High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2

Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification

(2018) Kavi Mehta et al.   mBio

High-Risk Alphapapillomavirus Oncogenes Impair the Homologous Recombination Pathway

(2017) Nicholas A. Wallace et al.   JOURNAL OF VIROLOGY

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

(2017) Sylvie van Twest et al.   MOLECULAR CELL

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response

(2017) Elizabeth L. Thompson et al.   NUCLEIC ACIDS RESEARCH

Why Human Papillomaviruses Activate the DNA Damage Response (DDR) and How Cellular and Viral Replication Persists in the Presence of DDR Signaling

(2017) Molly Bristol et al.   Viruses-Basel

FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication

(2017) Chelsey C. Spriggs et al.   mBio

Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex

(2017) Ronald S. Cheung et al.   Cell Reports

Coordination of the recruitment of the FANCD2 and PALB2 Fanconi anemia proteins by an ubiquitin signaling network

(2016) Gregory Bick et al.   CHROMOSOMA

The Fanconi anaemia pathway: new players and new functions

(2016) Raphael Ceccaldi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

(2016) Koichi Sato et al.   NUCLEIC ACIDS RESEARCH

p53 downregulates the Fanconi anaemia DNA repair pathway

(2016) Sara Jaber et al.   Nature Communications

Artificial Recruitment of UAF1-USP Complexes by a PHLPP1-E1 Chimeric Helicase Enhances Human Papillomavirus DNA Replication

(2015) David Gagnon et al.   JOURNAL OF VIROLOGY

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers

(2015) Yihang Shen et al.   Oncotarget

UHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway

(2015) Chih-Chao Liang et al.   Cell Reports

UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold

(2015) Yanyan Tian et al.   Cell Reports

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

(2014) Qin Liang et al.   Nature Chemical Biology

OpenComet: An automated tool for comet assay image analysis

(2014) Benjamin M. Gyori et al.   Redox Biology

Squamous cell carcinomas in patients with Fanconi anemia and dyskeratosis congenita: A search for human papillomavirus

(2013) Blanche P. Alter et al.   INTERNATIONAL JOURNAL OF CANCER

Inactivation ofUaf1Causes Defective Homologous Recombination and Early Embryonic Lethality in Mice

(2013) Eunmi Park et al.   MOLECULAR AND CELLULAR BIOLOGY

High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7’s induction of DNA damage response, an activity mediated by E7’s inactivation of pocket proteins

(2013) J W Park et al.   ONCOGENE

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

The Fanconi Anemia Pathway Limits Human Papillomavirus Replication

(2012) E. E. Hoskins et al.   JOURNAL OF VIROLOGY

Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial Amplification

(2012) T. Reinson et al.   JOURNAL OF VIROLOGY

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers

(2012) K. A. Gillespie et al.   JOURNAL OF VIROLOGY

HPV 5 and 8 E6 Abrogate ATR Activity Resulting in Increased Persistence of UVB Induced DNA Damage

(2012) Nicholas A. Wallace et al.   PLoS Pathogens

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

(2011) S. A. Williams et al.   BLOOD

MicroRNA-138 Modulates DNA Damage Response by Repressing Histone H2AX Expression

(2011) Y. Wang et al.   MOLECULAR CANCER RESEARCH

Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor

(2011) M A Rego et al.   ONCOGENE

High prevalence of oral human papillomavirus infection in Fanconi’s anemia patients

(2011) MR de Araujo et al.   ORAL DISEASES

Deficiencies in the Fanconi Anemia DNA Damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer

(2010) J. W. Park et al.   CANCER RESEARCH

RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network

(2010) Liyi Geng et al.   JOURNAL OF CELL BIOLOGY

Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes

(2010) Muy-Teck Teh et al.   Molecular Cancer

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

Functional Interaction between the Fanconi Anemia D2 Protein and Proliferating Cell Nuclear Antigen (PCNA) via a Conserved Putative PCNA Interaction Motif

(2009) Niall G. Howlett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PALB2 Regulates Recombinational Repair through Chromatin Association and Oligomerization

(2009) Shirley M.-H. Sy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2

(2009) F. Zhang et al.   MOLECULAR CANCER RESEARCH

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

HPV-16 E7 Reveals a Link between DNA Replication Stress, Fanconi Anemia D2 Protein, and Alternative Lengthening of Telomere-Associated Promyelocytic Leukemia Bodies

(2008) N. Spardy et al.   CANCER RESEARCH

Kinetics of H2AX phosphorylation after exposure to cisplatin

(2008) Peggy L. Olive et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Clinical and Molecular Characteristics of Squamous Cell Carcinomas From Fanconi Anemia Patients

(2008) Hester J. T. van Zeeburg et al.   JNCI-Journal of the National Cancer Institute

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

(2008) Masamichi Ishiai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway

(2008) E E Hoskins et al.   ONCOGENE

Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture

(2008) E E Hoskins et al.   ONCOGENE