Article
Cardiac & Cardiovascular Systems
E. A. Polyakova, M. I. Zaraiskii, E. N. Mikhaylov, E. I. Baranova, M. M. Galagudza, E. V. Shlyakhto
Summary: The study demonstrated that the expressions of myocardial and serum miRNA-27a, miRNA-133a, and miRNA-203 were significantly higher in CAD patients compared to non-CAD subjects. The serum expression level of miRNA-203 correlated strongly with myocardial expression and was associated with the extent of coronary atherosclerosis.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
David Duncker, Martin Svetlosak, Federico Guerra, Klaudia Vivien Nagy, Philippe Vanduynhoven, Evgeny N. Mikhaylov, Jedrzej Kosiuk
Summary: Data on reprocessing of electrophysiology (EP) materials are limited. A survey conducted among European electrophysiologists shows that the use of reprocessed EP materials is generally considered safe and cost-effective, with concerns mainly focusing on quality, contamination, and precision loss.
Article
Respiratory System
Natalia S. Goncharova, Heber Ivan Condori Leandro, Aleksandr D. Vakhrushev, Elena G. Koshevaya, Yury A. Skorik, Lubov B. Mitrofanova, Lada A. Murashova, Lev E. Korobchenko, Elizaveta M. Andreeva, Dmitry S. Lebedev, Olga M. Moiseeva, Evgeny N. Mikhaylov
Summary: Pulmonary artery denervation (PADN) did not affect pulmonary hypertension induced by thromboxane A2. However, significant adventitia damage in the pulmonary artery was associated with accelerated heart rate after PADN. Further research is needed to explore the potential delayed effects of PADN on perivascular nerves and pulmonary hemodynamics in chronic experiments.
BMC PULMONARY MEDICINE
(2021)
Article
Biotechnology & Applied Microbiology
Aleksandr D. Vakhrushev, Heber Ivan Condori Leonardo, Natalia S. Goncharova, Lev E. Korobchenko, Lubov B. Mitrofanova, Elizaveta M. Andreeva, Elena G. Koshevaya, Dmitry S. Lebedev, Evgeny N. Mikhaylov
Summary: The study on the effects of renal denervation (RDN) on thromboxane A2- (TXA2-) induced pulmonary arterial hypertension (PAH) in a swine model did not show significant acute changes in pulmonary or systemic hemodynamics. However, further research is needed to assess the potential chronic effects of RDN on PAH.
BIOMED RESEARCH INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Ekaterina A. Polyakova, Evgeny N. Mikhaylov, Michael M. Galagudza, Evgeny Shlyakhto
Summary: The study demonstrated that long-term hyperleptinemia in rats can negatively impact cardiac structure and function, leading to issues such as myocardial hypertrophy and myocardial infarction. Blocking the JAK/STAT signaling pathway effectively reverses these negative effects of leptin.
Editorial Material
Cardiac & Cardiovascular Systems
Nicholay Teodorovich, Evgeny N. Mikhaylov, Lubov B. Mitrofanova, Moshe Swissa
Article
Cardiac & Cardiovascular Systems
Nigar Z. Gasimova, Anatoly A. Nechepurenko, Evgeny B. Kropotkin, Eduard A. Ivanitsky, Grigorii Kolunin, Dmitry A. Shavshin, Bor Antolic, Elena A. Artyukhina, Ayan S. Abdrakhmanov, Konstantin S. Korolev, Dmitry S. Lebedev, Evgeny N. Mikhaylov
Summary: The study aimed to assess the achievement of target AI values and their impact on FPI, as well as identify predictors of FPI in AF ablation procedures. The study found that a significant proportion of patients did not achieve FPI and target AI values. Higher actual and target AI values were associated with FPI, but only carina ablation was an independent predictor of FPI.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2022)
Article
Medicine, General & Internal
Ekaterina B. Luneva, Anastasia A. Vasileva, Elena Karelkina, Maria A. Boyarinova, Evgeny N. Mikhaylov, Anton Ryzhkov, Alina Y. Babenko, Alexandra O. Konradi, Olga M. Moiseeva
Summary: This study aimed to identify simple predictors of cardiac fibrosis in patients with diabetes mellitus. The study found that an increased serum galectin-3 level was associated with left ventricular concentric hypertrophy in patients with type 2 diabetes. Additionally, the study explored the relationship between fibrosis biomarkers and arterial stiffness with cardiac fibrosis.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Anatomy & Morphology
Aleksandr D. Vakhrushev, Heber Ivan Condori Leandro, Natalia S. Goncharova, Lev E. Korobchenko, Lubov B. Mitrofanova, Igor A. Makarov, Elizaveta M. Andreeva, Dmitry S. Lebedev, Evgeny N. Mikhaylov
Summary: This study evaluated the effects of laser ablation compared to radiofrequency ablation on renal artery and perivascular nerve injury. The results showed that laser ablation was noninferior to radiofrequency ablation in terms of perivascular nerve injury and was associated with less damage to the intimal layer.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2022)
Article
Biology
Natalia N. N. Beliaeva, Tatiana R. R. Moshonkina, Oleg V. V. Mamontov, Elena N. N. Zharova, Heber Ivan Condori Leandro, Nigar Z. Z. Gasimova, Evgeny N. N. Mikhaylov
Summary: Orthostatic hypotension is a complex medical problem, and transcutaneous spinal cord stimulation (t-SCS) may be a potential treatment option. A feasibility study involving three patients with orthostatic hypotension showed that t-SCS led to elevated blood pressure in a supine position. Further investigation on a larger patient population is needed to validate these results.
Article
Medicine, General & Internal
Martina Nesti, Fabiana Luca, David Duncker, Francesco De Sensi, Katarzyna Malaczynska-Rajpold, Jonathan M. Behar, Victor Waldmann, Ahmed Ammar, Gianluca Mirizzi, Rodrigue Garcia, Ahran Arnold, Evgeny N. Mikhaylov, Jedrzej Kosiuk, Luigi Sciarra
Summary: Our survey indicates that the management of anti-thrombotic therapy surrounding left-sided endocardial ablation of patients without other indications for anti-thrombotic therapy is highly variable. Further studies are necessary to evaluate the safest approach to these procedures.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Ekaterina A. Polyakova, Evgeny N. Mikhaylov, Sarkis M. Minasian, Mikhail M. Galagudza, Evgeny V. Shlyakhto
Summary: This study investigated the concentration-dependent effects of leptin on myocardial ischemia-reperfusion injury (IRI) and analyzed the expression of miRNAs in the myocardium. The results showed that the addition of 1.0 nM leptin can reduce infarct size, protect cardiac function, and prevent reperfusion arrhythmia. Furthermore, the expression of miRNA-208a in the myocardium was altered.
Meeting Abstract
Peripheral Vascular Disease
Mikhail Ionov, Igor Emelyanov, Aleksander Vakhrushev, Asiyat Alieva, Natalia Avdonina, Yulia Yudina, Dmitry Lebedev, Evgeny Mikhaylov, Aleksandra Konradi
JOURNAL OF HYPERTENSION
(2022)
Meeting Abstract
Peripheral Vascular Disease
Mikhail Ionov, Igor Emelyanov, Aleksander Vakhrushev, Asiyat Alieva, Natalia Avdonina, Yulia Yudina, Dmitry Lebedev, Evgeny Mikhaylov, Aleksandra Konradi
JOURNAL OF HYPERTENSION
(2022)
Review
Cardiac & Cardiovascular Systems
Evgeny N. Mikhaylov, Nigar Z. Gasimova, Natalia N. Belyaeva, Heber Ivan Condori Leandro, Aleksandr D. Vakhrushev, Evgeny Shlyakhto
Summary: The autonomic nervous system plays a crucial role in the development of cardiovascular diseases. Aging leads to changes in autonomic activity, affecting physiological responses to internal and external signals. This article discusses the impact of device-based neuromodulation on various cardiovascular diseases, considering the age of the patients. The results of clinical studies on neuromodulation interventions have been inconclusive, suggesting that age may contribute to a poorer response.
JOURNAL OF GERIATRIC CARDIOLOGY
(2022)