CD4+CD25highCD127low/-FoxP3+ Regulatory T-Cell Population in Acute Leukemias: A Review of the Literature

BCR-ABL1 -like acute lymphoblastic leukaemia: From bench to bedside

(2017) Judith M. Boer et al.   EUROPEAN JOURNAL OF CANCER

Frequency of regulatory T cells determines the outcome of the T-cell-engaging antibody blinatumomab in patients with B-precursor ALL

(2017) J Duell et al.   LEUKEMIA

Novel agents for the treatment of childhood leukemia: an update

(2017) Ertugrul Eryılmaz et al.   OncoTargets and Therapy

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

(2017) T Terwilliger et al.   Blood Cancer Journal

New Therapeutic Strategies in Acute Lymphocytic Leukemia

(2017) Louise M. Man et al.   Current Hematologic Malignancy Reports

Safety and efficacy of intrathecal rituximab in children with B cell lymphoid CD20+ malignancies: An international retrospective study

(2016) Francesco Ceppi et al.   AMERICAN JOURNAL OF HEMATOLOGY

Reduced frequency of circulating CD4+CD25brightCD127lowFOXP3+ regulatory T cells in primary myelofibrosis

(2016) M. Massa et al.   BLOOD

Natural killer cell (NK) subsets and NK-like T-cell populations in acute myeloid leukemias and myelodysplastic syndromes

(2016) N. Aggarwal et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Increased regulatory T cells in acute lymphoblastic leukaemia patients

(2016) Siti-Zuleha Idris et al.   Hematology

Regulatory T Cells and Cancer: A Two-Sided Story

(2016) Kepeng Wang et al.   IMMUNOLOGICAL INVESTIGATIONS

Ontogeny of Tumor-associated CD4+CD25+Foxp3+ T-regulatory Cells

(2016) Qingsheng Li et al.   IMMUNOLOGICAL INVESTIGATIONS

Roles of regulatory T cells in cancer immunity

(2016) Yoshiko Takeuchi et al.   INTERNATIONAL IMMUNOLOGY

Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia

(2016) Arend von Stackelberg et al.   JOURNAL OF CLINICAL ONCOLOGY

Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes

(2016) Natalia Marek-Trzonkowska et al.   Journal of Translational Medicine

New monoclonal antibodies for the treatment of acute lymphoblastic leukemia

(2016) Nosha Farhadfar et al.   LEUKEMIA RESEARCH

Regulatory T Cells: Differentiation and Function

(2016) G. Plitas et al.   Cancer Immunology Research

Manipulation of regulatory T cells and antigen-specific cytotoxic T lymphocyte-based tumour immunotherapy

(2015) Shirin Karimi et al.   IMMUNOLOGY

Re-induction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL): Phase II results from Children's Oncology Group (COG) study ADVL04P2

(2015) Elizabeth A. Raetz et al.   PEDIATRIC BLOOD & CANCER

Hurdles in therapy with regulatory T cells

(2015) Piotr Trzonkowski et al.   Science Translational Medicine

Rituximab with chemotherapy in children and adolescents with central nervous system and/or bone marrow-positive Burkitt lymphoma/leukaemia: a Children's Oncology Group Report

(2014) Stanton Goldman et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab

(2014) P. Schlegel et al.   HAEMATOLOGICA

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

(2014) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

Does the Immune System Naturally Protect Against Cancer?

(2014) Alexandre Corthay   Frontiers in Immunology

Antibody Therapy for Pediatric Leukemia

(2014) Aditi Vedi et al.   Frontiers in Oncology

High Proportions of CD4+ T Cells among Residual Bone Marrow T Cells in Childhood Acute Lymphoblastic Leukemia Are Associated with Favorable Early Responses

(2013) Imke Lustfeld et al.   ACTA HAEMATOLOGICA

Critical stoichiometric ratio of CD4+ CD25+ FoxP3+regulatory T cells and CD4+ CD25−responder T cells influence immunosuppression in patients with B-cell acute lymphoblastic leukaemia

(2013) Kaushik Bhattacharya et al.   IMMUNOLOGY

Influence of pharmacological immunomodulatory agents on CD4+CD25highFoxP3+ T regulatory cells in humans

