Journal
CARDIOLOGY CLINICS
Volume 37, Issue 2, Pages 119-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccl.2019.01.001
Keywords
Atrial fibrillation; Heart failure; Epidemiology; Risk factors; Prognosis
Categories
Funding
- Velux Foundation
- NIH/NHLBI [2R01HL092577, 1R01HL128914]
- American Heart Association [18SFRN34110082, 17FTF33670369]
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The global prevalence of atrial fibrillation (AF) and heart failure (HF) is rising. Population-based studies have observed that AF and HF often coexist, predispose to each other, and share risk factors. Age is the most potent risk factor for both AF and HF, but race plays an important role. Although AF and HF share common risk factors, adjusting for these risk factors does not explain the higher risk of AF patients developing HF and vice versa. Common pathophysiologic mechanisms may explain this linkage. The morbidity and mortality outcomes with combined AF and HF are substantial and warrant improved preventive strategies.
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