Decoration of Anti-CD38 on Nanoparticles Carrying a STAT3 Inhibitor Can Improve the Therapeutic Efficacy Against Myeloma

Modulation of in vitro phagocytic uptake and immunogenicity potential of modified Herceptin ® -conjugated PLGA-PEG nanoparticles for drug delivery

(2018) Apurva Badkas et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Enhancing proteasome-inhibitory activity and specificity of bortezomib by CD38 targeted nanoparticles in multiple myeloma

(2018) Pilar de la Puente et al.   JOURNAL OF CONTROLLED RELEASE

In vivo evaluation of cetuximab-conjugated poly(γ-glutamic acid)-docetaxel nanomedicines in EGFR-overexpressing gastric cancer xenografts

(2017) Maya Sreeranganathan et al.   International Journal of Nanomedicine

Effective targeting of gemcitabine to pancreatic cancer through PEG-cored Flt-1 antibody-conjugated dendrimers

(2017) Kıvılcım Öztürk et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Targeting transferrin receptor delivery of temozolomide for a potential glioma stem cell-mediated therapy

(2017) Ting Sun et al.   Oncotarget

Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma

(2017) Amir H. Soleimani et al.   Drug Delivery and Translational Research

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

(2016) Yuko Nakamura et al.   BIOCONJUGATE CHEMISTRY

Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent

(2016) M. Xiang et al.   BLOOD

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling

(2016) Xing-Ding Zhang et al.   CANCER CELL

Potential crosstalk of the interleukin-6-heme oxygenase-1-dependent mechanism involved in resistance to lenalidomide in multiple myeloma cells

(2016) Weibing Wu et al.   FEBS Journal

Targeted Nanocurcumin Therapy Using Annexin A2 Antibody Improves Tumor Accumulation and Therapeutic Efficacy Against Highly Metastatic Breast Cancer

(2016) Anindita Mukerjee et al.   Journal of Biomedical Nanotechnology

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway

(2016) Zubin Zhang et al.   Oncotarget

Molecularly targeted gemcitabine-loaded nanoparticulate system towards the treatment of EGFR overexpressing lung cancer

(2015) Xian-Bao Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Trastuzumab guided nanotheranostics: A lipid based multifunctional nanoformulation for targeted drug delivery and imaging in breast cancer therapy

(2015) Priyambada Parhi et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Targeted antitumor efficacy and imaging via multifunctional nano-carrier conjugated with anti-HER2 trastuzumab

(2015) Won Il Choi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Phase I Study of OPB-31121, an Oral STAT3 Inhibitor, in Patients with Advanced Solid Tumors

(2015) Do-Youn Oh et al.   Cancer Research and Treatment

Curcumin-loaded PLGA Nanoparticles Conjugated with Anti-P-glycoprotein Antibody to Overcome Multidrug Resistance

(2015) Wanisa Punfa et al.   Asian Pacific Journal of Cancer Prevention

Multifunctional HER2-Antibody Conjugated Polymeric Nanocarrier-Based Drug Delivery System for Multi-Drug-Resistant Breast Cancer Therapy

(2014) Raju Vivek et al.   ACS Applied Materials & Interfaces

Anti-CD30 antibody conjugated liposomal doxorubicin with significantly improved therapeutic efficacy against anaplastic large cell lymphoma

(2013) Ommoleila Molavi et al.   BIOMATERIALS

A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

(2013) X. Zhang et al.   CANCER RESEARCH

Interleukin-6 and JAK2/STAT3 signaling mediate the reversion of dexamethasone resistance after dexamethasone withdrawal in 7TD1 multiple myeloma cells

(2013) Tuoen Liu et al.   LEUKEMIA RESEARCH

Antibody Conjugated PLGA Nanoparticles for Targeted Delivery of Paclitaxel Palmitate: Efficacy and Biofate in a Lung Cancer Mouse Model

(2013) Nour Karra et al.   Small

Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells

(2012) Wanisa Punfa et al.   ACTA PHARMACOLOGICA SINICA

Multimodality treatment of cancer with herceptin conjugated, thermomagnetic iron oxides and docetaxel loaded nanoparticles of biodegradable polymers

(2012) Yu Mi et al.   BIOMATERIALS

Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca2+ influx and induces streamers

(2011) Paul V. Beum et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

(2011) Li Lin et al.   INTERNATIONAL JOURNAL OF CANCER

Enhanced antiproliferative activity of Herceptin (HER2)-conjugated gemcitabine-loaded chitosan nanoparticle in pancreatic cancer therapy

(2011) Geetanjali Arya et al.   Nanomedicine-Nanotechnology Biology and Medicine

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

(2010) Xiaolei Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Multiple Myeloma and Other Hematological Tumors

(2010) M. de Weers et al.   JOURNAL OF IMMUNOLOGY

Antibody-Conjugated Nanoparticles for Biomedical Applications

(2009) Manuel Arruebo et al.   Journal of Nanomaterials

Polymeric micelles for the solubilization and delivery of STAT3 inhibitor cucurbitacins in solid tumors

(2007) Ommoleila Molavi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS