microRNA-34a (miRNA-34a) Mediated Down-Regulation of the Post-synaptic Cytoskeletal Element SHANK3 in Sporadic Alzheimer's Disease (AD)

Dysbiosis of microbiome and probiotic treatment in a genetic model of autism spectrum disorders

(2018) Laure Tabouy et al.   BRAIN BEHAVIOR AND IMMUNITY

Up-regulated Pro-inflammatory MicroRNAs (miRNAs) in Alzheimer’s disease (AD) and Age-Related Macular Degeneration (AMD)

(2018) Aileen I. Pogue et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

SHANK3 variant as a cause of nonsyndromal autism in an 11-year-old boy and a review of published literature

(2018) Farah Kanani et al.   CLINICAL DYSMORPHOLOGY

Synapse-to-nucleus communication: from developmental disorders to Alzheimer's disease

(2018) Elena Marcello et al.   CURRENT OPINION IN NEUROBIOLOGY

Molecular biomarkers of Alzheimer's disease: progress and prospects

(2018) Tammaryn Lashley et al.   Disease Models & Mechanisms

The miRNome of bipolar disorder

(2018) Gabriel R. Fries et al.   JOURNAL OF AFFECTIVE DISORDERS

MicroRNAs as predictive biomarkers for myocardial injury in aged mice following myocardial infarction

(2018) Natia Qipshidze Kelm et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Microglia-Mediated Synapse Loss in Alzheimer's Disease

(2018) Lawrence Rajendran et al.   JOURNAL OF NEUROSCIENCE

Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function

(2018) Haitham Amal et al.   MOLECULAR PSYCHIATRY

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

miR-34a directly targets tRNAiMetprecursors and affects cellular proliferation, cell cycle, and apoptosis

(2018) Bo Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer’s disease model

(2018) Dong Hyun Kim et al.   Scientific Reports

Microbiome-Mediated Upregulation of MicroRNA-146a in Sporadic Alzheimer’s Disease

(2018) Yuhai Zhao et al.   Frontiers in Neurology

RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer’s Associated Cognitive Deficits

(2018) Dongdong Zhao et al.   BIOLOGICAL PSYCHIATRY

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

MicroRNA-34a targets regulator of calcineurin 1 to modulate endothelial inflammation after fetal cardiac bypass in goat placenta

(2017) Hai-Yun Yuan et al.   PLACENTA

Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations

(2017) Yeunkum Lee et al.   Frontiers in Molecular Neuroscience

Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder

(2017) Dominik Reim et al.   Frontiers in Molecular Neuroscience

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders

(2017) Peter N. Alexandrov et al.   Frontiers in Neurology

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

(2016) Surjyadipta Bhattacharjee et al.   PLoS One

Analysis of RNA from Alzheimer’s Disease Post-mortem Brain Tissues

(2015) Christian Clement et al.   MOLECULAR NEUROBIOLOGY

Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

(2015) Su-Yeon Choi et al.   Molecular Brain

A framework to understand the variations of PSD-95 expression in brain aging and in Alzheimer's disease

(2014) Armand Savioz et al.   AGEING RESEARCH REVIEWS

Synaptic proteins and receptors defects in autism spectrum disorders

(2014) Jianling Chen et al.   Frontiers in Cellular Neuroscience

Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice

(2014) Xiaoming Wang et al.   Molecular Autism

The emerging role ofSHANKgenes in neuropsychiatric disorders

(2013) Audrey Guilmatre et al.   Developmental Neurobiology

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders

(2013) Li Zhu et al.   HUMAN MOLECULAR GENETICS

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

New roles for “old” microRNAs in nervous system function and disease

(2013) Marion Hartl et al.   Frontiers in Molecular Neuroscience

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

Progressive accumulation of amyloid-β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins

(2010) Emiley Pham et al.   FEBS Journal

miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation

(2009) Xiaoying Wang et al.   BRAIN RESEARCH BULLETIN

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH