Metabolic control and sex: A focus on inflammatory‐linked mediators

17β-Estradiol Directly Lowers Mitochondrial Membrane Microviscosity and Improves Bioenergetic Function in Skeletal Muscle

(2018) Maria J. Torres et al.   Cell Metabolism

Ectopic lipid deposition is associated with insulin resistance in postmenopausal women

(2018) Julie Abildgaard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Anti-Inflammatory Therapy With Canakinumab for the Prevention and Management of Diabetes

(2018) Brendan M. Everett et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Female sex hormones are necessary for the metabolic effects mediated by loss of Interleukin 18 signaling

(2018) Birgitte Lindegaard et al.   Molecular Metabolism

Ovarian hormones in innate inflammation

(2017) Alexandra Stubelius et al.   IMMUNOBIOLOGY

Deletion of interleukin 1 receptor-associated kinase 1 (Irak1) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle

(2017) Xiao-Jian Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen Metabolism in Abdominal Subcutaneous and Visceral Adipose Tissue in Postmenopausal Women

(2017) Natalia Hetemäki et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Leptin in the interplay of inflammation, metabolism and immune system disorders

(2017) Vanessa Abella et al.   Nature Reviews Rheumatology

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

The levels of adipokines in relation to hormonal changes during the menstrual cycle in young, normal-weight women

(2017) Katarzyna Wyskida et al.   Endocrine Connections

Role of muscle IL-6 in gender-specific metabolism in mice

(2017) Amalia Molinero et al.   PLoS One

Sex Steroid Hormones Regulate Leptin Transcript Accumulation and Protein Secretion in 3T3-L1 Cells

(2017) Mónica Z. Jenks et al.   Scientific Reports

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome

(2016) Andrew J. Murphy et al.   Cell Metabolism

Sex and gender differences in HIV-1 infection

(2016) M. Griesbeck et al.   CLINICAL SCIENCE

The Multifaceted Roles of Adipose Tissue—Therapeutic Targets for Diabetes and Beyond: The 2015 Banting Lecture

(2016) Philipp E. Scherer   DIABETES

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus

(2016) Alexandra Kautzky-Willer et al.   ENDOCRINE REVIEWS

Region-specific effects of oestradiol on adipose-derived stem cell differentiation in post-menopausal women

(2016) Kimberly A. Cox-York et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Genetic and epigenetic factors underlying sex differences in the regulation of gene expression in the brain

(2016) Vikram S. Ratnu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance

(2016) Sezin Dagdeviren et al.   MOLECULAR AND CELLULAR BIOLOGY

Adiponectin, the past two decades

(2016) Zhao V. Wang et al.   Journal of Molecular Cell Biology

Gender differences in metabolic syndrome components among the Korean 66-year-old population with metabolic syndrome

(2016) Sangjin Lee et al.   BMC Geriatrics

Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity

(2015) Kanakadurga Singer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles of GPER in diabetes and atherosclerosis

(2015) Matthias Barton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice

(2015) Patricia Pazos et al.   Scientific Reports

Inflammatory Cytokines in General and Central Obesity and Modulating Effects of Physical Activity

(2015) Frank M. Schmidt et al.   PLoS One

Interleukin-6 deletion in mice driven by aP2-Cre-ERT2 prevents against high-fat diet-induced gain weight and adiposity in female mice

(2014) B. Navia et al.   Acta Physiologica

The role of sex hormones in induced-systemic inflammation in female albino rats

(2014) A. Hassouna et al.   ACTA PHYSIOLOGICA HUNGARICA

Muscle-specific interleukin-6 deletion influences body weight and body fat in a sex-dependent manner

(2014) Beatriz Ferrer et al.   BRAIN BEHAVIOR AND IMMUNITY

From cytokine to myokine: the emerging role of interleukin-6 in metabolic regulation

(2014) Martin Pal et al.   IMMUNOLOGY AND CELL BIOLOGY

The relationship between adiponectin, progesterone, and temperature across the menstrual cycle

(2014) N. Hall et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Interplay between the immune system and adipose tissue in obesity

(2014) Mark A Exley et al.   JOURNAL OF ENDOCRINOLOGY

Biology of upper-body and lower-body adipose tissue—link to whole-body phenotypes

(2014) Fredrik Karpe et al.   Nature Reviews Endocrinology

In Vitro Palmitate Treatment of Myotubes from Postmenopausal Women Leads to Ceramide Accumulation, Inflammation and Affected Insulin Signaling

(2014) Julie Abildgaard et al.   PLoS One

The Dual-Specificity Phosphatase 2 (DUSP2) Does Not Regulate Obesity-Associated Inflammation or Insulin Resistance in Mice

(2014) Graeme I. Lancaster et al.   PLoS One

Gender differences in adiponectin levels and body composition in older adults: Hallym aging study

(2014) Hong Ji Song et al.   BMC Geriatrics

Sex and gender influences on pharmacological response: an overview

(2014) Flavia Franconi et al.   Expert Review of Clinical Pharmacology

Menopause is associated with decreased whole body fat oxidation during exercise

(2013) J. Abildgaard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Association between interleukin 1β and interleukin 10 concentrations: a cross-sectional study in young adolescents in Taiwan

(2013) Jung-Su Chang et al.   BMC Pediatrics

Interleukin-18 null mutation increases weight and food intake and reduces energy expenditure and lipid substrate utilization in high-fat diet fed mice

(2013) Eric P. Zorrilla et al.   BRAIN BEHAVIOR AND IMMUNITY

Innate Immune Receptors: Key Regulators of Metabolic Disease Progression

(2013) Chengcheng Jin et al.   Cell Metabolism

Changes in central and peripheral inflammatory responses to lipopolysaccharide in ovariectomized female rats

(2013) Takeshi Iwasa et al.   CYTOKINE

Interleukin-18 Activates Skeletal Muscle AMPK and Reduces Weight Gain and Insulin Resistance in Mice

(2013) Birgitte Lindegaard et al.   DIABETES

Sex Differences in Insulin Resistance and Cardiovascular Disease Risk

(2013) Sun H. Kim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet

(2012) Rika Yonezawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms of Inflammatory Responses in Obese Adipose Tissue

(2012) Shengyi Sun et al.   Annual Review of Nutrition

Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior

(2012) Albert Quintana et al.   BRAIN BEHAVIOR AND IMMUNITY

Estrogen Treatment After Ovariectomy Protects Against Fatty Liver and May Improve Pathway-Selective Insulin Resistance

(2012) L. Zhu et al.   DIABETES

Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes

(2012) S. Liu et al.   DIABETOLOGIA

Adiponectin: mechanistic insights and clinical implications

(2012) A. T. Turer et al.   DIABETOLOGIA

A Comparison of Inflammatory and Oxidative Stress Markers in Adipose Tissue from Weight-Matched Obese Male and Female Mice

(2012) Karen J. Nickelson et al.   Experimental Diabetes Research

Adiponectin as an Independent Predictor of the Presence and Degree of Hepatic Steatosis in the Dallas Heart Study

(2012) Aslan T. Turer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Global Gender Disparities in Obesity: A Review

(2012) Rebecca Kanter et al.   Advances in Nutrition

Sex differences in human adipose tissues – the biology of pear shape

(2012) Kalypso Karastergiou et al.   Biology of Sex Differences

Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey

(2011) Pia Pajunen et al.   BMC PUBLIC HEALTH

Estrogen Receptors and the Metabolic Network

(2011) Rodrigo P.A. Barros et al.   Cell Metabolism

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

Oestrogen alters adipocyte biology and protects female mice from adipocyte inflammation and insulin resistance

(2011) R. E. Stubbins et al.   DIABETES OBESITY & METABOLISM

Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice

(2011) G. M. Kowalski et al.   DIABETOLOGIA

Estrogen modulates abdominal adiposity and protects female mice from obesity and impaired glucose tolerance

(2011) Renee E. Stubbins et al.   EUROPEAN JOURNAL OF NUTRITION

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Effects of high-fat diet on plasma lipids, adiposity, and inflammatory markers in ovariectomized C57BL/6 mice

(2011) Antonio Ludgero-Correia et al.   NUTRITION

Gender differences in coronary heart disease

(2011) A.H.E.M. Maas et al.   Netherlands Heart Journal

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

(2010) Rinke Stienstra et al.   Cell Metabolism

Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling

(2010) L. D. Hoeg et al.   DIABETES

Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance

(2010) V. B. Matthews et al.   DIABETOLOGIA

Gluteofemoral body fat as a determinant of metabolic health

(2010) K N Manolopoulos et al.   INTERNATIONAL JOURNAL OF OBESITY

Exercise training in ovariectomized rats stimulates estrogenic-like effects on expression of genes involved in lipid accumulation and subclinical inflammation in liver

(2010) Abdolnaser Pighon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice

(2010) Alexander Balhuizen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hormonal regulation of pro-inflammatory and lipid peroxidation processes in liver of old ovariectomized female rats

(2009) R. A. Kireev et al.   BIOGERONTOLOGY

Transgenic mice with astrocyte-targeted production of interleukin-6 are resistant to high-fat diet-induced increases in body weight and body fat

(2009) Juan Hidalgo et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle

(2009) E.-G. Hong et al.   DIABETES

Reduced Energy Expenditure and Increased Inflammation Are Early Events in the Development of Ovariectomy-Induced Obesity

(2009) Nicole H. Rogers et al.   ENDOCRINOLOGY

Gender differences in adiponectin and low-grade inflammation among individuals with normal glucose tolerance, prediabetes, and type 2 diabetes

(2009) Juha Saltevo et al.   Gender Medicine

Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling

(2009) Louise Høeg et al.   JOURNAL OF APPLIED PHYSIOLOGY

Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype

(2009) Koji Ohashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GENDER DIFFERENCE IN GRANULOCYTE DYNAMICS AND APOPTOSIS AND THE ROLE OF IL-18 DURING ENDOTOXIN-INDUCED SYSTEMIC INFLAMMATION

(2009) Michiko Aoyama et al.   SHOCK

Menopause and the Metabolic SyndromeThe Study of Women's Health Across the Nation

(2008) Imke Janssen   ARCHIVES OF INTERNAL MEDICINE

Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice

(2008) K. R. Coenen et al.   DIABETOLOGIA

Increased visceral fat and decreased energy expenditure during the menopausal transition

(2008) J C Lovejoy et al.   INTERNATIONAL JOURNAL OF OBESITY

Interleukin-10 is a protective factor against diet-induced insulin resistance in liver

(2008) Dennys E. Cintra et al.   JOURNAL OF HEPATOLOGY

Metabolic Actions of Estrogen Receptor Beta (ERβ) are Mediated by a Negative Cross-Talk with PPARγ

(2008) Anna Foryst-Ludwig et al.   PLoS Genetics