Article
Genetics & Heredity
Lijun Shi, Yang Li, Qian Liu, Longchao Zhang, Ligang Wang, Xin Liu, Hongmei Gao, Xinhua Hou, Fuping Zhao, Hua Yan, Lixian Wang
Summary: This study focused on exploring sow lactation performance, estimating the heritability of litter weight gain (LWG) as an indicator for milk production ability, and identifying seven significant SNPs related to milk production in Yorkshire pigs. Further analysis revealed potential candidate genes involved in lactose metabolism, colostrum immunity, milk protein, and milk fat, providing valuable insights into improving milk production in pigs.
FRONTIERS IN GENETICS
(2021)
Article
Genetics & Heredity
Dev Paudel, Rocheteau Dareus, Julia Rosenwald, Maria Munoz-Amatriain, Esteban F. Rios
Summary: Cowpea, a major crop used for human consumption and livestock feed, has been studied for its genetic basis of flowering time through genome-wide association studies, revealing seven reliable SNP markers and candidate genes associated with flowering time, which could facilitate breeding efforts and knowledge transfer to other legume species.
FRONTIERS IN GENETICS
(2021)
Article
Genetics & Heredity
Hui Zhang, Zhanwei Zhuang, Ming Yang, Rongrong Ding, Jianping Quan, Shenping Zhou, Ting Gu, Zheng Xu, Enqin Zheng, Gengyuan Cai, Jie Yang, Zhenfang Wu
Summary: The study mapped genetic markers and genes associated with body conformation traits in DLY pigs through GWAS, identifying candidate genes related to body weight and conformation traits. Notably, the BMP2 gene was proposed as a strong candidate gene for body size due to its pleiotropic effects on various body traits. Pathway analysis indicated associations with cell growth regulation, cell population proliferation, and chondrocyte differentiation.
FRONTIERS IN GENETICS
(2021)
Article
Biochemistry & Molecular Biology
Seong-Hoon Kim, Rupesh Tayade, Byeong-Hee Kang, Bum-Soo Hahn, Bo-Keun Ha, Yoon-Ha Kim
Summary: This study conducted a genome-wide association study (GWAS) on 357 soybean landraces to analyze root traits. It identified 112 significant SNP loci and 55 putative candidate genes. These findings suggest that the combined approach of SNP array and GWAS can be used to understand the genetic basis of soybean root traits and improve soybean breeding.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Genetics & Heredity
V. G. Ishwarya Lakshmi, M. Sreedhar, V. JhansiLakshmi, C. Gireesh, Santosha Rathod, Rajaguru Bohar, Santosh Deshpande, R. Laavanya, K. N. S. Usha Kiranmayee, Sreedhar Siddi, S. Vanisri
Summary: This study identified marker-trait associations related to brown planthopper resistance in rice through SNP genotyping data and developed SNP markers for identifying resistant genotypes. The results showed that the Bph17 and Bph32 genes could be validated using gene specific SNPs and transferred to other rice varieties. This has important implications for breeding resistant rice varieties against the brown planthopper.
FRONTIERS IN GENETICS
(2022)
Article
Fisheries
Stavroula Oikonomou, Zoi Kazlari, Maria Papapetrou, Kantham Papanna, Leonidas Papaharisis, Tereza Manousaki, Dimitrios Loukovitis, Arkadios Dimitroglou, Lefteris Kottaras, Evgenia Gourzioti, Charalampos Pagonis, Andreas Kostandis, Costas S. Tsigenopoulos, Dimitiros Chatziplis
Summary: The study focuses on the genetic variation of resistance against parasitic diseases in European seabass, as well as its relationship with growth and weight. Moderate genomic heritability was found for growth at sea cage and weight at different growth stages. There was a moderate to low genomic correlation between parasites and growth. GWAS results identified two potential genomic regions associated with host resistance to Lernanthropus kroyeri, each explaining approximately 2% of the phenotypic variation.
AQUACULTURE REPORTS
(2022)
Article
Agriculture, Dairy & Animal Science
Masoud Alipanah, Zahra Roudbari, Mehdi Momen, Ali Esmailizadeh
Summary: This study aimed to assess the impact of non-additive effects on the estimation of genetic parameters for body weight traits in sheep. The results showed that non-additive genetic effects play an important role in controlling body weight variation at the age of 16-24 weeks in Scottish Blackface lambs. Therefore, joint modeling of additive and non-additive effects can lead to better estimation and prediction of genetic parameters.
ANIMAL BIOTECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Peng Su, Hui Wu, Yangming Huang, Xiaofang Lu, Jing Yin, Qingfeng Zhang, Xianyong Lan
Summary: Studying the characteristics of mammalian hoof colors is important for genetic improvements in animals. In this study, a specific single-nucleotide polymorphism (SNP) in the MITF gene was found to be significantly associated with hoof color in Australian White sheep. This research provides novel insights into hoof color genetics and offers molecular markers for selecting sheep with desired hoof color.
Article
Chemistry, Multidisciplinary
Mi-Yeon Cha, Ja-Eun Choi, Da-Som Lee, So-Ra Lee, Sang-In Lee, Jong-Ho Park, Jin-Hee Shin, In Soo Suh, Byung Ho Kim, Kyung-Won Hong
Summary: This study confirmed six genetic skin indexes and identified SNP loci associated with facial skin characteristics. Although some previously identified SNPs were not replicated, this study has the potential to contribute to future research on cosmetic-related genes.
APPLIED SCIENCES-BASEL
(2022)
Article
Biology
Yunfeng Zhao, Jin Gao, Xiugang Guo, Baofeng Su, Haijie Wang, Runqing Yang, Li Jiang
Summary: This study proposes an efficient gene-based GWAS method for studying economic traits in maize. By comparing different statistical methods, many candidate genes related to maize traits were identified, supporting the reliability of the method. These findings are significant for maize breeding.
Article
Plant Sciences
Rahele Panahabadi, Asadollah Ahmadikhah, Lauren S. McKee, Paer K. Ingvarsson, Naser Farrokhi
Summary: The genetic variability of MLG and starch contents in rice whole grains was analyzed, revealing a negative correlation between MLG content and grain starch content. A new genome-wide association study identified seven significant QTLs associated with MLG content and two QTLs associated with starch content. Novel genes related to MLG content included a hexose transporter and anthocyanidin 5,3-O-glucosyltransferase.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Genetics & Heredity
Zheng Chang Wu, Yifu Wang, Xiaoguo Huang, Shenglong Wu, Wenbin Bao
Summary: Improving the reproductive efficiency of sows is a major challenge in the swine industry. This study identified genetic markers associated with reproductive traits in Large White pigs and suggested the use of marker-assisted selection for genetic improvement.
Article
Agriculture, Dairy & Animal Science
Ismail Mohamed Abdalla, Jiang Hui, Mudasir Nazar, Abdelaziz Adam Idriss Arbab, Tianle Xu, Shaima Mohamed Nasr Abdu, Yongjiang Mao, Zhangping Yang, Xubin Lu
Summary: Body size is an important economic trait for dairy cows, and understanding the genetic basis of inter-individual variation in body size can accelerate genetic improvement programs. In this genome-wide association study on Chinese Holstein cattle, several genes and functional pathways related to body size traits were identified. These findings can contribute to breeding programs and genomic selection efforts.
Review
Immunology
Yueqi Qiu, Delong Feng, Wenjuan Jiang, Tingting Zhang, Qianjin Lu, Ming Zhao
Summary: Three-dimensional (3D) genomics investigates the relationship between gene regulatory function and the spatial structure of chromatin. It uses technologies like chromosome conformation capture (3C) to study chromatin folding and its impact on gene function. Integration of multi-omics data is crucial for a comprehensive analysis of the relationships between regulatory components and gene function. 3D genome folding plays a role in immune cell differentiation, activation, and dysfunction, and is involved in various diseases including autoimmune diseases.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Xubin Lu, Ismail Mohamed Abdalla, Mudasir Nazar, Yongliang Fan, Zhipeng Zhang, Xinyue Wu, Tianle Xu, Zhangping Yang
Summary: This study investigated the genetic parameters and genome-wide association of reproductive ability indicators in dairy cows, identifying several key candidate genes related to reproduction which could contribute to the improvement of production performance in dairy cows.