Highly Enantioselective Synthesis of Fused Tri- and Tetrasubstituted Aziridines: aza-Darzens Reaction of Cyclic Imines with α-Halogenated Ketones Catalyzed by Bifunctional Phosphonium Salt

Catalytic asymmetric Darzens and aza-Darzens reactions for the synthesis of chiral epoxides and aziridines.

(2018) Jesus M. de los Santos et al.   ChemCatChem

Phosphine-Catalyzed Asymmetric Organic Reactions

(2018) Huanzhen Ni et al.   CHEMICAL REVIEWS

Direct Asymmetric Vinylogous Mannich Addition of 3,5-Disubstituted-4-nitroisoxazoles to Isatin-Derived Imines Catalyzed by a Bifunctional Phase-Transfer-Catalyst

(2018) Xuejian Xia et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Aziridination of N-Sulphonyl Ketimines with Unfunctionalized Ketones: A One-pot Approach to Multisubstituted Fused Aziridines

(2017) Sheng Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Amino Acid-Derived Bifunctional Phosphines for Enantioselective Transformations

(2016) Tianli Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry - Preparation and Synthetic Application of 1-Azoniabicyclo[n.1.0]alkanes

(2016) Jeroen Dolfen et al.   ADVANCED SYNTHESIS & CATALYSIS

Intramolecular Radical Aziridination of Allylic Sulfamoyl Azides by Cobalt(II)-Based Metalloradical Catalysis: Effective Construction of Strained Heterobicyclic Structures

(2016) Huiling Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral quaternary phosphonium salts as phase-transfer catalysts for environmentally benign asymmetric transformations

(2016) Shiyao Liu et al.   GREEN CHEMISTRY

Enantioselective Michael Addition of Malonates to Chalcone Derivatives Catalyzed by Dipeptide-derived Multifunctional Phosphonium Salts

(2016) Dongdong Cao et al.   JOURNAL OF ORGANIC CHEMISTRY

P(NMe2)3-Mediated Aziridination of Imines with α-Ketoesters for Synthesis of Aziridine-2-carboxylates

(2016) Jin Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Amide-Phosphonium Salt as Bifunctional Phase Transfer Catalyst for Asymmetric 1,6-Addition of Malonate Esters to para-Quinone Methides

(2016) Luo Ge et al.   JOURNAL OF ORGANIC CHEMISTRY

Diethyl Phosphite Initiated Coupling of α-Ketoesters with Imines for Synthesis of α-Phosphonyloxy-β-amino Acid Derivatives and Aziridine-2-carboxylates

(2016) Jin Jiang et al.   ORGANIC LETTERS

Synthesis of Chiral Spiro-Aziridine Oxindoles via Aza-Corey–Chaykovsky Reaction of Isatin Derived N-tert-Butanesulfinyl Ketimines

(2016) Saumen Hajra et al.   ORGANIC LETTERS

Enantioselective Alkylation of Glycine Imine Promoted by Amino-Acid-Derived Phosphonium Salts

(2016) Shan Wen et al.   Asian Journal of Organic Chemistry

Enantioselective synthesis of 3-fluoro-3-allyl-oxindoles via phosphine-catalyzed asymmetric γ-addition of 3-fluoro-oxindoles to 2,3-butadienoates

(2015) Tianli Wang et al.   CHEMICAL COMMUNICATIONS

Dipeptide-Derived Multifunctional Quaternary Phosphonium Salt Catalyzed Asymmetric Cyclizations via a Tandem Michael Addition/SN2 Sequence

(2015) Dongdong Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synergistic Catalysis of Ionic Brønsted Acid and Photosensitizer for a Redox Neutral Asymmetric α-Coupling of N-Arylaminomethanes with Aldimines

(2015) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives

(2015) Tianli Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrocatalytic Aziridination of Alkenes Mediated by n-Bu4NI: A Radical Pathway

(2015) Jie Chen et al.   ORGANIC LETTERS

Bifunctional Amino Sulfonohydrazide Catalyzed Direct Asymmetric Mannich Reaction of Cyclic Ketimines with Ketones: Highly Diastereo- and Enantioselective Construction of Quaternary Carbon Stereocenters

(2015) Sheng Zhang et al.   ORGANIC LETTERS

Highly enantioselective construction of tertiary thioethers and alcohols via phosphine-catalyzed asymmetric γ-addition reactions of 5H-thiazol-4-ones and 5H-oxazol-4-ones: scope and mechanistic understandings

(2015) Tianli Wang et al.   Chemical Science

Recent Developments in Asymmetric Aziridination

(2014) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of 3,3′-Diaryloxindoles as Triarylmethanes with a Chiral All-Carbon Quaternary Center: Phase-Transfer-Catalyzed SNAr Reaction

(2014) Seiji Shirakawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles

(2014) Tianli Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Epoxidation and Aziridination of Olefins and Their Synthetic Applications

(2014) Yingguang Zhu et al.   CHEMICAL REVIEWS

Recent Advances in the Stereoselective Synthesis of Aziridines

(2014) Leonardo Degennaro et al.   CHEMICAL REVIEWS

Synthesis and Reactivity of 2-(Carboxymethyl)aziridine Derivatives

(2014) Gert Callebaut et al.   CHEMICAL REVIEWS

Ruthenium Porphyrin Catalyzed Three-Component Reaction of Diazo Compounds, Nitrosoarenes, and Alkynes: An Efficient Approach to Multifunctionalized Aziridines

(2014) Annapureddy Rajasekar Reddy et al.   ORGANIC LETTERS

Asymmetric Synthesis of Trisubstituted Aziridines via Aza-Darzens Reaction of Chiral Sulfinimines

(2014) Toni Moragas et al.   ORGANIC LETTERS

Amino Acid-Derived Phosphonium Salts-Catalyzed Michael Addition of 3-Substituted Oxindoles

(2013) Xiaoyu Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Thiourea-phosphonium salts from amino acids: cooperative phase-transfer catalysts in the enantioselective aza-Henry reaction

(2013) Dongdong Cao et al.   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric Darzens Reactions

(2013) Peter Bako et al.   CURRENT ORGANIC SYNTHESIS

Efficient approach for the design of effective chiral quaternary phosphonium salts in asymmetric conjugate additions

(2013) Seiji Shirakawa et al.   Chemical Science

Double Stereodifferentiation in the Catalytic Asymmetric Aziridination of Imines Prepared from α-Chiral Amines

(2012) Li Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbonate, acetate and phenolate phosphonium salts as catalysts in transesterification reactions for the synthesis of non-symmetric dialkyl carbonates

(2012) Maurizio Selva et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Base-Free Electrophilic Amination of Benzofuran-2(3H)-ones: Catalysis by Binol-Derived P-Spiro Quaternary Phosphonium Salts

(2011) Chuan-Le Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Regioselectivity in the ring opening of non-activated aziridines

(2011) Sonja Stanković et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Asymmetric Synthesis of Trisubstituted Aziridines

(2011) Li Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Brønsted Acid-Catalyzed Asymmetric Trisubstituted Aziridine Synthesis Using α-Diazoacyl Oxazolidinones

(2011) Takuya Hashimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Aza-Darzens Reaction with a Vaulted Biphenanthrol Magnesium Phosphate Salt

(2011) Shawn E. Larson et al.   ORGANIC LETTERS

Highly enantioselective asymmetric Darzens reactions with a phase transfer catalyst

(2011) Yan Liu et al.   Chemical Science

Controlled Diastereo- and Enantioselection in a Catalytic Asymmetric Aziridination

(2010) Aman A. Desai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphonium Salt Organocatalysis

(2009) Thomas Werner   ADVANCED SYNTHESIS & CATALYSIS

Phosphonium Salts as Chiral Phase-Transfer Catalysts: Asymmetric Michael and Mannich Reactions of 3-Aryloxindoles

(2009) Rongjun He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cinchona-based phase-transfer catalysts for asymmetric synthesis

(2009) Sang-sup Jew et al.   CHEMICAL COMMUNICATIONS

Aziridine alkaloids as potential therapeutic agents

(2009) Fyaz M.D. Ismail et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Aziridine Synthesis via Nucleophilic Attack of Carbene Equivalents on Imines: the Aza-Darzens Reaction

(2009) Joseph Sweeney   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Chiral Arylaminophosphonium Barfates as a New Class of Charged Brønsted Acid for the Enantioselective Activation of Nonionic Lewis Bases

(2009) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of Chiral Phosphonium Dialkyl Phosphite as a Highly ReactiveP-Nucleophile: Application to Asymmetric Hydrophosphonylation of Aldehydes

(2009) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evidence for a Boroxinate Based Brønsted Acid Derivative of VAPOL as the Active Catalyst in the Catalytic Asymmetric Aziridination Reaction

(2009) Gang Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Aza-Darzens Reaction Catalyzed by A Chiral Phosphoric Acid

(2009) Takahiko Akiyama et al.   ORGANIC LETTERS

Highly Efficient AsymmetricTrans-Selective Aziridination of Diazoacetamides andN-Boc-imines Catalyzed by Chiral Brønsted Acids

(2009) Xiaofei Zeng et al.   ORGANIC LETTERS

Recent developments in asymmetric aziridination

(2009) Hélène Pellissier   TETRAHEDRON

Binaphthyl-Modified Quaternary Phosphonium Salts as Chiral Phase-Transfer Catalysts: Asymmetric Amination of β-Keto Esters

(2008) Rongjun He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Directed Asymmetric Quaternization of a Peptide Backbone at a C-Terminal Azlactone

(2008) Daisuke Uraguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Tetraaminophosphonium Carboxylate-Catalyzed Direct Mannich-Type Reaction

(2008) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trans-Selective Asymmetric Aziridination of Diazoacetamides andN-Boc Imines Catalyzed by Axially Chiral Dicarboxylic Acid

(2008) Takuya Hashimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY