Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration

Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy

(2019) Lei Han et al.   ADVANCED MATERIALS

A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System

(2019) Di Wu et al.   ADVANCED MATERIALS

Severe Toxicity in Nonhuman Primates and Piglets Following High-Dose Intravenous Administration of an Adeno-Associated Virus Vector Expressing Human SMN

(2018) Christian Hinderer et al.   HUMAN GENE THERAPY

Dual-function injectable angiogenic biomaterial for the repair of brain tissue following stroke

(2018) Lina R. Nih et al.   NATURE MATERIALS

Nanocomposites Inhibit the Formation, Mitigate the Neurotoxicity, and Facilitate the Removal of β-Amyloid Aggregates in Alzheimer’s Disease Mice

(2018) Yu Zhao et al.   NANO LETTERS

Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo

(2018) Qi Liu et al.   Advanced Science

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

Evolution of blood-brain-barrier permeability after acute ischemic stroke

(2017) Zamir Merali et al.   PLoS One

Phosphorylcholine polymer nanocapsules prolong the circulation time and reduce the immunogenicity of therapeutic proteins

(2016) Sheng Liang et al.   Nano Research

AD-Peptide Ligand of Nicotine Acetylcholine Receptors for Brain-Targeted Drug Delivery

(2015) Xiaoli Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core

(2015) Andrew J. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

(2014) Wujin Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of Vascular Disruption and Blood–Spinal Cord Barrier Permeability following Traumatic Spinal Cord Injury

(2013) Sarah A. Figley et al.   JOURNAL OF NEUROTRAUMA

Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor

(2013) D. T. Wiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroblast survival depends on mature vascular network formation after mouse stroke: role of endothelial and smooth muscle progenitor cell co-administration

(2012) Lina R. Nih et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Nerve growth factor: from the early discoveries to the potential clinical use

(2012) Luigi Aloe et al.   Journal of Translational Medicine

Current advances in using neurotrophic factors to treat neurodegenerative disorders

(2012) April M Weissmiller et al.   Translational Neurodegeneration

Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery

(2011) Jianfeng Li et al.   ADVANCED MATERIALS

Protein Nanocapsule Weaved with Enzymatically Degradable Polymeric Network

(2009) Zhen Gu et al.   NANO LETTERS

A novel intracellular protein delivery platform based on single-protein nanocapsules

(2009) Ming Yan et al.   Nature Nanotechnology

Viral vectors for neurotrophic factor delivery: A gene therapy approach for neurodegenerative diseases of the CNS

(2009) Seung T. Lim et al.   PHARMACOLOGICAL RESEARCH

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Biomaterials for the central nervous system

(2008) Y. Zhong et al.   Journal of the Royal Society Interface

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY