Function and Role of ATP-Binding Cassette Transporters as Receptors for 3D-Cry Toxins

Cell lines as models for the study of Cry toxins from Bacillus thuringiensis

(2018) Mario Soberón et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The intracellular region of silkworm cadherin-like protein is not necessary to mediate the toxicity of Bacillus thuringiensis Cry1Aa and Cry1Ab toxins

(2018) Haruka Endo et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A single amino acid polymorphism in ABCC2 loop 1 is responsible for differential toxicity of Bacillus thuringiensis Cry1Ac toxin in different Spodoptera (Noctuidae) species

(2018) Leilei Liu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Extracellular loop structures in silkworm ABCC transporters determine their specificities forBacillus thuringiensisCry toxins

(2018) Haruka Endo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacillus thuringiensis Cry1A toxins exert toxicity by multiple pathways in insects

(2018) Shaohua Wang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The C-terminal protoxin region of Bacillus thuringiensis Cry1Ab toxin has a functional role in binding to GPI-anchored receptors in the insect midgut

(2018) Arlen Peña-Cardeña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRISPR/Cas9 mediated genome editing of Helicoverpa armigera with mutations of an ABC transporter gene HaABCA2 confers resistance to Bacillus thuringiensis Cry2A toxins

(2017) Jing Wang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bombyx mori ABC transporter C2 structures responsible for the receptor function of Bacillus thuringiensis Cry1Aa toxin

(2017) Shiho Tanaka et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor

(2017) Tristan Stevens et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Proteomic analysis of Cry1Ac and Cry2Aa binding proteins in brush border membrane vesicles of the Chilo suppressalis midgut

(2017) Lin Qiu et al.   JOURNAL OF ASIA-PACIFIC ENTOMOLOGY

Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters

(2017) Haruka Endo et al.   PEPTIDES

Proteomic analysis of Cry1Ac and Cry2Aa binding proteins in brush border membrane vesicles of the Chilo suppressalis midgut

(2017) Lin Qiu et al.   JOURNAL OF ASIA-PACIFIC ENTOMOLOGY

Cry1Ac and Vip3Aa proteins fromBacillus thuringiensistargeting Cry toxin resistance inDiatraea flavipennellaandElasmopalpus lignosellusfrom sugarcane

(2017) Ana Rita Nunes Lemes et al.   PeerJ

ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth

(2017) Josue Ocelotl et al.   Scientific Reports

Functional characterization ofBacillus thuringiensisCry toxin receptors explains resistance in insects

(2016) Shiho Tanaka et al.   FEBS Journal

Water influx via aquaporin directly determines necrotic cell death induced by the Bacillus thuringiensis Cry toxin

(2016) Haruka Endo et al.   FEBS LETTERS

Know your ABCs: Characterization and gene expression dynamics of ABC transporters in the polyphagous herbivore Helicoverpa armigera

(2016) Anne Bretschneider et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Single amino acid insertions in extracellular loop 2 of Bombyx mori ABCC2 disrupt its receptor function for Bacillus thuringiensis Cry1Ab and Cry1Ac but not Cry1Aa toxins

(2016) Shiho Tanaka et al.   PEPTIDES

A P-Glycoprotein Is Linked to Resistance to the Bacillus thuringiensis Cry3Aa Toxin in a Leaf Beetle

(2016) Yannick Pauchet et al.   Toxins

Induction of rapid and selective cell necrosis in Drosophila using Bacillus thuringiensis Cry toxin and its silkworm receptor

(2015) Fumiaki Obata et al.   BMC BIOLOGY

Endogenous expression of a Bt toxin receptor in the Cry1Ac-susceptible insect cell line and its synergistic effect with cadherin on cytotoxicity of activated Cry1Ac

(2015) Zuwen Chen et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The novel ABC transporter ABCH1 is a potential target for RNAi-based insect pest control and resistance management

(2015) Zhaojiang Guo et al.   Scientific Reports

Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transporter Subfamily A Protein

(2015) Wee Tek Tay et al.   PLoS Genetics

ABCC transporters mediate insect resistance to multiple Bt toxins revealed by bulk segregant analysis

(2014) Youngjin Park et al.   BMC BIOLOGY

RNA interference-mediated knockdown of three putative aminopeptidases N affects susceptibility of Spodoptera exigua larvae to Bacillus thuringiensis Cry1Ca

(2014) Xiang-Liang Ren et al.   JOURNAL OF INSECT PHYSIOLOGY

Evaluation of the synergistic activities of Bacillus thuringiensis Cry proteins against Helicoverpa armigera (Lepidoptera: Noctuidae)

(2014) Hua Li et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Mis-splicing of the ABCC2 gene linked with Bt toxin resistance in Helicoverpa armigera

(2014) Yutao Xiao et al.   Scientific Reports

Oligomerization is a key step in Cyt1Aa membrane insertion and toxicity but not necessary to synergize Cry11Aa toxicity in Aedes aegypti larvae.

(2013) Jazmin A. López-Diaz et al.   ENVIRONMENTAL MICROBIOLOGY

The ATP-binding cassette transporter subfamily C member 2 inBombyx morilarvae is a functional receptor for Cry toxins fromBacillus thuringiensis

(2013) Shiho Tanaka et al.   FEBS Journal

Midgut aminopeptidase N isoforms from Ostrinia nubilalis: Activity characterization and differential binding to Cry1Ab and Cry1Fa proteins from Bacillus thuringiensis

(2013) Cristina M. Crava et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cadherin AdCad1 in Alphitobius diaperinus larvae is a receptor of Cry3Bb toxin from Bacillus thuringiensis

(2013) Gang Hua et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The ABC gene family in arthropods: Comparative genomics and role in insecticide transport and resistance

(2013) Wannes Dermauw et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Response of midgut epithelial cells to Cry1Aa is toxin-dependent and depends on the interplay between toxic action and the host apoptotic response

(2012) Shiho Tanaka et al.   FEBS Journal

Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in the silkworm, Bombyx mori

(2012) Xiaodong Xie et al.   MOLECULAR BIOLOGY REPORTS

Learning the ABCs of Bt: ABC transporters and insect resistance to Bacillus thuringiensis provide clues to a crucial step in toxin mode of action

(2012) David G. Heckel   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori

(2012) S. Atsumi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacillus thuringiensisCry Toxins Bound Specifically to Various ProteinsviaDomain III, Which Had a Galactose-Binding Domain-Like Fold

(2011) Madoka KITAMI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Parallel Evolution ofBacillus thuringiensisToxin Resistance in Lepidoptera

(2011) Simon W. Baxter et al.   GENETICS

Optimized Purification of a Heterodimeric ABC Transporter in a Highly Stable Form Amenable to 2-D Crystallization

(2011) Carmen Galián et al.   PLoS One

Formation of Macromolecule Complex with Bacillus thuringiensis Cry1A Toxins and Chlorophyllide Binding 252-kDa Lipocalin-Like Protein Locating on Bombyx mori Midgut Membrane

(2010) Ganesh N. Pandian et al.   JOURNAL OF MEMBRANE BIOLOGY

Persistence of Bacillus thuringiensis israelensis (Bti) in the environment induces resistance to multiple Bti toxins in mosquitoes

(2010) Margot Paris et al.   PEST MANAGEMENT SCIENCE

An ABC Transporter Mutation Is Correlated with Insect Resistance to Bacillus thuringiensis Cry1Ac Toxin

(2010) Linda J. Gahan et al.   PLoS Genetics

Cadherin Fragments from Anopheles gambiae Synergize Bacillus thuringiensis Cry4Ba's Toxicity against Aedes aegypti Larvae

(2009) Y. Park et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Identification and characterization of Aedes aegypti aminopeptidase N as a putative receptor of Bacillus thuringiensis Cry11A toxin

(2009) Jianwu Chen et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE