Network-based characterization of drug-protein interaction signatures with a space-efficient approach

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KCF-S: KEGG Chemical Function and Substructure for improved interpretability and prediction in chemical bioinformatics

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Systematic identification of proteins that elicit drug side effects

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DrugBank 4.0: shedding new light on drug metabolism

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Identification of chemogenomic features from drug-target interaction networks using interpretable classifiers

(2012) Y. Tabei et al.   BIOINFORMATICS

Relating drug-protein interaction network with drug side effects

(2012) S. Mizutani et al.   BIOINFORMATICS

Drug target prediction using adverse event report systems: a pharmacogenomic approach

(2012) M. Takarabe et al.   BIOINFORMATICS

Large-scale prediction and testing of drug activity on side-effect targets

(2012) Eugen Lounkine et al.   NATURE

Extracting Sets of Chemical Substructures and Protein Domains Governing Drug-Target Interactions

(2011) Yoshihiro Yamanishi et al.   Journal of Chemical Information and Modeling

An Algorithmic Framework for Predicting Side Effects of Drugs

(2011) Nir Atias et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Analysis of multiple compound-protein interactions reveals novel bioactive molecules

(2011) H. Yabuuchi et al.   Molecular Systems Biology

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

ChEMBL: a large-scale bioactivity database for drug discovery

(2011) A. Gaulton et al.   NUCLEIC ACIDS RESEARCH

Mining Significant Substructure Pairs for Interpreting Polypharmacology in Drug-Target Network

(2011) Ichigaku Takigawa et al.   PLoS One

Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework

(2010) Y. Yamanishi et al.   BIOINFORMATICS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Protein-ligand interaction prediction: an improved chemogenomics approach

(2008) Laurent Jacob et al.   BIOINFORMATICS

Prediction of drug-target interaction networks from the integration of chemical and genomic spaces

(2008) Y. Yamanishi et al.   BIOINFORMATICS

Drug Target Identification Using Side-Effect Similarity

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