, glyco-immunology, and host-pathogen interactions. The production of perdeuterated L-fucose using glyco-engineered Escherichia coli has been described, with potential applications in structural biology techniques such as NMR and neutron crystallography. This perdeuterated fucose could be particularly useful in identifying detailed interactions with protein receptors in neutron macromolecular crystallography.
Article
Polymer Science
Kun Song, Dong Liu, Lin-Feng Wu, Zhe Wang
Summary: The growth of lamellar crystals in stretched crosslinked high-density polyethylene samples was investigated using in situ small-angle X-ray scattering and wide-angle X-ray diffraction. The growth process was found to undergo three stages: interface-controlled, diffusion-controlled, and crystal perfection stages through the Ostwald ripening mechanism. The transitions between stages were affected by chain diffusion, chain consumption, and depletion of crystallizable chains.
Article
Chemistry, Multidisciplinary
Gregory N. Smith, Sylvain Prevost
Summary: Small-angle neutron scattering (SANS) can be used to determine the distribution of molecules in mixtures of hydrogenous and deuterated species, with successful applications in polymer science. SANS measurements on combinations of n-tetradecane show good agreement between experiment and theory.
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2021)
Article
Polymer Science
Taotao Lin, Yongjin Li, Jiayao Wang, Jichun You
Summary: In this study, the exclusion behaviors of amorphous PMMA with different molecular weights during PVDF crystallization were investigated, showing that the molecular weight of the amorphous component has a significant impact on the diffusion coefficient and crystal growth rate of the crystalline component. As the molecular weight of PMMA increases, the exclusion behaviors become more pronounced, leading to larger pores in the extracted structure.
Article
Chemistry, Physical
Soren Grosskopf, Peter Fouquet, Lars Wiehemeier, Thomas Hellweg
Summary: The study investigates the influence of block copolymer architecture on bending elasticity of polymer-rich lamellar phases. The bending modulus kappa and bulk compression modulus (B) over bar values are determined within specific size ranges of EO and PO blocks.
Review
Biochemistry & Molecular Biology
Maksym Golub, Jorg Pieper
Summary: Small-angle neutron and X-ray scattering techniques provide structural insights of biomolecules in solution. Recent advancements include the establishment of direct connection between scattering data and high-resolution structures, the use of selective deuteration, symbiosis with molecular dynamics simulations, and integration with functional studies. Time-resolved experiments enable real-time monitoring of structural transformations of proteins.
Article
Biochemistry & Molecular Biology
Augusta de Santis, Ernesto Scoppola, Maria Francesca Ottaviani, Alexandros Koutsioubas, Lester C. Barnsley, Luigi Paduano, Gerardino D'Errico, Irene Russo Krauss
Summary: The structural properties of cholesterol-containing lipid bilayers with increasing amounts of polyunsaturated omega-3 lipids were investigated using multiple techniques in this study. Results indicate that the different effects of hybrid and symmetric omega-3 phospholipids on lipid bilayers' microscopic organization, with cholesterol able to suppress non-lamellar structures induced by symmetric polyunsaturated lipids. The structural organization of the resulting bilayer does not fit neatly into typical liquid ordered or liquid disordered phases, showing loose packing of lipid chain segments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Physics, Applied
V. K. Sharma, E. Mamontov
Summary: The effect of lithium chloride addition on the diffusivity and motion of lipids in DMPC vesicles was investigated. The results showed that lithium chloride increased the thermodynamic stability of the ordered phase and decreased the lateral and localized diffusion coefficients of lipids. This effect was attributed to the strong interaction between Li+ ions and the head group of DMPC lipid.
JOURNAL OF APPLIED PHYSICS
(2022)
Article
Polymer Science
Aristeidis Papagiannopoulos, Natassa Pippa, Costas Demetzos, Stergios Pispas, Aurel Radulescu
Summary: The study demonstrates that amphiphilic block copolymers can be effectively used to prepare mixed lipid-block copolymer vesicles with controlled lamellarity and significant potential for drug delivery.
Article
Cell Biology
Angelina Angelova, Borislav Angelov, Markus Drechsler, Thomas Bizien, Yulia E. Gorshkova, Yuru Deng
Summary: The study explores the self-assembly of long-chain PUFA plasmalogens with other lipid mixtures to form nanostructures, providing new insights for the development of nanomedicines for certain diseases.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Polymer Science
Magdalena Witek, Maciej Krzystyniak, Giovanni Romanelli, Teresa Witczak
Summary: This study utilizes a combination of experimental techniques to investigate the glass transition of dry rice pasta, revealing its nearly completely amorphous nature, with the glass transition occurring between 40 and 60 degrees Celsius. Changes in the secondary structure of starch within the pasta, along with partial loss of long-range order provided by the polymer structure, are also observed during the transition.
Article
Chemistry, Physical
Saffron J. Bryant, Andrew J. Christofferson, Tamar L. Greaves, Christopher F. McConville, Gary Bryant, Aaron Elbourne
Summary: Deep eutectic solvents (DESs) are a tailorable class of solvents that are distinct from conventional solvents. They possess unique bulk liquid and interfacial nanostructures, and their physicochemical properties are dictated by structure-property relationships. However, there is still a significant gap in our understanding of the underlying factors that govern their solvent properties.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Nicolo Paracini, Philipp Gutfreund, Rebecca Welbourn, Juan Francisco Gonzalez-Martinez, Kexin Zhu, Yansong Miao, Nageshwar Yepuri, Tamim A. . Darwish, Christopher Garvey, Sarah Waldie, Johan Larsson, Max Wolff, Marite Cardenas
Summary: Arrays of nanoparticle-supported lipid bilayers (nanoSLB) are lipid-coated nanopatterned interfaces that provide a platform to study curved model biological membranes using surface-sensitive techniques. We investigated the structure of lipid bilayers formed on nanoparticle arrays through vesicle fusion using scattering techniques and direct imaging. The presence of both flat and curved supported lipid bilayers on the same substrate, combined with the accuracy of grazing incidence neutron scattering, offers a promising approach to studying curvature-dependent membrane phenomena.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Christopher J. Garvey, Saffron J. Bryant, Aaron Elbourne, Taavi Hunt, Ben Kent, Martin Kreuzer, Markus Strobl, Roland Steitz, Gary Bryant
Summary: The maintenance of plasma membrane structure is crucial for cell viability. However, the macroscopic phase separation observed during dehydration and freezing can lead to cell death. Previous studies have shown that POPC can function as a line-active component in lipid vesicles, inhibiting macroscopic phase separation and stabilizing membrane microdomains. However, our research found that under reduced hydration, POPC cannot stabilize microdomains in various model membrane systems.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Aaron Elbourne, Madeleine Dupont, Rashad Kariuki, Nastaran Meftahi, Torben Daeneke, Tamar L. Greaves, Christopher F. McConville, Gary Bryant, Saffron J. Bryant, Quinn A. Besford, Andrew J. Christofferson
Summary: Ionic liquids (ILs) are extensively studied solvents with desirable properties for scientific and industrial applications. The IL-solid interface is a complex entity that has undergone evolving understanding, from a simple 1D double layer to a 3D ordered liquid interface. This study presents a holistic examination of the protic IL-solid interface, revealing a more complex nanostructure than previously reported and enhancing the overall understanding of IL interfacial solvation.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Engineering, Biomedical
Denver P. Linklater, Xavier Le Guevel, Erim Kosyer, Sergey Rubanov, Gary Bryant, Eric Hanssen, Vladimir A. Baulin, Eva Pereiro, Palalle G. Tharushi Perera, Jason V. Wandiyanto, Ana Angulo, Saulius Juodkazis, Elena P. Ivanova
Summary: Ultrasmall gold nanoclusters (AuNC) have unique optical and physicochemical properties, making them suitable for theranostic applications. However, their high diffusion across cellular barriers raises nanotoxicology concerns. This study investigates the toxicity of surface-modified 2 nm AuNCs on COS-7 fibroblast-like cells and reveals insights into their metabolism. The results show that AuNC-ZwBuEt is cytotoxic towards COS-7 cells and can cross the nuclear membrane, while AuNC-MHA is not cytotoxic. Endosomal escape and translocation of AuNC-ZwBuEt may be the cause of cytotoxicity, highlighting the need for further investigation of metal nanocluster-cell interactions.
ADVANCED NANOBIOMED RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Michael Wilms, Lesly V. Melendez, Rohan J. Hudson, Christopher R. Hall, Samantha Prabath Ratnayake, Trevor Smith, Enrico Della Gaspera, Gary Bryant, Timothy U. Connell, Daniel E. Gomez
Summary: We introduce a novel composite material composed of silver nanoparticles and three-dimensional molecular organic cages based on light-absorbing porphyrins. The porphyrin cages not only stabilize the particles but also enable diffusion and trapping of small molecules near the metallic surface. The combination of these two photoactive components leads to a Fano-resonant interaction, resulting in increased energy transfer and enhanced photocurrent for water-splitting applications. This composite structure demonstrates the potential of advanced photosensitizer systems with intrinsic porosity for photocatalytic and sensing applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Samir Eldemrdash, Giannis Thalassinos, Amani Alzahrani, Qiang Sun, Ella Walsh, Erin Grant, Hiroshi Abe, Tamar L. Greaves, Takeshi Ohshima, Petr Cigler, Pavel Matejicek, David A. Simpson, Andrew D. Greentree, Gary Bryant, Brant C. Gibson, Philipp Reineck
Summary: Fluorescent nanodiamonds containing nitrogen-vacancy centers have various applications in science and technology. The shape of nanodiamonds affects their properties and limits sensor applications. Using atomic force microscopy and scattering techniques, researchers found that nanodiamonds made from high-pressure high-temperature diamond have a disk-like shape with a high aspect ratio. This shape is important for quantum sensing measurements.
Article
Polymer Science
Jordan T. Lovegrove, Ben A. Humphreys, Chin Ken Wong, Liliana de Campo, Anna Wang, Christopher J. Garvey, Martina H. Stenzel
Summary: This article investigates a synthetic pathway to produce biologically compatible, crosslinked, multicompartment worms (MCWs) in aqueous solution by incorporating thermoresponsive poly-N-isopropylacrylamide (PNIPAM) to direct assembly above the lower critical solution temperature (LCST). The self-assembly process and mechanism of MCWs starting from primary micelles were observed and controlled by adjusting the temperature.
Article
Biochemistry & Molecular Biology
Shakil Ahmed Polash, Koen Garlick-Trease, Suneela Pyreddy, Selvakannan Periasamy, Gary Bryant, Ravi Shukla
Summary: Metal-organic frameworks (MOFs) are being developed as a promising tool for delivering biomolecules. In this study, a green fluorescence protein (GFP)-expressing plasmid DNA (pDNA) is encapsulated in a Zn-based MOF called a zeolitic imidazolate framework (ZIF), which is coated with positively charged amino acids (AA). The functionalized biocomposite shows enhanced uptake by prostate cancer cells and could be a potential non-viral gene delivery system.
Article
Polymer Science
Jordan Thomas Lovegrove, Radhika Raveendran, Patrick Spicer, Stephan Foerster, Christopher J. Garvey, Martina H. Stenzel
Summary: Margination refers to the movement of particles towards the endothelial wall within blood vessels. This study focused on 2D platelet particles as a potential drug delivery system and quantified their margination propensity. The results showed that 2D platelet particles exhibited increased margination compared to spherical particles, with higher margination observed at higher shear rates.
Article
Polymer Science
Dominik M. Schwaiger, Wiebke Lohstroh, Marcell Wolf, Christopher J. Garvey, Peter Mueller-Buschbaum
Summary: Blending PTB7 and PCBM films with binary solvent additive DIO:DPE accelerates the degradation of the films, but the removal of the additives at higher annealing temperature can restore the stability to the level of the pristine blend films, which is promising for photovoltaic applications.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Engineering, Environmental
Jingjing Mai, Christopher J. Garvey, Clement Matthew Chan, Steven Pratt, Bronwyn Laycock
Summary: Polyhydroxyalkanoates (PHAs) are attractive alternatives to petroleum-derived plastics, as they are derived from bacteria, thermoprocessible, and truly biodegradable. However, the common short chain length PHAs, such as poly(3-hydroxybutyrate) (P3HB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), are relatively stiff and brittle. This study demonstrates the synthesis and characterization of novel high molecular weight PHBV-b-PHBV-b-PHBV block copolymers, which show significantly improved mechanical properties compared to the starting materials. This approach offers an attractive platform for the production of biodegradable PHA materials for various applications.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Biomaterials
Saffron J. Bryant, Aaron Elbourne, Tamar L. Greaves, Gary Bryant
Summary: Deep eutectic solvents (DES) are customizable non-aqueous solvents with potential applications in various fields, including industrial dissolution and biomedicine. They have the ability to self-assemble amphiphilic molecules into liquid crystal phases, which can be utilized in drug delivery systems. This study investigated the self-assembly of a non-ionic lipid, phytantriol, in the DES choline chloride:urea with and without water. The results showed that the DES supported diverse phase behavior and the addition of water influenced the phase transition temperatures.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Materials Science, Multidisciplinary
Shakil Ahmed Polash, Suneela Pyreddy, Amanda N. Abraham, Sanje Mahasivam, Vipul Bansal, Linda Varadi, Gary Bryant, Ravi Shukla
Summary: Metal-organic frameworks (MOFs) are extensively studied for delivering therapeutic materials, including nucleic acids. The interaction between MOFs and serum proteins can change the biological properties of these therapeutic biocomposites. In this study, it is found that different crystal topologies of MOFs affect their interaction with serum albumin, with ZIF-8 showing stronger interaction. These findings have important implications for the design of MOF-based therapeutic agents.
MATERIALS ADVANCES
(2023)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)