Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches

In-host microevolution of Aspergillus fumigatus : A phenotypic and genotypic analysis

(2018) Eloise Ballard et al.   FUNGAL GENETICS AND BIOLOGY

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

(2018) Matthew C. Fisher et al.   SCIENCE

Gene flow contributes to diversification of the major fungal pathogen Candida albicans

(2018) Jeanne Ropars et al.   Nature Communications

Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris

(2018) Johanna Rhodes et al.   Emerging Microbes & Infections

Nature's genetic screens: using genome-wide association studies for effector discovery

(2017) Andrea Sánchez-Vallet et al.   MOLECULAR PLANT PATHOLOGY

Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

(2017) R Blake Billmyre et al.   eLife

Simultaneous Emergence of Multidrug-ResistantCandida aurison 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

(2016) Shawn R. Lockhart et al.   CLINICAL INFECTIOUS DISEASES

CRISPR-Cas9, the new kid on the block of fungal molecular biology

(2016) Sven Krappmann   MEDICAL MYCOLOGY

Multilocus resistance evolution to azole fungicides in fungal plant pathogen populations

(2016) Norfarhan Mohd-Assaad et al.   MOLECULAR ECOLOGY

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging

(2016) Bernd Timmermann et al.   Aging-US

Next-generation sequencing offers new insights into the resistance ofCandidaspp. to echinocandins and azoles

(2015) Cécile Garnaud et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans

(2015) Kwang-Woo Jung et al.   Nature Communications

Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Mismatch Repair Mutants

(2015) Irene Ojini et al.   G3-Genes Genomes Genetics

Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus’s Role in Virulence

(2015) Liliana Losada et al.   PLoS Pathogens

Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

(2014) A. Y. Lee et al.   SCIENCE

Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes

(2014) Tobias Schwarzmüller et al.   PLoS Pathogens

Analysis of a fungus-specific transcription factor family, theCandida albicanszinc cluster proteins, by artificial activation

(2013) Rebecca Schillig et al.   MOLECULAR MICROBIOLOGY

Expression quantitative trait loci: present and future

(2013) A. C. Nica et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mutation Rates, Spectra, and Genome-Wide Distribution of Spontaneous Mutations in Mismatch Repair Deficient Yeast

(2013) Gregory I. Lang et al.   G3-Genes Genomes Genetics

Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

(2013) Benjamin Matteson Vincent et al.   PLOS BIOLOGY

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing

(2012) Simone M. T. Camps et al.   PLoS One

Global Analysis of the Evolution and Mechanism of Echinocandin Resistance in Candida glabrata

(2012) Sheena D. Singh-Babak et al.   PLoS Pathogens

Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes

(2010) Edward Sionov et al.   PLoS Pathogens

A genome-wide view of the spectrum of spontaneous mutations in yeast

(2008) M. Lynch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA