PIMT-Mediated Protein Repair: Mechanism and Implications

Differences in α-Crystallin isomerization reveal the activity of protein isoaspartyl methyltransferase (PIMT) in the nucleus and cortex of human lenses

(2018) Yana A. Lyon et al.   EXPERIMENTAL EYE RESEARCH

PCMT1 is an unfavorable predictor and functions as an oncogene in bladder cancer

(2018) Liming Dong et al.   IUBMB LIFE

New findings on SNP variants of human protein L-isoaspartyl methyltransferase that affect catalytic activity, thermal stability, and aggregation

(2018) Jeungjin Kim et al.   PLoS One

Polymorphic Variants of Human Protein l-Isoaspartyl Methyltransferase Affect Catalytic Activity, Aggregation, and Thermal Stability

(2017) Charity Juang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Automatic time-shift alignment method for chromatographic data analysis

(2017) Qing-Xia Zheng et al.   Scientific Reports

Protein-L-Isoaspartyl Methyltransferase (PIMT) Is Required for Survival of Salmonella Typhimurium at 42°C and Contributes to the Virulence in Poultry

(2017) Pavan K. Pesingi et al.   Frontiers in Microbiology

Development of Chemical Tools to Monitor and Control Isoaspartyl Peptide Methyltransferase Activity

(2016) Yusuke Kimura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

(p)ppGpp-Dependent Persisters Increase the Fitness of Escherichia coli Bacteria Deficient in Isoaspartyl Protein Repair

(2016) Kelsey E. VandenBerg et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Critical role of protein L-isoaspartyl methyltransferase in basic fibroblast growth factor-mediated neuronal cell differentiation

(2016) To Thi Mai Dung et al.   BMB Reports

Chaperone protein l-isoaspartate (d-aspartyl) O-methyltransferase as a novel predictor of poor prognosis in lung adenocarcinoma

(2016) Heisuke Saito et al.   HUMAN PATHOLOGY

Contribution of protein isoaspartate methyl transferase (PIMT) in the survival of Salmonella Typhimurium under oxidative stress and virulence

(2016) Manoj Kumawat et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The enzyme l-isoaspartyl (d-aspartyl) methyltransferase is required for VEGF-dependent endothelial cell migration and tubulogenesis

(2016) Amira Ouanouki et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Rice PROTEINl-ISOASPARTYL METHYLTRANSFERASE isoforms differentially accumulate during seed maturation to restrict deleterious isoAsp and reactive oxygen species accumulation and are implicated in seed vigor and longevity

(2016) Bhanu Prakash Petla et al.   NEW PHYTOLOGIST

Racemized and Isomerized Proteins in Aging Rat Teeth and Eye Lens

(2016) Rebeccah A. Warmack et al.   REJUVENATION RESEARCH

The d-isoAsp-25 variant of histone H2B is highly enriched in active chromatin: potential role in the regulation of gene expression?

(2015) Zhenxia Qin et al.   AMINO ACIDS

Crystal structure and activity of protein L-isoaspartyl-O-methyltransferase from Vibrio cholerae, and the effect of AdoHcy binding

(2015) Tanaya Chatterjee et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Prediction of binding modes between protein l-isoaspartyl (d-aspartyl) O-methyltransferase and peptide substrates including isomerized aspartic acid residues using in silico analytic methods for the substrate screening

(2015) Akifumi Oda et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells

(2015) D. Ouazia et al.   NEUROSCIENCE

Autophagy revisited: A conversation with Christian de Duve

(2014) Daniel J. Klionsky   Autophagy

iTRAQ Quantitative Clinical Proteomics Revealed Role of Na+K+-ATPase and Its Correlation with Deamidation in Vascular Dementia

(2014) Sunil S. Adav et al.   JOURNAL OF PROTEOME RESEARCH

Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse

(2014) Aleksandra Dimitrijevic et al.   PLoS One

An Arabidopsis ATP-Dependent, DEAD-Box RNA Helicase Loses Activity upon IsoAsp Formation but Is Restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE

(2013) N. R. Nayak et al.   PLANT CELL

PROTEIN L-ISOASPARTYL METHYLTRANSFERASE2 Is Differentially Expressed in Chickpea and Enhances Seed Vigor and Longevity by Reducing Abnormal Isoaspartyl Accumulation Predominantly in Seed Nuclear Proteins

(2013) P. Verma et al.   PLANT PHYSIOLOGY

Protein methylation at the surface and buried deep: thinking outside the histone box

(2013) Steven G. Clarke   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of Enzymatic Activity by Deamidation and Their Subsequent Repair by Protein l-isoaspartyl Methyl Transferase

(2012) Trina Dutta et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Fluorescence and Phosphorescence from Higher Excited States of Organic Molecules

(2012) Takao Itoh   CHEMICAL REVIEWS

Protein damage, repair and proteolysis

(2012) Niki Chondrogianni et al.   MOLECULAR ASPECTS OF MEDICINE

Considerations in the Identification of Endogenous Substrates for Protein L-Isoaspartyl Methyltransferase: The Case of Synuclein

(2012) Gareth J. Morrison et al.   PLoS One

Protein L-isoaspartyl methyltransferase regulates p53 activity

(2012) Jae-Cheol Lee et al.   Nature Communications

Protein Isoaspartate Methyltransferase-Mediated 18O-Labeling of Isoaspartic Acid for Mass Spectrometry Analysis

(2011) Min Liu et al.   ANALYTICAL CHEMISTRY

Chemical waste risk reduction and environmental impact generated by laboratory activities in research and teaching institutions

(2011) Elizabeth de Souza Nascimento et al.   Brazilian Journal of Pharmaceutical Sciences

Analysis of Isoaspartic Acid by Selective Proteolysis with Asp-N and Electron Transfer Dissociation Mass Spectrometry

(2010) Wenqin Ni et al.   ANALYTICAL CHEMISTRY

The Role of Protein L-Isoaspartyl / D-Aspartyl O-Methyltransferase (PIMT) in Intracellular Signal Transduction

(2010) Takemitsu Furuchi et al.   CHEMISTRY & BIODIVERSITY

Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides

(2010) Hongqian Yang et al.   ELECTROPHORESIS

Repair of Isoaspartate Formation Modulates the Interaction of Deamidated 4E-BP2 with mTORC1 in Brain

(2010) Michael Bidinosti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spontaneous degradation of polypeptides at aspartyl and asparaginyl residues: Effects of the solvent dielectric

(2010) Todd V. Brennan et al.   PROTEIN SCIENCE

Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans

(2009) Shilpi Khare et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The V119I polymorphism in protein L-isoaspartate O-methyltransferase alters the substrate-binding interface

(2009) Karen Rutherford et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Chemo-Enzymatic Detection of Protein Isoaspartate Using Protein Isoaspartate Methyltransferase and Hydrazine Trapping

(2008) Joshua F. Alfaro et al.   ANALYTICAL CHEMISTRY