Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

Published 2019 View Full Article

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Title
Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity
Authors
Keywords
obesity, MC4R, melanocortin, β-arrestin, UK Biobank, genetics, biased signaling, GPCRs
Journal
CELL
Volume 177, Issue 3, Pages 597-607.e9
Publisher
Elsevier BV
Online
2019-04-18
DOI
10.1016/j.cell.2019.03.044

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