(2013) Xiao-Jun Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Clinical significance of Treg cell frequency in acute myeloid leukemia

(2013) Wenjuan Yang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

A shorter time to the first treatment may be predicted by the absolute number of regulatory T-cells in patients with Rai stage 0 chronic lymphocytic leukemia

(2012) Giovanni D'Arena et al.   AMERICAN JOURNAL OF HEMATOLOGY

How I treat relapsed childhood acute lymphoblastic leukemia

(2012) F. Locatelli et al.   BLOOD

Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL

(2012) M. S. Topp et al.   BLOOD

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

(2012) C.-H. Pui et al.   BLOOD

Induced and natural regulatory T cells in human cancer

(2012) Theresa L. Whiteside et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

What are regulatory T cells (Treg) regulating in cancer and why?

(2012) Theresa L. Whiteside   SEMINARS IN CANCER BIOLOGY

Human FoxP3+ regulatory T cells in systemic autoimmune diseases

(2011) Makoto Miyara et al.   AUTOIMMUNITY REVIEWS

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study

(2011) M. Schrappe et al.   BLOOD

Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?

(2011) C. Ustun et al.   BLOOD

Nature and nurture in Foxp3+ regulatory T cell development, stability, and function

(2011) Terrence L. Geiger et al.   HUMAN IMMUNOLOGY

Human FoxP3+ CD4+ regulatory T cells: their knowns and unknowns

(2011) Makoto Miyara et al.   IMMUNOLOGY AND CELL BIOLOGY

CD4+CD25highFoxP3+Regulatory T-cells in Hematologic Diseases

(2011) Hee-Won Moon et al.   Korean Journal of Laboratory Medicine

CREBBP mutations in relapsed acute lymphoblastic leukaemia

(2011) Charles G. Mullighan et al.   NATURE

Immunophenotype and increased presence of CD4+CD25+ regulatory T cells in patients with acute lymphoblastic leukemia

(2011) CUI-PING WU et al.   Oncology Letters

T regulatory cells in cancer: recent advances and therapeutic potential

(2010) Eyad Elkord et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Regulatory T cells in tumor immunity

(2010) Hiroyoshi Nishikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Elevated frequencies of CD4+CD25+CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia

(2010) Zhang Shenghui et al.   INTERNATIONAL JOURNAL OF CANCER

Clinical Outcome of Children With Newly Diagnosed Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia Treated Between 1995 and 2005

(2010) Maurizio Aricò et al.   JOURNAL OF CLINICAL ONCOLOGY

Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease

(2010) Giovanni D’Arena et al.   LEUKEMIA RESEARCH

Increased Frequency and Suppression by Regulatory T Cells in Patients with Acute Myelogenous Leukemia

(2009) M. J. Szczepanski et al.   CLINICAL CANCER RESEARCH

Dynamics of peripheral tolerance and immune regulation mediated by Treg

(2009) Shimon Sakaguchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

(2009) Kirk R. Schultz et al.   JOURNAL OF CLINICAL ONCOLOGY

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

(2009) Stephen Malin et al.   NATURE IMMUNOLOGY

Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia

(2009) Charles G. Mullighan et al.   NEW ENGLAND JOURNAL OF MEDICINE

How do Regulatory T Cells Work?

(2009) A. Corthay   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma

(2008) S. Mittal et al.   BLOOD

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Regulatory T cells and treatment of cancer

(2008) Tyler J Curiel   CURRENT OPINION IN IMMUNOLOGY

Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma

(2008) A. Tzankov et al.   HAEMATOLOGICA

Tumor-specific regulatory T cells in cancer patients

(2008) Sytse J. Piersma et al.   HUMAN IMMUNOLOGY

CD8+ regulatory T cells, their suppressive mechanisms, and regulation in cancer

(2008) Rong-Fu Wang   HUMAN IMMUNOLOGY

Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody

(2008) R. Bargou et al.   SCIENCE

Immunoregulatory T cells: Role and potential as a target in malignancy

(2008) Marc Beyer et al.   Current Oncology Reports

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology