Models of buffering of dosage imbalances in protein complexes

Lean forward: Genetic analysis of temperature-sensitive mutants unfolds the secrets of oligomeric protein complex assembly

(2014) Michael McMurray   BIOESSAYS

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast

(2014) Noah Dephoure et al.   eLife

Dominance and interloci interactions in transcriptional activation cascades: Models explaining compensatory mutations and inheritance patterns

(2013) Bruno Bost et al.   BIOESSAYS

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

Gene dosage effects: nonlinearities, genetic interactions, and dosage compensation

(2013) Reiner A. Veitia et al.   TRENDS IN GENETICS

Differential Translation Tunes Uneven Production of Operon-Encoded Proteins

(2013) Tessa E.F. Quax et al.   Cell Reports

Fractionation mutagenesis and similar consequences of mechanisms removing dispensable or less-expressed DNA in plants

(2012) Michael Freeling et al.   CURRENT OPINION IN PLANT BIOLOGY

Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

(2012) Silvia Stingele et al.   Molecular Systems Biology

Mutational Robustness of Gene Regulatory Networks

(2012) Aalt D. J. van Dijk et al.   PLoS One

Gene balance hypothesis: Connecting issues of dosage sensitivity across biological disciplines

(2012) J. A. Birchler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Evolutionary optimization of speed and accuracy of decoding on the ribosome

(2011) I. Wohlgemuth et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Identification of Aneuploidy-Tolerating Mutations

(2010) Eduardo M. Torres et al.   CELL

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

(2010) Norman Pavelka et al.   NATURE

Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

(2010) Tamar Geiger et al.   PLoS Genetics

Intrinsic Protein Disorder and Interaction Promiscuity Are Widely Associated with Dosage Sensitivity

(2009) Tanya Vavouri et al.   CELL

Disorder, Promiscuity, and Toxic Partnerships

(2009) Edward M. Marcotte et al.   CELL

Perturbation Waves in Proteins and Protein Networks: Applications of Percolation and Game Theories in Signaling and Drug Design

(2009) Miklos Antal et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

A generalized model of gene dosage and dominant negative effects in macromolecular complexes

(2009) Reiner A. Veitia   FASEB JOURNAL

Complex topology rather than complex membership is a determinant of protein dosage sensitivity

(2009) Richard Oberdorf et al.   Molecular Systems Biology

Cellular reactions to gene dosage imbalance: genomic, transcriptomic and proteomic effects

(2008) Reiner A. Veitia et al.   TRENDS IN GENETICS