Journal
BIOMEDICAL ENGINEERING-APPLICATIONS BASIS COMMUNICATIONS
Volume 31, Issue 3, Pages -Publisher
WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.4015/S1016237219500248
Keywords
Numerical simulation; Bifurcation geometry; Wall shear stress; Oxygen wall flux
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In this study, blood flow associated with oxygen transport in the human carotid bifurcation was investigated numerically to assess the effects of bifurcation geometry on distribution and magnitude of the wall shear stress (WSS) and Sherwood number (Sh: dimensionless oxygen wall flux) at the favourable site of atherosclerotic lesion. Three-dimensional average models of the rigid-walled carotid bifurcation were constructed to perform simulations of steady blood flow under the wall boundary condition of a constant oxygen tension. The results demonstrated that changes in the bifurcation angle significantly altered the distribution of both the WSS and the Sh, even though the pattern of the axial flow was not very sensitive to the change in bifurcation angle. Flow with large inertia bifurcated at the flow divider and created a flow recirculation zone with low WSS and Sh on the outer wall of the internal carotid artery (ICA) sinus, where atherosclerotic lesions tend to develop. A wider bifurcation angle made the area of low Sh in the ICA sinus smaller, but the level of Sh along the outer wall of the ICA sinus extremely low. Another finding was that low Sh was associated with high WSS at the region distal to the ICA sinus. The Sh distribution did not readjust as fast as the WSS in this region, as reflected by the different rates of recovery of the WSS and Sh, thus uncoupling the transport process of oxygen transport from WSS.
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