Catalytic Asymmetric (4+3) Cyclizations of In Situ Generated ortho -Quinone Methides with 2-Indolylmethanols

Catalytic Asymmetric [2+3] Cyclizations of Azlactones with Azonaphthalenes

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereo- and Enantioselective Synthesis of Cyclo-hepta[b]indoles via Chiral Phosphoric Acid-Catalyzed (4+3)-Cycloaddition

(2018) Coralie Gelis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A chiral scandium-complex-catalyzed asymmetric inverse-electron-demand oxa-Diels–Alder reaction of o-quinone methides with fulvenes

(2018) Jianlin Zhang et al.   CHEMICAL COMMUNICATIONS

Recent advances in the application of Diels–Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis

(2018) Baochao Yang et al.   CHEMICAL SOCIETY REVIEWS

Synergistic-Catalysis-Enabled Reaction of 2-Indolymethanols with Oxonium Ylides for the Construction of 3-Indolyl-3-Alkoxy Oxindole Frameworks

(2018) Chun Ma et al.   Chemistry-An Asian Journal

Cooperative Catalysis-Enabled Asymmetric α-Arylation of Aldehydes Using 2-Indolylmethanols as Arylation Reagents

(2018) Meng-Meng Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Spiro-oxindole-ε-lactones through N-Heterocyclic Carbene Catalysis

(2018) Qiang Liu et al.   ORGANIC LETTERS

Enantioselective Decarboxylative Alkylation of β-Keto Acids to ortho-Quinone Methides as Reactive Intermediates: Asymmetric Synthesis of 2,4-Diaryl-1-benzopyrans

(2018) Hyun Jung Jeong et al.   ORGANIC LETTERS

1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans

(2018) Lina Liu et al.   Organic Chemistry Frontiers

Regioselective [3+3] Cyclization of 2-Indolymethanols with Vinylcyclopropanes via Metal Catalysis

(2018) Zi-Qi Zhu et al.   ADVANCED SYNTHESIS & CATALYSIS

NHC-Catalyzed Enantioselective [4+3] Cycloaddition of Ortho -Hydroxyphenyl Substituted Para -Quinone Methides with Isatin-Derived Enals

(2018) Wenjun Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric [4+2] Cyclization of para -Quinone Methide Derivatives with 3-Alkyl-2-vinylindoles

(2018) Xiao-Li Jiang et al.   ADVANCED SYNTHESIS & CATALYSIS

Phosphoric Acid Catalyzed Aldehyde Addition to in Situ Generated o-Quinone Methides: An Enantio- and Diastereoselective Entry toward cis-3,4-Diaryl Dihydrocoumarins

(2018) Matthias Spanka et al.   ORGANIC LETTERS

Palladium-Catalyzed Enantioselective Addition of Chiral Metal Enolates to In Situ Generated ortho -Quinone Methides

(2018) Fabian Göricke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Free [4+3]-Cycloaddition of ortho -Quinone Methides and Isomünchnones: Catalytic and Diastereoselective Assembly of Oxa-bridged Oxazocine Scaffolds

(2018) Heather Lam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Catalytic Asymmetric Construction of Axially Chiral 3,3′-Bisindole Skeletons

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Catalyzed (4 + 3) Cyclization of Vinyl Aziridines with para-Quinone Methide Derivatives

(2018) Fei Jiang et al.   ACS Catalysis

Enantioselective Construction of Cyclopenta[b]indole Scaffolds via the Catalytic Asymmetric [3 + 2] Cycloaddition of 2-Indolylmethanols with p-Hydroxystyrenes

(2017) Meng-Meng Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Dihydrocoumarins through Chiral Phosphoric Acid-Catalyzed Cycloannulation of para-Quinone Methides and Azlactones

(2017) Zhi-Pei Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Indolylmethanols as Reactants in Catalytic Asymmetric Reactions

(2017) Guang-Jian Mei et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric synthesis of dihydrocoumarins via the organocatalytic hetero-Diels–Alder reaction of ortho-quinone methides

(2017) Lili Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective [4 + 2] Cycloaddition of o-Quinone Methides and Vinyl Sulfides: Indirect Access to Generally Substituted Chiral Chromanes

(2017) Zhaobin Wang et al.   ORGANIC LETTERS

Phosphine-Catalyzed Enantioselective [4 + 2] Annulation of o-Quinone Methides with Allene Ketones

(2017) Zhen Wang et al.   ORGANIC LETTERS

Relay Catalysis: Manganese(III) Phosphate Catalyzed Asymmetric Addition of β-Dicarbonyls to ortho-Quinone Methides Generated by Catalytic Aerobic Oxidation

(2017) Konrad Gebauer et al.   ORGANIC LETTERS

Enantioselective Direct α-Arylation of Pyrazol-5-ones with 2-Indolylmethanols via Organo-Metal Cooperative Catalysis

(2017) Zi-Qi Zhu et al.   ORGANIC LETTERS

Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and β-functionalized ketone

(2017) Lili Zhang et al.   RSC Advances

Copper(II)-Catalyzed Asymmetric 1,3-Dipolar [3+4] Cycloaddition and Kinetic Resolution of Azomethine Imines with Azoalkenes

(2016) Liang Wei et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric [3+2] Cycloadditions of C-3 Unsubstituted 2-Indolylmethanols: Regio-, Diastereo- and Enantioselective Construction of the Cyclopenta[b]indole Framework

(2016) Zi-Qi Zhu et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Domino Oxa-Michael/1,6-Addition Reactions: Asymmetric Synthesis of Chromans Bearing Oxindole Scaffolds

(2016) Kun Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Rhodium/Phosphoric Acid Catalysis for the Enantioselective Addition of Oxonium Ylides to ortho -Quinone Methides

(2016) Santosh Kumar Alamsetti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective and Regioselective [3+3] Cycloadditions Using 2-Indolylmethanols as 3 C Building Blocks

(2016) Xiao-Xue Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Brønsted Acid Catalyzed [3+2]-Cycloaddition of 2-Vinylindoles with In Situ Generated 2-Methide-2H-indoles: Highly Enantioselective Synthesis of Pyrrolo[1,2-a]indoles

(2016) Kalisankar Bera et al.   CHEMISTRY-A EUROPEAN JOURNAL

Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis

(2016) Ashley A. Jaworski et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Retro-Claisen Reaction by Chiral Primary Amine Catalysis

(2016) Yunbo Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted Acid Catalyzed [3 + 2]-Cycloaddition of Cyclic Enamides with in Situ Generated 2-Methide-2H-indoles: Enantioselective Synthesis of Indolo[1,2-a]indoles

(2016) Kalisankar Bera et al.   ORGANIC LETTERS

Formal Asymmetric Catalytic Thiolation with a Bifunctional Catalyst at a Water-Oil Interface: Synthesis of Benzyl Thiols

(2015) Wengang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalyzed Cycloadditions with Unactivated Alkenes by Exclusive Activation of the Electrophile

(2015) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generatedortho-Quinone Methides with 3-Methyl-2-Vinylindoles

(2015) Jia-Jia Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Organocatalytic Asymmetric Prins Cyclization

(2015) Gavin Chit Tsui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of dihydrocoumarin derivatives by chiral scandium(iii)-complex catalyzed inverse-electron-demand hetero-Diels–Alder reaction

(2015) Haipeng Hu et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

(2015) Anna Lee et al.   CHEMICAL COMMUNICATIONS

Chiral Brønsted acid-catalyzed Friedel–Crafts alkylation of electron-rich arenes with in situ-generated ortho-quinone methides: highly enantioselective synthesis of diarylindolylmethanes and triarylmethanes

(2015) Satyajit Saha et al.   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric Addition of Meldrum’s Acid, Malononitrile, and 1,3-Dicarbonyls toortho-Quinone Methides Generated In Situ Under Basic Conditions

(2015) Lorenzo Caruana et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Annulation of Donor–Acceptor Cyclopropanes with Dienes

(2015) Hao Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of Triarylmethanes by Rhodium-Catalyzed Enantioselective Arylation of Diarylmethylamines with Arylboroxines

(2015) Yinhua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Cycloaddition Reactions Catalyzed by BINOL-Derived Phosphoric Acids and N-Triflyl Phosphoramides: Recent Advances

(2015) Felix Held et al.   MOLECULES

The Emergence of Quinone Methides in Asymmetric Organocatalysis

(2015) Lorenzo Caruana et al.   MOLECULES

[4 + 3] Cycloadditions with Bromo-Substituted Morita–Baylis–Hillman Adducts of Isatins and N-(ortho-Chloromethyl)aryl Amides

(2015) Gu Zhan et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Nucleophilic Addition to o-Quinone Methides by Alcohols

(2015) Zengwei Lai et al.   ORGANIC LETTERS

Directing Group Assisted Nucleophilic Substitution of Propargylic Alcohols via o-Quinone Methide Intermediates: Brønsted Acid Catalyzed, Highly Enantio- and Diastereoselective Synthesis of 7-Alkynyl-12a-acetamido-Substituted Benzoxanthenes

(2015) Satyajit Saha et al.   ORGANIC LETTERS

Recent Advances in Chiral Phosphoric Acid Catalyzed Asymmetric Reactions for the Synthesis of Enantiopure Indole Derivatives

(2015) Hua Wu et al.   SYNTHESIS-STUTTGART

Recent Advances in Catalytic Asymmetric Reactions of o-Quinone Methides

(2015) Jianwei Sun et al.   SYNTHESIS-STUTTGART

The Domestication of ortho-Quinone Methides

(2014) Wen-Ju Bai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantio- and Diastereoselective Access to Distant Stereocenters Embedded within Tetrahydroxanthenes: Utilizingortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalysis

(2014) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Divergent Synthesis of Nitrogen Heterocycles by Rhodium(II)-Catalyzed Cycloadditions of 1-Sulfonyl 1,2,3-Triazoles with 1,3-Dienes

(2014) Hai Shang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Arylative Dearomatization of 2,3-Disubstituted Indoles Enabled by Tandem Reactions

(2014) Yu-Chen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Catalyzed, Conjugate Addition of β-Dicarbonyls to In Situ Generatedortho-Quinone Methides-Enantioselective Synthesis of 4-Aryl-4H-Chromenes

(2014) Osama El-Sepelgy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Formation of All-Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

(2014) Wanxiang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral phosphoramide-catalyzed enantioselective synthesis of 2,3′-diindolylarylmethanes from indol-2-yl carbinols and indoles

(2014) Shuai Qi et al.   CHEMICAL COMMUNICATIONS

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Brønsted Acid-Catalyzed, Highly Enantioselective Addition of Enamides to In Situ-Generatedortho-Quinone Methides: A Domino Approach to Complex Acetamidotetrahydroxanthenes

(2014) Satyajit Saha et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Synthesis of 1,1-Diarylethanes by Transfer Hydrogenation

(2014) Zhaobin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic functionalization of tertiary alcohols to fully substituted carbon centres

(2014) Long Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Et3N-Catalyzed Tandem Formal [4 + 3] Annulation/Decarboxylation/Isomerization of Methyl Coumalate with Imine Esters: Access to Functionalized Azepine Derivatives

(2014) Kang Liu et al.   ORGANIC LETTERS

ortho-Quinone methide (o-QM): a highly reactive, ephemeral and versatile intermediate in organic synthesis

(2014) Maya Shankar Singh et al.   RSC Advances

Alkylideneindoleninium Ions and Alkylideneindolenines: Key Intermediates for the Asymmetric Synthesis of 3-Indolyl Derivatives

(2014) Liang Wang et al.   Asian Journal of Organic Chemistry

N-Heterocyclic Carbene Catalyzed [4+3] Annulation of Enals ando-Quinone Methides: Highly Enantioselective Synthesis of Benzo-ε-Lactones

(2013) Hui Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Organocatalytic Construction of Hexahydropyrroloindole by Means of α-Alkylation of Aldehydes Leading to the Total Synthesis of (+)-Gliocladin C

(2013) Jin Song et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations

(2013) Javier Izquierdo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ortho-Quinone Methides in Natural Product Synthesis

(2012) Nicky J. Willis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Addition of Boronates to o-Quinone Methides Catalyzed by Chiral Biphenols

(2012) Yi Luan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Multistep One-Pot Synthesis of Enantioenriched Polysubstituted Cyclopenta[b]indoles

(2011) Biao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core-Structure-Oriented Asymmetric Organocatalytic Substitution of 3-Hydroxyoxindoles: Application in the Enantioselective Total Synthesis of (+)-Folicanthine

(2011) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

(4+3) Cycloaddition Reactions of Nitrogen-Stabilized Oxyallyl Cations

(2011) Andrew G. Lohse et al.   CHEMISTRY-A EUROPEAN JOURNAL

Applications ofortho-Quinone Methide Intermediates in Catalysis and Asymmetric Synthesis

(2011) Tejas P. Pathak et al.   JOURNAL OF ORGANIC CHEMISTRY

The (4+3)-cycloaddition reaction: heteroatom-substituted allylic cations as dienophiles

(2010) Michael Harmata   CHEMICAL COMMUNICATIONS

The (4+3)-cycloaddition reaction: simple allylic cations as dienophiles

(2010) Michael Harmata   CHEMICAL COMMUNICATIONS

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Organocatalytic Asymmetric Alkylation of Aldehydes by SN1-Type Reaction of Alcohols

(2009) Pier Giorgio Cozzi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Fluorene Derivatives by Chiral Phosphoric Acid Catalyzed Tandem Double Friedel-Crafts Reaction

(2009) Feng-Lai Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 3-substituted indoles via reactive alkylideneindolenine intermediates

(2009) Alessandro Palmieri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis

(2009) Qi-Xiang Guo et al.   ORGANIC LETTERS

AnN,N′-Dioxide/In(OTf)3 Catalyst for the Asymmetric Hetero-Diels–Alder Reaction Between Danishefsky's Dienes and Aldehydes: Application in the Total Synthesis of Triketide

(2008) Zhipeng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Asymmetric Cycloadditions ofo-Quinone Methides Employing Chiral Ammonium Fluoride Precatalysts

(2008) Ethan Alden-Danforth et al.   ORGANIC LETTERS