Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of Its Methionine-Rich Low-Complexity Domain

Published 2019 View Full Article

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Title
Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of Its Methionine-Rich Low-Complexity Domain
Authors
Keywords
Ataxin-2, TORC1, ROS, oxidative stress, neurodegeneration, aging, low-complexity sequence, phase separation, cross-β polymer, methionine
Journal
CELL
Volume 177, Issue 3, Pages 711-721.e8
Publisher
Elsevier BV
Online
2019-04-12
DOI
10.1016/j.cell.2019.02.044

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