Diet-induced metabolic changes of the human gut microbiome: importance of short-chain fatty acids, methylamines and indoles

The effects of probiotics and synbiotic supplementation on glucose and insulin metabolism in adults with prediabetes: a double-blind randomized clinical trial

(2018) Nazila Kassaian et al.   ACTA DIABETOLOGICA

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota

(2018) Lesley Hoyles et al.   Microbiome

Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential

(2018) Adam B. Roberts et al.   NATURE MEDICINE

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

(2017) Marc-Emmanuel Dumas et al.   Cell Reports

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro

(2016) Attilio Pingitore et al.   DIABETES OBESITY & METABOLISM

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Serotonin controlling feeding and satiety

(2015) Jörg-Peter Voigt et al.   BEHAVIOURAL BRAIN RESEARCH

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease

(2015) Lucile Garidou et al.   Cell Metabolism

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

(2015) Christopher S. Reigstad et al.   FASEB JOURNAL

Depressive symptoms, anxiety and well-being among metabolic health obese subtypes

(2015) Catherine M. Phillips et al.   PSYCHONEUROENDOCRINOLOGY

NMR Spectroscopy for Metabolomics and Metabolic Profiling

(2014) Cynthia K. Larive et al.   ANALYTICAL CHEMISTRY

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L -Carnitine to TMAO

(2014) Robert A. Koeth et al.   Cell Metabolism

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

(2014) A Psichas et al.   INTERNATIONAL JOURNAL OF OBESITY

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

(2014) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Colonic bacterial metabolites and human health

(2013) Wendy R Russell et al.   CURRENT OPINION IN MICROBIOLOGY

Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host

(2013) Vadivel Ganapathy et al.   CURRENT OPINION IN PHARMACOLOGY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Human intestinal microbiota composition is associated with local and systemic inflammation in obesity

(2013) Froukje J. Verdam et al.   Obesity

Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

(2012) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk

(2012) Elaine Holmes et al.   Cell Metabolism

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Propionate. Anti-obesity and satiety enhancing factor?

(2011) Tulika Arora et al.   APPETITE

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

LC-MS-based metabolomics

(2011) Bin Zhou et al.   Molecular BioSystems

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Overweight, Obesity, and Depression

(2010) Floriana S. Luppino et al.   ARCHIVES OF GENERAL PSYCHIATRY

G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer

(2010) Yong Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Short chain fatty acids exchange across the gut and liver in humans measured at surgery

(2009) Johanne G. Bloemen et al.   CLINICAL NUTRITION

Short chain fatty acids exchange: Is the cirrhotic, dysfunctional liver still able to clear them?

(2009) Johanne G. Bloemen et al.   CLINICAL NUTRITION

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological concentrations of short-chain fatty acids immediately suppress colonic epithelial permeability

(2008) Takuya Suzuki et al.   BRITISH JOURNAL OF NUTRITION