Rationale and Design of the VITALITY-HFpEF Trial

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Efficacy and Safety of the Oral Soluble Guanylate Cyclase Stimulator

(2018) Paul W. Armstrong et al.   JACC-Heart Failure

Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas

(2018) Pooja Dewan et al.   EUROPEAN JOURNAL OF HEART FAILURE

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction

(2018) Barry A. Borlaug et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) study

(2017) Burkert Pieske et al.   EUROPEAN HEART JOURNAL

Patient-reported outcomes in the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED ejection fraction (SOCRATES-PRESERVED) study

(2017) Gerasimos Filippatos et al.   EUROPEAN JOURNAL OF HEART FAILURE

Association of Serial Kansas City Cardiomyopathy Questionnaire Assessments With Death and Hospitalization in Patients With Heart Failure With Preserved and Reduced Ejection Fraction

(2017) Yashashwi Pokharel et al.   JAMA Cardiology

Impact of Spironolactone on Longitudinal Changes in Health-Related Quality of Life in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist TrialCLINICAL PERSPECTIVE

(2016) Eldrin F. Lewis et al.   Circulation-Heart Failure

Exploring New Endpoints for Patients With Heart Failure With Preserved Ejection Fraction

(2016) Javed Butler et al.   Circulation-Heart Failure

Geographic variations in the PARADIGM-HF heart failure trial

(2016) Søren Lund Kristensen et al.   EUROPEAN HEART JOURNAL

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

(2016) Piotr Ponikowski et al.   EUROPEAN HEART JOURNAL

Quantifying clinical change: discrepancies between patients’ and providers’ perspectives

(2016) Rachel P. Dreyer et al.   QUALITY OF LIFE RESEARCH

Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction

(2016) Constantijn Franssen et al.   JACC-Heart Failure

Effects of sildenafil on invasive haemodynamics and exercise capacity in heart failure patients with preserved ejection fraction and pulmonary hypertension: a randomized controlled trial

(2015) Elke S. Hoendermis et al.   EUROPEAN HEART JOURNAL

Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction

(2015) Margaret M. Redfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparable Performance of the Kansas City Cardiomyopathy Questionnaire in Patients With Heart Failure With Preserved and Reduced Ejection Fraction

(2013) Susan M. Joseph et al.   Circulation-Heart Failure

Effect of Phosphodiesterase-5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure With Preserved Ejection Fraction

(2013) Margaret M. Redfield et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Multiple Testing in Group Sequential Trials Using Graphical Approaches

(2013) Willi Maurer et al.   Statistics in Biopharmaceutical Research

The cGMP Signaling Pathway as a Therapeutic Target in Heart Failure With Preserved Ejection Fraction

(2013) Stephen J. Greene et al.   Journal of the American Heart Association

Trends in Patients Hospitalized With Heart Failure and Preserved Left Ventricular Ejection Fraction

(2012) Benjamin A. Steinberg et al.   CIRCULATION

The effect of intravenous ferric carboxymaltose on health-related quality of life in patients with chronic heart failure and iron deficiency: a subanalysis of the FAIR-HF study

(2012) Josep Comin-Colet et al.   EUROPEAN HEART JOURNAL

Endothelial Dysfunction

(2012) Carolyn S.P. Lam et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiac Resynchronization and Quality of Life in Patients With Minimally Symptomatic Heart Failure

(2012) Peter J. Veazie et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

(2011) Johannes-Peter Stasch et al.   CIRCULATION

Heart rate reduction with ivabradine and health related quality of life in patients with chronic heart failure: results from the SHIFT study

(2011) Inger Ekman et al.   EUROPEAN HEART JOURNAL

Determining the non-inferiority margin for patient reported outcomes

(2011) Christoph Gerlinger et al.   PHARMACEUTICAL STATISTICS

Effects of Exercise Training on Health Status in Patients With Chronic Heart Failure

(2009) Kathryn E. Flynn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MMRM vs. LOCF: A Comprehensive Comparison Based on Simulation Study and 25 NDA Datasets

(2009) Ohidul Siddiqui et al.   Journal of Biopharmaceutical Statistics

Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics

(2009) Emily J. Tsai et al.   PHARMACOLOGY & THERAPEUTICS

General Multistage Gatekeeping Procedures

(2008) Alex Dmitrienko et al.   BIOMETRICAL JOURNAL