High-Throughput Fluorescence Polarization Assay to Identify Ligands Using Purified G Protein-Coupled Receptor

SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands

(2017) Sylwia Huber et al.   PLoS One

ZINC 15 – Ligand Discovery for Everyone

(2015) Teague Sterling et al.   Journal of Chemical Information and Modeling

Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies

(2014) Daniel J. Scott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Screening Technologies for Small Molecule Discovery: The State of the Art

(2014) William P. Janzen   CHEMISTRY & BIOLOGY

Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution inEscherichia coli

(2014) Pascal Egloff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of ML314, a Brain Penetrant Nonpeptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor

(2013) Satyamaheshwar Peddibhotla et al.   ACS Medicinal Chemistry Letters

Maximizing Detergent Stability and Functional Expression of a GPCR by Exhaustive Recombination and Evolution

(2012) Karola M. Schlinkmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Molecular Evolution of Detergent-Stable G Protein-Coupled Receptors Using Polymer Encapsulated Cells

(2012) Daniel J. Scott et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of neurotensin in physiologic and pathologic processes

(2011) W Conan Mustain et al.   Current Opinion in Endocrinology Diabetes and Obesity