Article
Physiology
Fernando Vieira, Frank Silva Bezerra, Remi Coudroy, Annia Schreiber, Irene Telias, Sebastian Dubo, Giulia Cavalot, Sergio Martins Pereira, Thomas Piraino, Laurent Jean Brochard
Summary: High-flow nasal cannula (HFNC) generates positive airway pressure and reduces respiratory rate. These effects are more pronounced when the mouth is kept closed, leading to decreased respiratory workload. Increased resistance to breathing induces longer expiratory phase, which contributes to physiological benefits not observed with continuous positive airway pressure.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Medicine, Research & Experimental
Erin K. Reilly, Maurits S. Boon, Swar Vimawala, Chandala Chitguppi, Jena Patel, Kira Murphy, Karl Doghramji, Gurston G. Nyquist, Marc R. Rosen, Mindy R. Rabinowitz, Colin T. Huntley
Summary: The study found that restarting CPAP on the first postoperative day is well-tolerated for patients undergoing septoplasty/turbinectomy or functional endoscopic sinus surgery for OSA. Quality of life and CPAP outcomes improved or remained stable postoperatively, without significant complications.
Article
Pediatrics
Meryl Vedrenne-Cloquet, Sonia Khirani, Lucie Griffon, Charlotte Collignon, Sylvain Renolleau, Brigitte Fauroux
Summary: NIPPV is more effective than CPAP in reducing respiratory effort in infants with severe acute bronchiolitis. Both clinically and physiologically, NIPPV can significantly reduce respiratory effort and improve other indicators compared to CPAP.
PEDIATRIC PULMONOLOGY
(2023)
Article
Medicine, General & Internal
Elisa Ceriani, Annalisa Pitino, Dejan Radovanovic, Emanuele Salvi, Maddalena Matone, Thomas Teatini, Antonio Gidaro, Giovanni Tripepi, Pierachille Santus, Mercedes Gori, Chiara Cogliati
Summary: CPAP support can be a feasible therapeutic option for elderly patients with COVID-19, although its effectiveness is reduced in cases of severe respiratory impairment, high frailty, or delirium occurrence.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pediatrics
Arash Malakian, Mohammad Reza Aramesh, Mina Agahin, Masoud Dehdashtian
Summary: In this study, DUOPAP did not reduce the need for mechanical ventilation within the first 72 hours of birth compared to NCPAP. However, the duration of non-invasive ventilation, oxygen demand, need for multiple doses of surfactant, and length of stay in the DUOPAP group were less than those in the CPAP group.
Article
Medicine, General & Internal
Jae Hyuk Choi, Eunkyu Lee, Sang Duk Hong, Seung Kyu Chung, Yong Gi Jung, Hyo Yeol Kim
Summary: A retrospective analysis of OSA patients undergoing CPAP therapy showed significant improvements in laryngopharyngeal reflux symptoms and examination findings, independent of body mass index or OSA severity.CPAP treatment has the potential to reduce laryngeal reflux symptoms and improve laryngeal examination results in OSA patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Engineering, Biomedical
Fabio Savoldi, Lorenzo Svanetti, James K. H. Tsoi, Min Gu, Corrado Paganelli, Francesco Genna, Nicola F. Lopomo
Summary: The study found that the increase in applied force does not directly proportionally increase the contact pressure exerted by the CPAP mask on the face. While the overall average contact pressure increases with force, the contact areas do not show clear increments. The pressure exerted by a CPAP mask on the face of a subject may not be uniformly distributed.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Clinical Neurology
Alessandro Amaddeo, Diala Khraiche, Sonia Khirani, Mathilde Meot, Jean-Philippe Jais, Damien Bonnet, Brigitte Fauroux
Summary: The study found that severe SDB is uncommon in children with CHF, and CPAP may be beneficial by decreasing WOB and respiratory rate without deleterious effects on cardiac index.
Article
Nursing
Chestharid Borriboon, Jindarat Chaiard, Chiraporn Tachaudomdach, Sue Turale
Summary: This study aimed to investigate the relationship between health belief model factors and CPAP adherence in Thai individuals with obstructive sleep apnoea. Results showed a low rate of CPAP adherence, with perceived seriousness of the conditions being the only significant factor associated with adherence. Healthcare professionals, especially nurses, should provide support and education to encourage regular CPAP use and be aware of psychological factors affecting patients' perception of sleep apnoea and CPAP treatment. Intervention strategies targeting these factors should be developed and implemented in clinical practice.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Multidisciplinary Sciences
Narongkorn Saiphoklang, Kanyada Leelasittikul, Apiwat Pugongchai
Summary: Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea patients, and a predictive equation for CPAP in Thai patients was developed in this study, with neck circumference, body mass index, respiratory disturbance index, and lowest pulse oxygen saturation being significant factors in predicting the optimal pressure. The equation accounted for 50% of the variance in optimal pressure, providing insight into tailored CPAP therapy for Thai patients with OSA.
SCIENTIFIC REPORTS
(2021)
Article
Pediatrics
Qingxia Shi, Zhihua Zhao, Jilei Lin, Yin Zhang, Jihong Dai
Summary: A nomogram was established to predict the efficacy of CPAP on bronchiolitis, including ten predictive factors. The nomogram outperformed other scoring tools in terms of clinical benefits.
FRONTIERS IN PEDIATRICS
(2022)
Article
Clinical Neurology
Yoko Fujino, Yasunori Oka, Tomoko Wakamura
Summary: This study found that seasonal differences can impact the CPAP adherence of patients with obstructive sleep apnea. Patients in the adherent group had lower CPAP use rate and shorter duration in summer, while the non-adherent group showed significant differences between winter and summer.
Article
Peripheral Vascular Disease
Luis E. Okamoto, Jorge E. Celedonio, Emily C. Smith, Sachin Y. Paranjape, Bonnie K. Black, Amr Wahba, Jin-Woo Park, Cyndya A. Shibao, Andre Diedrich, Italo Biaggioni
Summary: We conducted two studies and found that continuous positive airway pressure (CPAP) can effectively reduce nocturnal supine hypertension in patients with autonomic failure, improve nocturia and symptoms of daytime orthostatic hypotension.
Article
Oncology
Jaehyeon Park, Ji Woon Yea, Se An Oh, Jongmoo Park, Jae Won Park, Jeong Eun Lee
Summary: This study aimed to determine the optimal pressure of continuous positive airway pressure (CPAP) for radiotherapy (RT) by observing changes in dosimetric parameters and lung volume according to pressure. The results showed that CPAP linearly increased lung volume and decreased dosimetric parameters within the pressure range of 7 to 13 cmH(2)O. Above 13 cmH(2)O, dosimetric parameters of the heart also significantly decreased.
Article
Medicine, General & Internal
Laetitia S. Gaspar, Janina Hesse, Muge Yalcin, Barbara Santos, Catarina Carvalhas-Almeida, Mafalda Ferreira, Joaquim Moita, Angela Relogio, Claudia Cavadas, Ana Rita Alvaro
Summary: The study revealed that obstructive sleep apnea (OSA) affects the biological clock, and long-term continuous positive airway pressure (CPAP) treatment can partially restore normal clock function. However, the treatment does not fully reverse the impact on clock gene expression levels.
Article
Respiratory System
Miguel A. Martinez-Garcia, Manuel Sanchez-de-la-Torre, David P. White, Ali Azarbarzin
Summary: Conventional measures of OSA severity, such as AHI and ODI, have limitations in capturing the severity of OSA and its physiological consequences. The sleep apnea-specific hypoxic burden (HB), which measures the sum of individual areas under the oxygen desaturation curve, shows promise in identifying high-risk individuals with OSA. HB captures the depth and duration of OSA-related hypoxemia, providing important disease characterizing features not captured by conventional metrics.
ARCHIVOS DE BRONCONEUMOLOGIA
(2023)
Review
Allergy
Wei-jie Guan, Grace Oscullo, Meng-zhang He, Dan-yuan Xu, Jose Daniel Gomez-Olivas, Miguel Angel Martinez-Garcia
Summary: Bronchiectasis is a complex and heterogeneous disease with various causes. It is characterized by neutrophilic inflammation but can also involve eosinophilic inflammation. Eosinophilic diseases, such as asthma and allergic bronchopulmonary aspergillosis, may coexist with bronchiectasis. Additionally, some bronchiectasis patients exhibit eosinophilia without identified concomitant diseases, and the role of eosinophils in this condition is not fully understood.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Letter
Critical Care Medicine
Martino F. Pengo, Grace Oscullo, Jose Daniel Gomez-Olivas, Grzegorz Bilo, Gianfranco Parati, Miguel Angel Martinez-Garcia
Article
Critical Care Medicine
Miguel Angel Martinez-Garcia, Raul Mendez, Casilda Olveira, Rosa Giron, Marta Garcia-Clemente, Luis Maiz, Oriol Sibila, Rafael Golpe, Juan Luis Rodriguez-Hermosa, Esther Barreiro, Concepcion Prados, Juan Rodriguez-Lopez, Grace Oscullo, Gonzalo Labarca, David de la Rosa
Summary: This study found a significant U-shaped relationship between BEC and severity and exacerbations in bronchiectasis, which was more prominent in the eosinopenic group. IC treatment only decreased the number and severity of exacerbations in the eosinophilic group.
Review
Medicine, General & Internal
David de la Rosa-Carrillo, Guillermo Suarez-Cuartin, Oriol Sibila, Rafael Golpe, Rosa-Maria Giron, Miguel-angel Martinez-Garcia
Summary: The use of inhaled antibiotics has expanded beyond cystic fibrosis patients to include non-CF bronchiectasis or chronic obstructive pulmonary disease patients. Inhaled antibiotics provide high concentrations at the site of infection, enhancing their effectiveness and allowing for long-term administration. New formulations of inhaled dry powder antibiotics offer advantages such as faster preparation and administration, as well as eliminating the need for cleaning nebulization equipment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Editorial Material
Medicine, General & Internal
Miguel Angel Martinez-Garcia
JOURNAL OF CLINICAL MEDICINE
(2023)
Editorial Material
Respiratory System
M. Miravitlles, M. A. Martinez-Garcia
Letter
Critical Care Medicine
Miguel Angel Martinez-Garcia, Alvar Agusti
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Editorial Material
Allergy
Grace Oscullo, Jose Daniel Gomez-Olivas, Miguel Angel Martinez-Garcia
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2023)
Editorial Material
Clinical Neurology
Grace Oscullo, Jose Daniel Gomez-Olivas, Miguel Angel Martinez-Garcia
SLEEP AND BREATHING
(2023)
Editorial Material
Clinical Neurology
Grace Oscullo, Jose Daniel Gomez-Olivas, Miguel Angel Martinez-Garcia
Editorial Material
Medicine, General & Internal
Jose Daniel Gomez-Olivas, Grace Oscullo, Miguel Angel Martinez-Garcia
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Jose Daniel Gomez-Olivas, Grace Oscullo, Miguel angel Martinez-Garcia
Summary: Bronchiectasis is a chronic inflammatory disease of the airway caused by various pulmonary and extra-pulmonary diseases. The etiology of bronchiectasis shows significant heterogeneity, with post-infectious and idiopathic bronchiectasis being the most common causes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Grace Oscullo, Jose Daniel Gomez-Olivas, Marina Ingles, Sergio Mompean, Rosalia Martinez-Perez, Guillermo Suarez-Cuartin, David la Rosa-Carrillo, Miguel Angel Martinez-Garcia
Summary: This study assessed the effects of inhaled corticosteroids (ICs) on patients with bronchiectasis-chronic obstructive pulmonary disease overlap syndrome (BCOS) and found that treatment with ICs reduced the frequency and severity of exacerbations without negative impact on other infectious outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Ramon Farre, Isaac Almendros, Miguel-Angel Martinez-Garcia, David Gozal
Summary: This review focuses on the experimental models used to study the consequences of sleep apnea (SA), including cell culture systems, animal models, and human SA models. The advantages, limitations, and relevant findings of these models are discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
