Conditional Silencing by CRISPRi Reveals the Role of DNA Gyrase in Formation of Drug-Tolerant Persister Population in Mycobacterium tuberculosis

Interdependence of bacterial cell division and genome segregation and its potential in drug development

(2018) Hari S. Misra et al.   MICROBIOLOGICAL RESEARCH

Timing of DNA damage responses impacts persistence to fluoroquinolones

(2018) Wendy W. K. Mok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary Mechanisms Shaping the Maintenance of Antibiotic Resistance

(2018) Paulo Durão et al.   TRENDS IN MICROBIOLOGY

ATP-Dependent Persister Formation in Escherichia coli

(2017) Yue Shan et al.   mBio

Generation of Persister Cells of Pseudomonas aeruginosa and Staphylococcus aureus by Chemical Treatment and Evaluation of Their Susceptibility to Membrane-Targeting Agents

(2017) Lucia Grassi et al.   Frontiers in Microbiology

Repurposing and Revival of the Drugs: A New Approach to Combat the Drug Resistant Tuberculosis

(2017) Divakar Sharma et al.   Frontiers in Microbiology

Delamanid and Bedaquiline Resistance inMycobacterium tuberculosisAncestral Beijing Genotype Causing Extensively Drug-Resistant Tuberculosis in a Tibetan Refugee

(2016) Harald Hoffmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The preprotein translocase YidC controls respiratory metabolism in Mycobacterium tuberculosis

(2016) Preeti Thakur et al.   Scientific Reports

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

(2015) Derek J. Sloan et al.   CLINICAL INFECTIOUS DISEASES

Phenotypic resistance in mycobacteria: is it because I am old or fat that I resist you?

(2015) Robert J. H. Hammond et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antibiotic efficacy is linked to bacterial cellular respiration

(2015) Michael A. Lobritz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in Mycobacterium tuberculosis

(2015) Yu-Min Chuang et al.   mBio

Gene silencing by CRISPR interference in mycobacteria

(2015) Eira Choudhary et al.   Nature Communications

Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery

(2014) Astha Nautiyal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors

(2014) Tuhin Bhowmick et al.   Nature Communications

Evaluation of DNA Primase DnaG as a Potential Target for Antibiotics

(2013) Aneta Kuron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Establishment of a Method To Rapidly Assay Bacterial Persister Metabolism

(2013) Mehmet A. Orman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microbial Persistence and the Road to Drug Resistance

(2013) Nadia R. Cohen et al.   Cell Host & Microbe

Role of Oxidative Stress in Persister Tolerance

(2012) Yanxia Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Metabolite-enabled eradication of bacterial persisters by aminoglycosides

(2011) Kyle R. Allison et al.   NATURE

Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling

(2011) Christopher A Sellick et al.   Nature Protocols

Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli

(2011) S. Gon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization and Transcriptome Analysis of Mycobacterium tuberculosis Persisters

(2011) I. Keren et al.   mBio

Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format

(2011) Leslie Hall et al.   Jove-Journal of Visualized Experiments

Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice

(2010) N. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

(2009) Chirajyoti Deb et al.   PLoS One

SOS Response Induces Persistence to Fluoroquinolones in Escherichia coli

(2009) Tobias Dörr et al.   PLoS Genetics

Role of Global Regulators and Nucleotide Metabolism in Antibiotic Tolerance in Escherichia coli

(2008) S. Hansen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacterial DNA topology and infectious disease

(2008) C. J. Dorman et al.   NUCLEIC ACIDS RESEARCH

Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum

(2008) Natalie J Garton et al.   PLOS MEDICINE