T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy

CD4+ T cell-mediated rejection of MHC class II-positive tumor cells is dependent on antigen secretion and indirect presentation on host APCs

(2018) Ole Audun Werner Haabeth et al.   CANCER RESEARCH

Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity

(2018) Marte Fauskanger et al.   Frontiers in Immunology

Tumor mutational burden is a determinant of immune-mediated survival in breast cancer

(2018) Alexandra Thomas et al.   OncoImmunology

Citrullination only infrequently impacts peptide binding to HLA class II MHC

(2017) John Sidney et al.   PLoS One

Autophagy, citrullination and cancer

(2016) Lindy G. Durrant et al.   Autophagy

The Prerequisites for Central Tolerance Induction against Citrullinated Proteins in the Mouse

(2016) Robby Engelmann et al.   PLoS One

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

(2016) Christina Gerstner et al.   Frontiers in Immunology

SCIB2, an antibody DNA vaccine encoding NY-ESO-1 epitopes, induces potent antitumor immunity which is further enhanced by checkpoint blockade

(2016) Wei Xue et al.   OncoImmunology

Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell-Mediated Antitumor Immunity

(2015) V. A. Brentville et al.   CANCER RESEARCH

Anti-citrullinated peptides as autoantigens in rheumatoid arthritis—relevance to treatment

(2014) Lazaros I. Sakkas et al.   AUTOIMMUNITY REVIEWS

Delineating the Role of the HLA-DR4 "Shared Epitope" in Susceptibility versus Resistance to Develop Arthritis

(2014) V. Taneja et al.   JOURNAL OF IMMUNOLOGY

Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen

(2014) Dres Damgaard et al.   ARTHRITIS RESEARCH & THERAPY

Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy

(2014) Eddie A. James et al.   Arthritis & Rheumatology

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

(2013) Stephen W. Scally et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Novel Variant Marking HLA-DP Expression Levels Predicts Recovery from Hepatitis B Virus Infection

(2012) R. Thomas et al.   JOURNAL OF VIROLOGY

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients

(2011) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

(2011) Jamie M. Ireland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Weak CD4+ T-cell responses to citrullinated vimentin in rheumatoid arthritis patients carrying HLA-DR9 alleles

(2011) Diego Catalán et al.   RHEUMATOLOGY INTERNATIONAL

HLA-DR1001 presents “altered-self” peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets

(2010) Eddie A. James et al.   ARTHRITIS AND RHEUMATISM

HLA-DP, HLA-DQ, and HLA-DR Have Different Requirements for Invariant Chain and HLA-DM

(2010) Marcel van Lith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Five HLA-DP Molecules Frequently Expressed in the Worldwide Human Population Share a Common HLA Supertypic Binding Specificity

(2010) John Sidney et al.   JOURNAL OF IMMUNOLOGY

Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis

(2009) Anouk L. Feitsma et al.   ARTHRITIS AND RHEUMATISM

Autophagy and Its Role in MHC-Mediated Antigen Presentation

(2009) V. L. Crotzer et al.   JOURNAL OF IMMUNOLOGY