Mirror‐Image Oligonucleotides: History and Emerging Applications

L-DNA linear duplex: An efficient drug delivery carrier with a simple structure

(2019) A-Young Lee et al.   JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY

Mirror-image aptamer kissing complex for arginine-vasopressin sensing

(2018) Benoit Chovelon et al.   ANALYTICA CHIMICA ACTA

Streptavidin-mirror DNA tetrahedron hybrid as a platform for intracellular and tumor delivery of enzymes

(2018) Kyoung-Ran Kim et al.   JOURNAL OF CONTROLLED RELEASE

Acute hepatotoxicity of 2′ fluoro-modified 5–10–5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins

(2018) Wen Shen et al.   NUCLEIC ACIDS RESEARCH

Synthesis of l-Deoxyribonucleosides from d-Ribose

(2018) Wei-Syun Song et al.   JOURNAL OF ORGANIC CHEMISTRY

Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals

(2017) Chad R. Simmons et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterochiral DNA Strand-Displacement Circuits

(2017) Adam M. Kabza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The chemical evolution of oligonucleotide therapies of clinical utility

(2017) Anastasia Khvorova et al.   NATURE BIOTECHNOLOGY

A thermostable d-polymerase for mirror-image PCR

(2017) Andreas Pech et al.   NUCLEIC ACIDS RESEARCH

DNA nanotechnology

(2017) Nadrian C. Seeman et al.   Nature Reviews Materials

Mirror-image polymerase chain reaction

(2017) Wenjun Jiang et al.   Cell Discovery

Noncompetitive affinity assays of glucagon and amylin using mirror-image aptamers as affinity probes

(2016) Lian Yi et al.   ANALYST

Biostable L-DNAzyme for Sensing of Metal Ions in Biological Systems

(2016) Liang Cui et al.   ANALYTICAL CHEMISTRY

Adaptive PCR Based on Hybridization Sensing of Mirror-Image l-DNA

(2016) Nicholas M. Adams et al.   ANALYTICAL CHEMISTRY

Designing a biostable L-DNAzyme for lead(ii) ion detection in practical samples

(2016) Hao Liang et al.   Analytical Methods

Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs

(2016) Kyoung-Ran Kim et al.   JOURNAL OF CONTROLLED RELEASE

A synthetic molecular system capable of mirror-image genetic replication and transcription

(2016) Zimou Wang et al.   Nature Chemistry

An L-RNA Aptamer that Binds and Inhibits RNase

(2015) Charles Olea et al.   CHEMISTRY & BIOLOGY

Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics

(2015) Axel Vater et al.   DRUG DISCOVERY TODAY

Oligonucleotide Therapies: The Past and the Present

(2015) Karin E. Lundin et al.   HUMAN GENE THERAPY

Specific Inhibition of MicroRNA Processing Using l-RNA Aptamers

(2015) Jonathan T. Sczepanski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Throughput Enantiopurity Analysis Using Enantiomeric DNA-Based Sensors

(2015) Trevor A. Feagin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computing in mammalian cells with nucleic acid strand exchange

(2015) Benjamin Groves et al.   Nature Nanotechnology

Stereospecificity of Oligonucleotide Interactions Revisited: No Evidence for Heterochiral Hybridization and Ribozyme/DNAzyme Activity

(2015) Kai Hoehlig et al.   PLoS One

A cross-chiral RNA polymerase ribozyme

(2014) Jonathan T. Sczepanski et al.   NATURE

Utilizing the bioorthogonal base-pairing system ofl-DNA to design ideal DNA nanocarriers for enhanced delivery of nucleic acid cargos

(2014) Kyoung-Ran Kim et al.   Chemical Science

Binding of a Structured d-RNA Molecule by an l-RNA Aptamer

(2013) Jonathan T. Sczepanski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

l-DNA Molecular Beacon: A Safe, Stable, and Accurate Intracellular Nano-thermometer for Temperature Sensing in Living Cells

(2012) Guoliang Ke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals

(2012) Punit P Seth et al.   Molecular Therapy-Nucleic Acids

DNA Cage Delivery to Mammalian Cells

(2011) Anthony S. Walsh et al.   ACS Nano

Aptamers for allosteric regulation

(2011) Jan L Vinkenborg et al.   Nature Chemical Biology

Dynamic DNA nanotechnology using strand-displacement reactions

(2011) David Yu Zhang et al.   Nature Chemistry

An Aptamer Targeting the Apical-Loop Domain Modulates pri-miRNA Processing

(2010) Christina E. Lünse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mirror Image DNA Nanostructures for Chiral Supramolecular Assemblies

(2008) Chenxiang Lin et al.   NANO LETTERS

Synthesis and pharmaceutical application of l-ribose

(2008) Kazuya Okano   TETRAHEDRON