Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

2018 Alzheimer's disease facts and figures

(2018)   Alzheimers & Dementia

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

Polygenic score prediction captures nearly all common genetic risk for Alzheimer's disease

(2017) Valentina Escott-Price et al.   NEUROBIOLOGY OF AGING

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

(2017) Rahul S. Desikan et al.   PLOS MEDICINE

Use of Genetic Variation as Biomarkers for Mild Cognitive Impairment and Progression of Mild Cognitive Impairment to Dementia

(2017) Christiane Reitz et al.   JOURNAL OF ALZHEIMERS DISEASE

Genomic variants, genes, and pathways of Alzheimer's disease: An overview

(2016) Adam C. Naj et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging

(2016) Lorraine Hamelin et al.   BRAIN

Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment

(2016) A Lacour et al.   MOLECULAR PSYCHIATRY

Polygenic risk of Alzheimer disease is associated with early- and late-life processes

(2016) Elizabeth C. Mormino et al.   NEUROLOGY

Predicting Progression from Mild Cognitive Impairment to Alzheimer's Dementia Using Clinical, MRI, and Plasma Biomarkers via Probabilistic Pattern Classification

(2016) Igor O. Korolev et al.   PLoS One

Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014

(2015) Michael W. Weiner et al.   Alzheimers & Dementia

Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis

(2015) Celeste M. Karch et al.   BIOLOGICAL PSYCHIATRY

GWAS of longitudinal amyloid accumulation on18F-florbetapir PET in Alzheimer’s disease implicates microglial activation geneIL1RAP

(2015) Vijay K Ramanan et al.   BRAIN

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Measurement of Longitudinal  -Amyloid Change with 18F-Florbetapir PET and Standardized Uptake Value Ratios

(2015) S. M. Landau et al.   JOURNAL OF NUCLEAR MEDICINE

Progression of mild cognitive impairment to dementia due to AD in clinical settings

(2015) Karim Tifratene et al.   NEUROLOGY

Hierarchical feature representation and multimodal fusion with deep learning for AD/MCI diagnosis

(2014) Heung-Il Suk et al.   NEUROIMAGE

Association of Lifetime Intellectual Enrichment With Cognitive Decline in the Older Population

(2014) Prashanthi Vemuri et al.   JAMA Neurology

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders

(2013) Eider M. Arenaza-Urquijo et al.   NEUROIMAGE

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

(2013) R. O. Roberts et al.   NEUROLOGY

Effect of Complement CR1 on Brain Amyloid Burden During Aging and Its Modification by APOE Genotype

(2012) Madhav Thambisetty et al.   BIOLOGICAL PSYCHIATRY

A coding variant in CR1 interacts with APOE-ɛ4 to influence cognitive decline

(2012) Brendan T. Keenan et al.   HUMAN MOLECULAR GENETICS

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults

(2012) Y. Y. Lim et al.   NEUROLOGY

Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

(2012) S. Barral et al.   NEUROLOGY

Predicting Future Clinical Changes of MCI Patients Using Longitudinal and Multimodal Biomarkers

(2012) Daoqiang Zhang et al.   PLoS One

Pathway analysis of genomic data: concepts, methods, and prospects for future development

(2012) Vijay K. Ramanan et al.   TRENDS IN GENETICS

Predictive value of APOE- 4 allele for progression from MCI to AD-type dementia: a meta-analysis

(2011) L. S. Elias-Sonnenschein et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core

(2010) William J. Jagust et al.   Alzheimers & Dementia

CR1is associated with amyloid plaque burden and age-related cognitive decline

(2010) Lori B. Chibnik et al.   ANNALS OF NEUROLOGY

Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes

(2010) Gyungah Jun   ARCHIVES OF NEUROLOGY

Comparing predictors of conversion and decline in mild cognitive impairment

(2010) S. M. Landau et al.   NEUROLOGY

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

(2010) Lesley Jones et al.   PLoS One

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Progression of Mild Cognitive Impairment to Dementia in Clinic- vs Community-Based Cohorts

(2009) Sarah Tomaszewski Farias et al.   ARCHIVES OF NEUROLOGY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods

(2008) Clifford R. Jack et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING