In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

Trimethyltin-induced hippocampal neurodegeneration: A mechanism-based review

(2016) Sueun Lee et al.   BRAIN RESEARCH BULLETIN

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Arginine Deprivation and Immune Suppression in a Mouse Model of Alzheimer's Disease

(2015) Matthew J. Kan et al.   JOURNAL OF NEUROSCIENCE

Glucocorticoid sensitization of microglia in a genetic mouse model of obesity and diabetes

(2014) Aditi Dey et al.   JOURNAL OF NEUROIMMUNOLOGY

Specific Binding and Characteristics of 18β-Glycyrrhetinic Acid in Rat Brain

(2014) Kazushige Mizoguchi et al.   PLoS One

Insulin resistance, neuroinflammation, and Alzheimer’s disease

(2014) Dema Najem et al.   REVIEWS IN THE NEUROSCIENCES

Brain mineralocorticoid receptors in cognition and cardiovascular homeostasis

(2014) Elise P. Gomez-Sanchez   STEROIDS

Toxicity of Trimethyltin and Dimethyltin in Rats and Mice

(2013) Xiaojiang Tang et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Potent and multiple regulatory actions of microglial glucocorticoid receptors during CNS inflammation

(2013) M Á Carrillo-de Sauvage et al.   CELL DEATH AND DIFFERENTIATION

Medicinal Chemistry of Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1)

(2013) James S. Scott et al.   JOURNAL OF MEDICINAL CHEMISTRY

11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action

(2013) Karen Chapman et al.   PHYSIOLOGICAL REVIEWS

Neuroinflammatory basis of metabolic syndrome

(2013) Sudarshana Purkayastha et al.   Molecular Metabolism

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

(2012) Dimitrije Krstic et al.   Journal of Neuroinflammation

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

(2012) Boonrat Chantong et al.   Journal of Neuroinflammation

Altered Distribution of Juxtaparanodal Kv1.2 Subunits Mediates Peripheral Nerve Hyperexcitability in Type 2 Diabetes Mellitus

(2012) J. Zenker et al.   JOURNAL OF NEUROSCIENCE

Insulin-like growth factors in the brain and their potential clinical implications

(2012) E. E. Benarroch   NEUROLOGY

Indomethacin Ameliorates Trimethyltin-Induced Neuronal Damage in Vivo by Attenuating Oxidative Stress in the Dentate Gyrus of Mice

(2011) Nguyen Quynh Huong et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mechanisms of Glucocorticoids in the Control of Neuroinflammation

(2011) N. Schweingruber et al.   JOURNAL OF NEUROENDOCRINOLOGY

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases: An overview

(2011) Alex Odermatt et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Exposure to an organometal compound stimulates adipokine and cytokine expression in white adipose tissue

(2010) Palaniyandi Ravanan et al.   CYTOKINE

11β-Hydroxysteroid dehydrogenase type 1 inhibition in type 2 diabetes mellitus

(2010) G. Hollis et al.   DIABETES OBESITY & METABOLISM

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

(2010) Caitlin S. Wyrwoll et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Microglia express functional 11β-hydroxysteroid dehydrogenase type 1

(2010) Andres Gottfried-Blackmore et al.   GLIA

Contribution of in vitro neurotoxicology studies to the elucidation of neurodegenerative processes

(2009) M.G. Zurich et al.   BRAIN RESEARCH BULLETIN

Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling

(2009) Antero Salminen et al.   CELLULAR SIGNALLING

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Trimethyltin-evoked apoptosis of murine hippocampal granule neurons is accompanied by the expression of interleukin-1beta and interleukin-1 receptor antagonist in cells of ameboid phenotype, the majority of which are NG2-positive

(2008) Anna Fiedorowicz et al.   BRAIN RESEARCH BULLETIN

Insulin and Dexamethasone Dynamically Regulate Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1

(2008) Aran Balachandran et al.   ENDOCRINOLOGY

The As and Ds of stress: Metabolic, morphological and behavioral consequences

(2008) Lawrence P. Reagan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Altered expression of DJ-1 in the hippocampal cells following in vivo and in vitro neuronal damage induced by trimethyltin

(2008) Reiko Nagashima et al.   NEUROSCIENCE LETTERS

The type 1 interleukin 1 receptor is not required for the death of murine hippocampal dentate granule cells and microglia activation

(2007) G. Jean Harry et al.   BRAIN RESEARCH